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31.
明眸晧齿,笑容爽朗,脸部轮廓分明。看到袁泉,马上会有清冽甘甜的感觉,一如她的名字,仿佛夏日里活力天然的一泓清泉。从《春天的狂想》到娃哈哈广告中的美丽少女,袁泉给人的印象一直是青春、健康而甜美的,举手投足,一颦一笑,洋溢着独有的耀眼活力。不久前,这位活力闰女更是担任了“中国女性健康白皮书系列活动”的形象大使。作为宣传女性健康的代言人,袁泉呼吁,要让更多的女性认识到:健康的身体才是美丽人生的根基。[编者按] 相似文献
32.
Wu Li Yann-Hang Lee Wei-Tek Tsai Jingjing Xu Young-Sung Son Jun-Hee Park Kyung-Duk Moon 《Service Oriented Computing and Applications》2012,6(1):65-79
A smart home usually has a variety of devices or home appliance, instead of designing software for a specific home, this paper
proposes a service-oriented framework with a set of ontology systems to support service and device publishing, discovery of
devices and their services, composition of control software using existing control services that wrap devices, deployment,
and execution of the composed service in an computing environment, monitoring the execution, and recovery from device failure.
The ontology systems specify semantic information about devices, services, and workflows used in various smart home, and users
can compose and recompose services for their specific needs. New devices, workflows, and services can be added into ontology.
Most of the steps in this process can be automated including code generation. For example, service composition will be carried
out in three steps: abstract workflow design, function construction, and device discovery, and different codes can be generated
for different computing platforms such as Java and Open Services Gateway initiative environments. In this way, a variety of
smart home can be constructed rapidly using the framework by discovery and composition using existing services and workflows.
This paper illustrates this framework using a media control example to illustrate the ontology, discovery, composition, deployment,
execution, monitoring, and recovery. 相似文献
33.
Yeonsil Moon Changmok Lim Yeahoon Kim Won-Jin Moon 《International journal of molecular sciences》2021,22(6)
The role of the blood–brain barrier (BBB) breakdown has been recognized as being important in Alzheimer’s disease pathogenesis. We aimed to evaluate whether regional BBB integrity differed according to sex and whether differences in BBB integrity changed as a consequence of aging or cognitive decline, using dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI). In total, 75 participants with normal cognition (NC) or mild cognitive impairment (MCI) underwent cognitive assessments and MRI examination including DCE-MRI. Regional Ktrans was calculated in cortical regions and the Patlak permeability model was used to calculate BBB permeability (Ktrans, min−1). Females had a lower median Ktrans in the cingulate and occipital cortices. In the “older old” group, sex differences in Ktrans were only observed in the occipital cortex. In the MCI group, sex differences in Ktrans were only observed in the occipital cortex. Age was the only predictor of cognitive assessment scores in the male MCI group; however, educational years and Ktrans in the occipital cortex could predict cognitive scores in the female MCI group. Our study revealed that females may have better BBB integrity in cingulate and occipital cortices. We also found that sex-related differences in BBB integrity are attenuated with aging or cognitive decline. 相似文献
34.
Jay Ronel V. Conejos Jalil Ghassemi Nejad Jung-Eun Kim Jun-Ok Moon Jae-Sung Lee Hong-Gu Lee 《International journal of molecular sciences》2021,22(5)
The objective of this study was to investigate the effects of supplementing with L-tryptophan (L-Trp) on milk protein synthesis using an immortalized bovine mammary epithelial (MAC-T) cell line. Cells were treated with 0, 0.3, 0.6, 0.9, 1.2, and 1.5 mM of supplemental L-Trp, and the most efficient time for protein synthesis was determined by measuring cell, medium, and total protein at 0, 24, 48, 72, and 96 h. Time and dose tests showed that the 48 h incubation time and a 0.9 mM dose of L-Trp were the optimal values. The mechanism of milk protein synthesis was elucidated through proteomic analysis to identify the metabolic pathway involved. When L-Trp was supplemented, extracellular protein (medium protein) reached its peak at 48 h, whereas intracellular cell protein reached its peak at 96 h with all L-Trp doses. β-casein mRNA gene expression and genes related to milk protein synthesis, such as mammalian target of rapamycin (mTOR) and ribosomal protein 6 (RPS6) genes, were also stimulated (p < 0.05). Overall, there were 51 upregulated and 59 downregulated proteins, many of which are involved in protein synthesis. The results of protein pathway analysis showed that L-Trp stimulated glycolysis, the pentose phosphate pathway, and ATP synthesis, which are pathways involved in energy metabolism. Together, these results demonstrate that L-Trp supplementation, particularly at 0.9 mM, is an effective stimulus in β-casein synthesis by stimulating genes, proteins, and pathways related to protein and energy metabolism. 相似文献
35.
Woohyeon Shin Jun Seop Kim Heesung Kim Hui Ju Choi Hee Jung Lee Moon Kwang Um Moon Kee Choi Kyeongwoon Chung 《大分子材料与工程》2021,306(5):2100007
Hydrogels are recognized as one of the most promising materials for e-skin devices because of their unique applicable functionalities such as flexibility, stretchability, biocompatibility, and conductivity. Beyond the excellent sensing functionalities, the e-skin devices further need to secure a target-oriented 3D structure to be applied onto various body parts having complex 3D shapes. However, most e-skin devices are still fabricated in simple 2D film-type devices, and it is an intriguing issue to fabricate complex 3D e-skin devices resembling target body parts via 3D printing. Here, a material design guideline is provided to prepare multifunctional hydrogels and their target-oriented 3D structures based on extrusion-based 3D printing. The material design parameters to realize target-oriented 3D structures via 3D printing are systematically derived from the correlation between material design of hydrogels and their gelation characteristics, rheological properties, and 3D printing processability for extrusion-based 3D printing. Based on the suggested material design window, ion conductive self-healable hydrogels are designed and successfully applied to extrusion-based 3D printing to realize various 3D shapes. 相似文献
36.
Measurements of non-methane hydrocarbons (NMHC) were performed at the entrance and exit of the Sangdo tunnel to estimate emission
factors (EF) of NMHC from vehicles in May 2000. About 50 species were analyzed by a combined GC/FID and GC/MS system. Ethylene
was the most abundant compound, followed by n-butane and acetylene, respectively. Based on the measurement data, the real
world vehicular EF in Seoul was estimated. The highest EF value was 89.8 mg (veh-mile)-1 for n-butane, followed by ethylene and toluene. 相似文献
37.
Well-defined Ln2Sn2O7 powders (Ln = La, Sm and Gd) with a phase-pure pyrochlore structure were synthesized by hydrothermal reaction. The catalytic activities of Ln2Sn2O7 powders for methane combustion were measured. Methane oxidation started at 500 °C and increased with oxidation temperature. Catalytic methane combustion is strongly influenced by the presence of oxygen vacancies that form by breaking Sn–O lattice bonds as the temperature increases. Addition of manganese to the rare earth pyrochlores improved methane oxidation activity. Manganese-doped samarium stannate pyrochlore (Sm2Sn1.8Mn0.2O7) shows highest the catalytic activity. Light-off and complete oxidation temperatures were measured at about 400 and 650 °C, respectively. 相似文献
38.
Optimization of reduction potential for electroseparation was studied for the recovery of gold, copper, and lead from acidic
solution. A linear sweep voltammetric method enabled us to determine characteristic reduction potentials for each metal and
the kinetics of the metal deposition indicated by current-voltage curves. In order to precipitate the metal species sequentially,
reduction potentials were examined for the individual and mixed solutions of Au(III), Cu(II), and Pb(II). The three metals
were reasonably well isolated from the mixed solutions such as Cu(II)/ Pb(II) and Au(III)/Cu(II)/Pb(II) in the order of the
corresponding reduction potentials, in particular, the mass transfer controlled reduction potentials, obtained from linear
sweep voltammetry (LSV) measurement. 相似文献
39.
Jung Joon Lee Heeyeon Kim Jae Hyun Koh Ara Jo Sang Heup Moon 《Applied catalysis. B, Environmental》2005,61(3-4):274-280
The performance of a new type of CoMoS/Al2O3 catalyst, with added fluorine and prepared by sonochemical and chemical vapor deposition (CVD) methods, was investigated in the hydrodesulfurization (HDS) of dibenzothiophene (DBT) and 4,6-dimethyldibenzothiophene (4,6-DMDBT). The catalyst, which was designed to contain optimum amounts of fluorine and cobalt, exhibited a higher activity, ca. 4.6 times higher activity particularly in the HDS of 4,6-DMDBT, than a fluorine-free catalyst prepared by a conventional impregnation method. The enhanced activity of the new catalyst can be attributed to the cumulative effects of individual factors involved in the catalyst preparation. That is, the use of a sonochemical synthesis led to a high dispersion of small MoS2 crystallites on the alumina, and the addition of the Co species to the catalyst by CVD caused a close interaction between the Co species and the MoS2 crystallites to produce numerous CoMoS species, which are the catalytically active species for HDS. The addition of fluorine increased the amounts of acidic sites in the catalyst, which promoted hydrogenation (HYD) route to a greater extent than the direct desulfurization (DDS) route in DBT HDS and both HYD and DDS routes to similar extents in the case of 4,6-DMDBT HDS. Accordingly, the addition of fluorine led to a greater increase in catalytic activity for 4,6-DMDBT HDS than for DBT HDS. 相似文献
40.
Neung‐Ju Lee Ja‐Chul Koo Sung‐Suk Ju Seong‐Bae Moon Won‐Jei Cho In‐Cheol Jeong Song‐Jae Lee Moo‐Youn Cho Emmanuel A Theodorakis 《Polymer International》2002,51(7):569-576
The attachment of anticancer agents to polymers is a promising approach towards reducing the toxic side‐effects and retaining the potent antitumour activity of these agents. A new tetrahydrophthalimido monomer containing 5‐fluorouracil (ETPFU) and its homopolymer and copolymers with acrylic acid (AA) and with vinyl acetate (VAc) have been synthesized and spectroscopically characterized. The ETPFU contents in poly(ETPFU‐co‐AA) and poly(ETPFU‐co‐VAc) obtained by elemental analysis were 21 mol% and 20 mol%, respectively. The average molecular weights of the polymers determined by gel permeation chromatography were as follows: Mn = 8900 g mol?1, Mw = 13 300 g mol?1, Mw/Mn = 1.5 for poly(ETPFU); Mn = 13 500 g mol?1, Mw = 16 600 g mol?1, Mw/Mn = 1.2 for poly(ETPFU‐co‐AA); Mn = 8300 g mol?1, Mw = 11 600 g mol?1, Mw/Mn = 1.4 poly(ETPFU‐co‐VAc). The in vitro cytotoxicity of the compounds against FM3A and U937 cancer cell lines increased in the following order: ETPFU > 5‐FU > poly(ETPFU) > poly(ETPFU‐co‐AA) > poly(ETPFU‐co‐VAc). The in vivo antitumour activities of all the polymers in Balb/C mice bearing the sarcoma 180 tumour cell line were greater than those of 5‐FU and monomer at the highest dose (800 mg kg?1). © 2002 Society of Chemical Industry 相似文献