Cost minimization for bag-of-tasks workflows in a federation of clouds

We address the problem of resource allocation for bag-of-tasks (BoT) workflows in a federation of clouds and formulate it as an integer linear programming problem. The proposed model minimizes financial cost including fees for running VMs and fees for data transfer, and fulfills deadline and resource constraints in the clouds. We also formulate the problem of BoT scheduling in the hybrid clouds, and compare the financial cost in the federation of clouds with that in the hybrid clouds. Moreover, this paper discusses sensitivity analysis to investigate stability in the related allocation problem. Numerical results show that the resource allocation in the federation is considerably preferred to that in the hybrid clouds in terms of stability and cost-saving. In this paper, we also propose an approach named GRASP-FC for obtaining an approximate optimal solution of BoT scheduling in the federation. GRASP-FC is an extension of greedy randomized adaptive search procedure (GRASP), and it can be of great interest from the computational points of view.

     

Stress-Aware Periodic Test of Interconnects

Journal of Electronic Testing - Safety-critical systems have to follow extremely high dependability requirements as specified in the standards for automotive, air, and space applications. The...     

Optimal Newton–Secant like methods without memory for solving nonlinear equations with its dynamics

We construct two optimal Newton–Secant like iterative methods for solving nonlinear equations. The proposed classes have convergence order four and eight and cost only three and four function evaluations per iteration, respectively. These methods support the Kung and Traub conjecture and possess a high computational efficiency. The new methods are illustrated by numerical experiments and a comparison with some existing optimal methods. We conclude with an investigation of the basins of attraction of the solutions in the complex plane.     

Embedded of Nanogel into Multi-responsive Hydrogel Nanocomposite for Anticancer Drug Delivery

Hydrogels, nanogels, and nanocomposites show increasing potential for application in drug delivery systems due to their good chemical and physical properties. Therefore, we were encouraged to combine them to produce a new compound with unique properties for drug release systems. To this aim, we first prepared poly [(N-isopropylacrylamide)-co-(2-dimethylamino ethyl methacrylate) nanogel by copolymerization processes and then added it into the solution of poly (2-dimethylamino ethyl methacrylate)] grafted onto salep. Through dropwise addition of mixed aqueous solution of iron salts into the prepared polymeric solution, a novel hydrogel nanocomposite with excellent pH, thermo, and magnetic responsive was fabricated. The obtained hydrogel nanocomposite were characterized by Fourier transform infrared spectroscopy, thermo gravimetric analysis, X-ray diffraction, scanning electron microscopy, vibrating sample magnetometer, and atomic force micrographs. The dependence of swelling properties of hydrogel nanocomposite on the temperature, pH, and magnetic field were investigated. The release behavior of doxorubicin hydrochloride (DOX) drug from DOX loaded into synthesized hydrogel nanocomposite was investigated at different pHs, temperatures, and magnetic field. In addition, the drug release behavior from obtained hydrogel nanocomposite was monitored via different kinetic models. Lastly, the toxicity of the DOX and DOX-loaded hydrogel nanocomposite were studied on MCF-7 cells at different times. These results suggested that the obtained hydrogel nanocomposite might have high potential applications in drug delivery systems.     

A New Method Modifying Single Miller Feedforward Frequency Compensation to Drive Large Capacitive Loads: Putting an Attenuator in the Path

A new method to compensate three-stage amplifier to drive large capacitive loads is proposed in this paper. Gain Bandwidth Product is increased due to use an attenuator in the path of miller compensation capacitor. Analysis demonstrates that the gain bandwidth product will be improved significantly without using large compensation capacitor. Using a feedforward path is deployed to control a left half plane zero which is able to cancel out first non-dominant pole. A three stage amplifier is simulated in a 0.18 μm CMOS technology. The purpose of the design is to compensate three-stage amplifier loading 1000 pF capacitive load. The simulated amplifier with a 1000 pF capacitive load is performed in 3.3 MHz gain bandwidth product, and phase margin of 50. The compensation capacitor is reduced extremely compared to conventional nested miller compensation methods. Since transconductance of each stage is not distinct, and it is close to one another; as a result, this method is suitable low power design methodology.     

Enhancing robustness and perturbation tolerance of cognitive radio engines with metacognition

A cognitive radio engine (CE) is an intelligent agent which observes the radio environment and chooses the best communication settings that best meet the application’s goal. In this process, providing reliable performance is one of the major tasks in designing CEs for wireless communication systems. The main purpose of this work is providing predictable performance and controlling the cost of intelligent algorithms based on the CE’s experience and complexity analysis respectively. In this work, we extend our meta-CE design to control the cost of computations and provide more reliable performance for providing the minimum requirement of the radio applications in different scenarios. To achieve this, we use robust training algorithm (RoTA) in two different levels alongside of the individual CE algorithms. The RoTA, enables radio to guarantee some minimum output performance based on the learning stages. RoTA uses confidence interval approximation for standard normal distribution to calculate the lower and upper bounds of CE’s expected performance to analyze the reliability of decisions. Moreover, in the case of non-stationary environments, RoTA is facilitated by forgetfulness factor to provide minimum performance guarantees. The second level of RoTA operates in meta-level to control the amount of computation complexity of intelligent algorithms in all levels with respect to the obtained performance and complexity analysis.     

A routing algorithm for reducing optical loss in photonic Networks-on-Chip

Driven by increase in automation, smart homes play an important role in today’s human life. This paper presents a new model for smart home technologies based on multi-device bidirectional visible light communication (VLC). For multiple devices and users, orthogonal code-based wavelength division (color beams) full-duplexed bidirectional VLC link is proposed. The color beams from RGB LEDs are utilized to transmit data and synchronize multi-device transmission. To enhance the performance of the proposed model, receiver diversity is also employed. Performance evaluation reveals that the proposed VLC-based model for smart homes is efficient with superior BER performance in a typical smart home environment except for the far corners. The maximum achievable data rate for each user up to four users is found to be 24 Mbps at both uplink and downlink transmissions.     

Proposal for optical fiber designs with ultrahigh effective area and small bending loss applicable to long haul communications

A proposal for the multiclad MII optical fiber structure with ultralarge effective area and small bending loss is presented. For the proposed structure small dispersion and dispersion slope are obtained thanks to what we believe to be a novel design method. The suggested design method is based on a weighted fitness function, which is applied to the genetic algorithm optimization technique. In the meantime, the foregoing structure introduces a special fiber whose mode field diameter is small and approximately insensitive to the variation of the effective area. Compared to the work reported previously, our method can precisely set the zero dispersion wavelength. The designed dispersion-shifted single-mode fibers have effective area, mode field diameter, and quality factor respectively within [150-194.79] microm(2), [6.82-7.95] microm, and [3.04-3.85] at lambda(0)=1.55 microm. An analytical method is used for the calculation of the dispersion and its slope. These calculations give dispersion and dispersion slope of [(-2.57 x 10(-4))-(-0.085)] ps/km/nm and approximately 0.064 ps/km x nm(2), respectively.     

Quality preservation of minimally processed pomegranate cv. Jahrom arils based on chitosan and organic acid edible coatings

The effects of chitosan (CTS), ascorbic acid (AsA), and citric acid (CtA) on quality preservation of (Punica granatum cv. “Jahrom”) processed arils were investigated. The arils were immersed in aqueous solutions including water (control), CTS (0.5 and 1%), AsA (1 and 2%), and CtA (1 and 2%) and stored at 5–7°C for 15 days. Results showed that AsA maintained water loss; inhibited color change, phenolic, and anthocyanin degradation; increased vitamin C; and decreased total soluble solids and titratable acidity as compared to control. The efficiency was better for AsA than CtA and thus the effect of CTS on quality safety except to protect water loss was approximately ineffective. AsA also exhibited a significantly lower decay percentage, probably due to the suppressing peroxidase and polyphenol oxidase followed by improving antioxidant power and maintaining catalase activity, which displayed that AsA exerts an antibrowning effect. Moreover, the positive effects of AsA result in getting a higher score in sensory quality at the end storage.     

Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia

Environmentally-mediated drug resistance in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) significantly contributes to relapse. Stromal cells in the bone marrow environment protect leukemia cells by secretion of chemokines as cues for BCP-ALL migration towards, and adhesion to, stroma. Stromal cells and BCP-ALL cells communicate through stromal galectin-3. Here, we investigated the significance of stromal galectin-3 to BCP-ALL cells. We used CRISPR/Cas9 genome editing to ablate galectin-3 in stromal cells and found that galectin-3 is dispensable for steady-state BCP-ALL proliferation and viability. However, efficient leukemia migration and adhesion to stromal cells are significantly dependent on stromal galectin-3. Importantly, the loss of stromal galectin-3 production sensitized BCP-ALL cells to conventional chemotherapy. We therefore tested novel carbohydrate-based small molecule compounds (Cpd14 and Cpd17) with high specificity for galectin-3. Consistent with results obtained using galectin-3-knockout stromal cells, treatment of stromal-BCP-ALL co-cultures inhibited BCP-ALL migration and adhesion. Moreover, these compounds induced anti-leukemic responses in BCP-ALL cells, including a dose-dependent reduction of viability and proliferation, the induction of apoptosis and, importantly, the inhibition of drug resistance. Collectively, these findings indicate galectin-3 regulates BCP-ALL cell responses to chemotherapy through the interactions between leukemia cells and the stroma, and show that a combination of galectin-3 inhibition with conventional drugs can sensitize the leukemia cells to chemotherapy.