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11.
Announcement
EGIS'92 Third European Conference on Geographical Information Systems at the Park Hilton in Munich Germany, March 23–26, 1992 相似文献12.
Hossein Derakhshankhah Rana Jahanban-Esfahlan Somayeh Vandghanooni Sattar Akbari-Nakhjavani Bakhshali Massoumi Babak Haghshenas Aram Rezaei Amir Farnudiyan-Habibi Hadi Samadian Mehdi Jaymand 《应用聚合物科学杂志》2021,138(24):50578
Gelatin (Gel)-based pH- and thermal-responsive magnetic hydrogels (MH-1 and MH-2) were designed and developed as novel drug delivery systems (DDSs) for cancer chemo/hyperthermia therapy. For this goal, Gel was functionalized with methacrylic anhydride (GelMA), and then copolymerized with (2-dimethylaminoethyl) methacrylate (DMAEMA) monomer in the presence of methacrylate-end capped magnetic nanoparticles (MNPs) as well as triethylene glycol dimethacrylate (TEGDMA; as crosslinker). Afterward, a thiol-end capped poly(N-isopropylacrylamide) (PNIPAAm-SH) was synthesized through an atom transfer radical polymerization technique, and then attached onto the hydrogel through “thiol-ene” click grafting. The preliminary performances of developed MHs for chemo/hyperthermia therapy of human breast cancer was investigated through the loading of doxorubicin hydrochloride (Dox) as an anticancer agent followed by cytotoxicity measurement of drug-loaded DDSs using MTT assay by both chemo- and chemo/hyperthermia-therapies. Owing to porous morphologies of the fabricated magnetic hydrogels according to scanning electron microscopy images and strong physicochemical interactions (e.g., hydrogen bonding) the drug loading capacities of the MH-1 and MH-2 were obtained as 72 ± 1.4 and 77 ± 1.8, respectively. The DDSs exhibited acceptable pH- and thermal-triggered drug release behaviors. The MTT assay results revealed that the combination of hyperthermia therapy and chemotherapy has synergic effect on the anticancer activities of the developed DDSs. 相似文献
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Lung cancer is one of the deadliest diseases in the world. Non‐small cell lung cancer (NSCLC) is the most common and dangerous type of lung cancer. Despite the fact that NSCLC is preventable and curable for some cases if diagnosed at early stages, the vast majority of patients are diagnosed very late. Furthermore, NSCLC usually recurs sometime after treatment. Therefore, it is of paramount importance to predict NSCLC recurrence, so that specific and suitable treatments can be sought. Nonetheless, conventional methods of predicting cancer recurrence rely solely on histopathology data and predictions are not reliable in many cases. The microarray gene expression (GE) technology provides a promising and reliable way to predict NSCLC recurrence by analysing the GE of sample cells. This study proposes a new model from GE programming to use microarray datasets for NSCLC recurrence prediction. To this end, the authors also propose a hybrid method to rank and select relevant prognostic genes that are related to NSCLC recurrence prediction. The proposed model was evaluated on real NSCLC microarray datasets and compared with other representational models. The results demonstrated the effectiveness of the proposed model.Inspec keywords: lung, cancer, lab‐on‐a‐chip, genetics, patient diagnosisOther keywords: NSCLC recurrence prediction, microarray data, GE programming, nonsmall cell lung cancer, cancer recurrence, histopathology data, microarray gene expression, prognostic genes 相似文献
15.
Different Estimation Methods for Constant Stress Accelerated Life Test under the Family of the Exponentiated Distributions 下载免费PDF全文
Abdallah A. Abdel Ghaly Hanan M. Aly Rana N. Salah 《Quality and Reliability Engineering International》2016,32(3):1095-1108
The Accelerated Life Testing (ALT) has been used for a long time in several fields to obtain information on the reliability of product components and materials under operating conditions in a much shorter time. One of the main purposes of applying ALT is to estimate the failure time functions and reliability performance under normal conditions. This paper concentrates on the estimation procedures under ALT and how to select the best estimation method that gives accurate estimates for the reliability function. For this purpose, different estimation methods are used, such as maximum likelihood, least squares (LS), weighted LS, and probability weighted moment. Moreover, the reliability function under usual conditions is predicted. The estimation procedures are applied under the family of the exponentiated distributions in general, and for the exponentiated inverted Weibull (EIW) as a special case. Numerical analysis including simulated data and a real life data set is conducted to compare the performances between these four methods. It is found that the ML method gives the best results among other estimation methods. Finally, a comparison between the EIW and the Inverted Weibull (IW) distributions based on a real life data set is made using a likelihood ratio test. It is observed that the EIW distribution can provide better fitting than the IW in case of ALT. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
16.
Mostafizur Rahman Rana Erik Upol Biswas Sultan Mahmud Salman Meem Sahel Syeda Sarita Hassan Mahdy Rahman Chowdhury Mahdy 《Advanced Engineering Materials》2023,25(20):2300438
Electromagnetic wideband absorption is still perceived as a critical and formidable challenge to address with an unambiguous photonic absorber. Subwavelength metamaterial (MM) unit cells with unique and controlled features have recently gained considerable interest. However, meta-atoms, generated using a quantum-inspired pattern distribution, are underwhelming in existing literature to design photonic absorbers and their potential application to manufacture solar sails is still quite uncommon. In this article, to create a flexible, polarization-insensitive, ultrathin, and broadband MM absorber, quantum interference pattern-inspired design is utilized. Herein, a novel approach to fabricating solar sails for the space exploration incorporates the proposed broadband photonic absorber rather than conventional reflectors. The quantum-inspired meta-absorber (QIMA) exhibits an absorption of over 91% for the visible domain, i.e., 380–800 nm under a conventional plane-polarized source. It is shown in the study that broadband absorbers are almost equivalent to excellent reflectors to design the solar sails in terms of the time-averaged force calculated by utilizing the Maxwell stress tensor method. Thus, the QIMA has the potential to be a viable alternative to reflectors in the design of futuristic solar sails for space exploration. The interference theory model is also utilized to assure the dependability of calculated data, and additionally, the standard AM1.5 solar spectrum is utilized to demonstrate the QIMA's solar-harvesting potentiality. 相似文献
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Sulphur dioxide loadings over megacity Lahore (Pakistan) and adjoining region of Indo-Gangetic Basin
Zia ul-Haq Salman Tariq Muhammad Ali Khalid Mahmood Asim Daud Rana 《International journal of remote sensing》2016,37(13):3021-3041
This article presents spatial and temporal variations of planetary boundary layer (PBL) sulphur dioxide (SO2) over megacity Lahore and adjoining region, a typical representative area in the Indo-Gangetic Basin (IGB) largely influenced by transported volcanic SO2 from Africa, Middle East, and southern Europe, by using data retrieved from satellite-based Ozone Monitoring Instrument (OMI) during October 2004–September 2015. We find a positive trend of 2.4% per year (slope 0.01 ± 0.005 with y-intercept 0.35 ± 0.03 Dobson Unit (DU), correlation coefficient r = 0.55 and 2-tailed p-value at 0.1) of OMI-SO2 column with the average value of 0.4 ± 0.05 DU. Strong seasonality of OMI-SO2 column is observed over the region linked with local meteorology, patterns of anthropogenic emissions, crop residue burning, and vegetation cover. There exists a seasonal high value in winter 0.56 ± 0.24 DU with a peak in December 0.67 ± 0.26 DU. The seasonal lowest value is observed to be 0.29 ± 0.11 DU in wet summer with minimum value in July 0.25 ± 0.06 DU. High growth rates of OMI-SO2 column over the study region have been observed in January, June, October, and December ranging from 5.7% to 11.6% per year. Satellite data show elevated OMI-SO2 columns in 2007, 2008, 2011, and 2012 largely contributed by trans-boundary volcanic SO2. A detailed analysis of volcanic SO2 transported from Africa and Middle East (Jabal Al-Tair, Dalaffilla, and Nabro volcanoes) over the study area is presented. Air mass trajectories suggest the presence of long-range transported volcanic SO2 at high altitude levels over Lahore and IGB region during the volcanic episodes. The SO2 enhancements in PBL during winter season are generally due to significant vertical downdraft of high-altitude volcanic SO2. For the first time, we present significant influence of volcanic SO2 from southern Europe (Mt. Etna volcano) reaching over the study area. Daily mean OMI-SO2 levels up to 21.4, 10.0, 5.6, and 2.4 DU have been noticed due to the eruptions from Dalaffilla, Mt. Etna, Nabro, and Jabal Al-Tair volcanoes, respectively. 相似文献
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20.
Service discovery is a critical task in distributed computing architectures for finding a particular service instance. Semantic
annotations of services help to enrich the service discovery process. Semantic registries are an important component for the
discovery of services and they allow for semantic interoperability through ontology-based query formulation and dynamic mapping
of terminologies between system domains. This paper evaluates two semantic registries—OWLJessKB implementation and instanceStore—to
determine the suitability of these with regards to the query response time and the overall scalability for use in mathematical
services. Mathematical ontologies from the MONET project are used to undertake comparison. The results demonstrate that the
performance of registries may be compared across two axes: (1) time to initialize (i.e. time to load an initial ontology into
memory); (2) time to query (i.e. time to reason with an ontology loaded into memory). 相似文献