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21.
Valasa  Sresta  Tayal  Shubham  Thoutam  Laxman Raju 《SILICON》2022,14(16):10347-10356
Silicon - This paper investigates the various device dimensions such as gate length (Lg), nanosheet thickness (TNS), and nanosheet width to optimize the design space for vertically stacked...  相似文献   
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BACKGROUND: The increase in drug‐resistant bacteria and the ban on antibiotic growth promoters worldwide make the search for novel means of preventing bacterial infection and promoting growth performance imperative. In this sense, antimicrobial peptides are thought to be ideal candidates owing to their antimicrobial properties, broad spectrum of activity and low propensity for development of bacterial resistance. The aim of the present study was to investigate the effect of dietary supplementation with antimicrobial peptide‐P5 (AMP‐P5) on weanling pig nutrition. RESULTS: A total of 240 weanling pigs were allotted to four treatments on the basis of initial body weight. There were four replicates in each treatment, with 15 pigs per replicate. Dietary treatments were negative control (NC, basal diet without antimicrobial), positive control (PC, basal diet + 1.5 g kg?1 apramycin), basal diet with 40 mg kg?1 AMP‐P5 (P5‐40) and basal diet with 60 mg kg?1 AMP‐P5 (P5‐60). Pigs fed the PC or P5‐60 diet showed improved (P < 0.05) overall growth performance, apparent total tract digestibility of dry matter, crude protein and gross energy and reduced (P < 0.05) faecal and intestinal coliforms compared with pigs fed the NC diet. CONCLUSION: The results obtained in this study indicate that dietary supplementation with 60 mg kg?1 AMP‐P5 has the potential to improve the growth performance and apparent total tract digestibility of nutrients and reduce coliforms in weanling pigs. © 2012 Society of Chemical Industry  相似文献   
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In this cross-sectional study, the principles of a technology acceptance model were used to identify variables related to the level of Internet usage by older adults. Community-dwelling older adults aged 60–88 years completed a postal questionnaire survey that elicited responses on the use of the Internet. Out of a sample of 592 older adults (236 males and 356 females), 50.7% used the Internet. A multiple linear regression analysis was carried out on the Internet users sample using the self-reported number of hours of Internet usage per week as the dependent variable. The results indicated that attitude toward using the Internet and good health status were statistically significant predictors of the level of Internet usage. A second multiple regression analysis using Internet activity as the dependent variable showed that attitude, usefulness, good health, and gender (males) were significant predictor variables.  相似文献   
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This paper presents and discusses issues relevant to solidification of a chosen lead-free solder, the eutectic Sn-3.5%Ag, and its composite counterparts. Direct temperature recordings for the no-clean solder paste during the simulated reflow process revealed a significant amount of undercooling to occur prior to the initiation of solidification of the eutectic Sn-3.5%Ag solder, which is 6.5 °C, and for the composite counterparts, it is dependent on the percentage of copper nanopowder. Temperature recordings revealed the same temperature level of 221 °C for both melting (from solid to liquid) and final solidification (after recalescence) of the Sn-3.5%Ag solder. Addition of copper nanoparticles was observed to have no appreciable influence on melting temperature of the composite solder. However, it does influence solidification of the composite solder. The addition of 0.5 wt.% copper nanoparticles lowered the solidification temperature to 219.5 °C, while addition of 1.0 wt.% copper nanoparticles lowered the solidification temperature to 217.5 °C, which is close to the melting point of the ternary eutectic Sn-Ag-Cu solder alloy, Sn-3.7Ag-0.9Cu. This indicates the copper nanoparticles are completely dissolved in the eutectic Sn-3.5%Ag solder and precipitate as the Cu6Sn5, which reinforces the eutectic solder. Optical microscopy observations revealed the addition of 1.0 wt.% of copper nanoparticles to the Sn-3.5%Ag solder results in the formation and presence of the intermetallic compound Cu6Sn5. These particles are polygonal in morphology and dispersed randomly through the solder matrix. Addition of microsized copper particles cannot completely dissolve in the eutectic solder and projects a sunflower morphology with the solid copper particle surrounded by the Cu6Sn5 intermetallic compound coupled with residual porosity present in the solder sample. Microhardness measurements revealed the addition of copper nanopowder to the eutectic Sn-3.5%Ag solder resulted in higher hardness.  相似文献   
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The development of biophysical systems that enable an understanding of the structure and ligand‐binding properties of G‐quadruplex (GQ)‐forming nucleic acid sequences in cells or models that mimic the cellular environment would be highly beneficial in advancing GQ‐directed therapeutic strategies. Herein, the establishment of a biophysical platform to investigate the structure and recognition properties of human telomeric (H‐Telo) DNA and RNA repeats in a cell‐like confined environment by using conformation‐sensitive fluorescent nucleoside probes and a widely used cellular model, bis(2‐ethylhexyl) sodium sulfosuccinate reverse micelles (RMs), is described. The 2′‐deoxy and ribonucleoside probes, composed of a 5‐benzofuran uracil base analogue, faithfully report the aqueous micellar core through changes in their fluorescence properties. The nucleoside probes incorporated into different loops of H‐Telo DNA and RNA oligonucleotide repeats are minimally perturbing and photophysically signal the formation of respective GQ structures in both aqueous buffer and RMs. Furthermore, these sensors enable a direct comparison of the binding affinity of a ligand to H‐Telo DNA and RNA GQ structures in the bulk and confined environment of RMs. These results demonstrate that this combination of a GQ nucleoside probe and easy‐to‐handle RMs could provide new opportunities to study and devise screening‐compatible assays in a cell‐like environment to discover GQ binders of clinical potential.  相似文献   
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The influence of ultrathin Au cluster films on the growth of para-hexaphenyl (p-6P) fibres is investigated. Whereas p-6P at elevated temperatures forms long, mutually parallel fibres on plain mica, these fibres become shorter but taller on Au covered mica, up to a Au film thickness of approximately 8?nm. The degree to which fibres are mutually parallel decreases with increasing Au thickness. For thicker Au films the length of the fibres increases again, and their morphology changes from flat to faceted; for Au film thicknesses above 20?nm, fibre networks are formed. The spectroscopic properties of the fibres are not modified by the Au layer, enabling independent control of the fibre morphology by means of the intermediate metallic layer.  相似文献   
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