Effects of Switching Angle Phase Shift on PWM Techniques

The behavior of some well-known pulsewidth modulation (PWM) techniques is investigated under perturbation conditions of power semiconductor gating signals. An evaluation of different PWM techniques is performed considering the effect of PWM timing errors on the output spectra of switch-mode converters.     

An Adversarial Neuro-Tensorial Approach for Learning Disentangled Representations

International Journal of Computer Vision - Several factors contribute to the appearance of an object in a visual scene, including pose, illumination, and deformation, among others. Each factor...     

Analysing software prefetching opportunities in hardware transactional memory

The Journal of Supercomputing - Hardware transactional memory emerged to make parallel programming more accessible. However, the performance pitfall of this technique is squashing speculatively...     

Focussed crawling of environmental Web resources based on the combination of multimedia evidence

Focussed crawlers enable the automatic discovery of Web resources about a given topic by automatically navigating the Web link structure and selecting the hyperlinks to follow by estimating their relevance to the topic based on evidence obtained from the already downloaded pages. This work proposes a classifier-guided focussed crawling approach that estimates the relevance of a hyperlink to an unvisited Web resource based on the combination of textual evidence representing its local context, namely the textual content appearing in its vicinity in the parent page, with visual evidence associated with its global context, namely the presence of images relevant to the topic within the parent page. The proposed focussed crawling approach is applied towards the discovery of environmental Web resources that provide air quality measurements and forecasts, since such measurements (and particularly the forecasts) are not only provided in textual form, but are also commonly encoded as multimedia, mainly in the form of heatmaps. Our evaluation experiments indicate the effectiveness of incorporating visual evidence in the link selection process applied by the focussed crawler over the use of textual features alone, particularly in conjunction with hyperlink exploration strategies that allow for the discovery of highly relevant pages that lie behind apparently irrelevant ones.     

Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1-iddm Rat,an Animal Model of Human Type 1 Diabetes

The LEW.1AR1-iddm rat is an animal model of human type 1 diabetes (T1D). Previously, we have shown that combination with anti-TCR/anti-TNF-α antibody-based therapy re-established normoglycemia and increased proteinic arginine-dimethylation in the spleen, yet not in the pancreas. High blood glucose is often associated with elevated formation of advanced glycation end-products (AGEs) which act via their receptor (RAGE). Both anti-TCR and anti-TNF-α are inhibitors of RAGE. The aim of the present work was to investigate potential biochemical changes of anti-TCR/anti-TNF-α therapy in the LEW.1AR1-iddm rat. We determined by stable-isotope dilution gas chromatography-mass spectrometry (GC-MS) the content of free and proteinic AGEs and the N^ε-monomethylation of lysine (Lys) residues in proteins of pancreas, kidney, liver, spleen and lymph nodes of normoglycemic control (ngCo, n = 6), acute diabetic (acT1D, n = 6), chronic diabetic (chT1D, n = 4), and cured (cuT1D, n = 4) rats after anti-TCR/anti-TNF-α therapy. Analyzed biomarkers included Lys and its metabolites N^ε-carboxymethyl lysine (CML), furosine and N^ε-monomethyl lysine (MML). Other amino acids were also determined. Statistical methods including ANOVA, principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) were used to evaluate the effects. Most statistical differences between the study groups were observed for spleen, pancreas and kidney, with liver and lymph nodes showing no such differences. In the pancreas, the groups differed with respect to proteinic furosine (p = 0.0289) and free CML (p = 0.0023). In the kidneys, the groups differed with respect to proteinic furosine (p = 0.0076) and CML (p = 0.0270). In the spleen, group differences were found for proteinic furosine (p = 0.0114) and free furosine (p = 0.0368), as well as for proteinic CML (p = 0.0502) and proteinic MML (p = 0.0191). The acT1D rats had lower furosine, CML and MML levels in the spleen than the rats in all other groups. This observation corresponds to the lower citrullination levels previously measured in these rats. PCA revealed diametric associations between PC1 and PC2 for spleen (r = −0.8271, p < 0.0001) compared to pancreas (r = 0.5805, p = 0.0073) and kidney (r = 0.8692, p < 0.0001). These findings underscore the importance of the spleen in this animal model of human T1D. OPLS-DA showed that in total sixteen amino acids differed in the experimental groups.     

The Menpo Benchmark for Multi-pose 2D and 3D Facial Landmark Localisation and Tracking

International Journal of Computer Vision - In this article, we present the Menpo 2D and Menpo 3D benchmarks, two new datasets for multi-pose 2D and 3D facial landmark localisation and tracking. In...     

Atomistic simulations of cavitation in a model polyethylene network

A molecular-level understanding of cavitation in polymer networks upon imposition of mechanical stress is still lacking. Molecular Dynamics simulations of crosslinked amorphous Polyethylene (PE) were conducted in order to study cavitation as a function of the prevailing stress. We first show that the characteristic relaxation times related to tube confinement and chain connectivity can be obtained by examining the mean square displacement of middle chain monomers. Then, we present a methodology for predicting the cavitation strength and understanding its dependence on cohesive interactions and entropic elasticity. Our simulations show that experimental observations and predictions of continuum mechanics analysis, which relate the critical stress for cavitation to the Young’s modulus of the rubber, are in agreement with the observed tensile triaxial stress below which a pre-existing cavity cannot survive in a cavitated sample.     

Accurate and large-scale privacy-preserving data mining using the election paradigm

With the proliferation of the Web and ICT technologies there have been concerns about the handling and use of sensitive information by data mining systems. Recent research has focused on distributed environments where the participants in the system may also be mutually mistrustful. In this paper we discuss the design and security requirements for large-scale privacy-preserving data mining (PPDM) systems in a fully distributed setting, where each client possesses its own records of private data. To this end we argue in favor of using some well-known cryptographic primitives, borrowed from the literature on Internet elections. More specifically, our framework is based on the classical homomorphic election model, and particularly on an extension for supporting multi-candidate elections. We also review a recent scheme [Z. Yang, S. Zhong, R.N. Wright, Privacy-preserving classification of customer data without loss of accuracy, in: SDM’ 2005 SIAM International Conference on Data Mining, 2005] which was the first scheme that used the homomorphic encryption primitive for PPDM in the fully distributed setting. Finally, we show how our approach can be used as a building block to obtain Random Forests classification with enhanced prediction performance.