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91.
92.
Sanghoon Park Roxana Shabani Mark Schumacher Yoon-Seoung Kim Young Min Bae Kyeong-Hee Lee Hyoung Jin Cho 《Microsystem Technologies》2016,22(8):2077-2085
Miniaturized on-chip blood separators have a great value for point-of-care diagnosis. In our work, a combined design strategy—microfiltration, sedimentation in a retarded flow, and wetting contrast—was taken to overcome the known limitations of on-chip blood separators. Our microfluidic chip consists of a polydimethylsiloxane micropillar array and an etched glass with microchannel branches. The red blood cells are significantly slowed and gradually settled down due to micropillars and enlarged dimension of a chamber. An etched glass microchannel allows the extraction of blood plasma exclusively due to the capillary effect. The fabricated microfluidic device can separate blood plasma from a whole blood sample without any external driving force or dilution. The measured plasma separation efficiency was close to 100 % from human whole blood. Autonomous on-chip separation and collection of blood plasma was demonstrated. 相似文献
93.
Yunji Jung Yulong Xi Seoungjae Cho Wei Song Simon Fong Kyungeun Cho 《Multimedia Tools and Applications》2017,76(9):11429-11447
The objective of this study is to solve the problem of user data not being precisely received from sensors because of sensing region limitations in invoked reality (IR) space, distortion of colors or patterns by lighting, and blocking or overlapping of a user by other users. The sensing scope range is thus expanded using multiple sensors in the IR space. Moreover, user feature data are accurately identified by user sensing. Specifically, multiple sensors are employed when not all of user data are sensed because they overlap with data of other users. In the proposed approach, all clients share the user feature data from multiple sensors. Accordingly, each client recognizes that the user is the same individual on the basis of the shared data. Furthermore, the identification accuracy is improved by identifying the user features based on colors and patterns that are less affected by lighting. Therefore, accurate identification of the user feature data is enabled, even under lighting changes. The proposed system was implemented based on system performance analysis standards. The practicality and system performance in identifying the same person using the proposed method were verified through an experiment. 相似文献
94.
Stephen G. McGill Seung‐Joon Yi Hak Yi Min Sung Ahn Sanghyun Cho Kevin Liu Daniel Sun Bhoram Lee Heejin Jeong Jinwook Huh Dennis Hong Daniel D. Lee 《野外机器人技术杂志》2017,34(4):775-801
This paper describes Team THOR's approach to human‐in‐the‐loop disaster response robotics for the 2015 DARPA Robotics Challenge (DRC) Finals. Under the duress of unpredictable networking and terrain, fluid operator interactions and dynamic disturbance rejection become major concerns for effective teleoperation. We present a humanoid robot designed to effectively traverse a disaster environment while allowing for a wide range of manipulation abilities. To complement the robot hardware, a hierarchical software foundation implements network strategies that provide real‐time feedback to an operator under restricted bandwidth using layered user interfaces. Our strategy for humanoid locomotion includes a backward‐facing knee configuration paired with specialized toe and heel lifting strategies that allow the robot to traverse difficult surfaces while rejecting external perturbations. With an upper body planner that encodes operator preferences, predictable motion plans are executed in unforeseen circumstances. These plans are critical for manipulation in unknown environments. Our approach was validated during the DRC Finals competition, where Team THOR scored three points in 18 min of operation time, and the results are presented along with an analysis of each task. 相似文献
95.
Cho Dong-Hyun Lee Donghun Bang Hyochoong Kim Hae-Dong 《International Journal of Control, Automation and Systems》2017,15(4):1729-1737
International Journal of Control, Automation and Systems - In this research, a new control law for the trajectory correction maneuver (TCM) is proposed for a spacecraft assumed to be actuated by a... 相似文献
96.
L. Beirão da Veiga A. Buffa D. Cho G. Sangalli 《Computer Methods in Applied Mechanics and Engineering》2011,200(21-22):1787-1803
We develop optimal approximation estimates for T-splines in the case of geometries obtained by gluing two standard tensor product patches. We derive results both for the T-spline space in the parametric domain and the mapped T-NURBS in the physical one. A set of numerical tests in complete accordance with the theoretical developments is also presented. 相似文献
97.
Kim D Cho CH Cho Y Ryu J Bhak J Kim DS 《Journal of molecular graphics & modelling》2008,26(7):1104-1112
Proteins consist of atoms. Given a protein, the automatic recognition of depressed regions, called pockets, on the surface of proteins is important for protein-ligand docking and facilitates fast development of new drugs. Recently, computational approaches have emerged for recognizing pockets from the geometrical point of view. Presented in this paper is a geometric method for the pocket recognition which is based on the Voronoi diagram for atoms. Given a Voronoi diagram, the proposed algorithm transforms the atomic structure to meshes which contain the information of the proximity among atoms, and then recognizes depressions on the surface of a protein using the meshes. 相似文献
98.
Kyung-Joong Kim Sung-Bae Cho 《Evolutionary Computation, IEEE Transactions on》2008,12(3):377-388
In general, the analysis of microarray data requires two steps: feature selection and classification. From a variety of feature selection methods and classifiers, it is difficult to find optimal ensembles composed of any feature-classifier pairs. This paper proposes a novel method based on the evolutionary algorithm (EA) to form sophisticated ensembles of features and classifiers that can be used to obtain high classification performance. In spite of the exponential number of possible ensembles of individual feature-classifier pairs, an EA can produce the best ensemble in a reasonable amount of time. The chromosome is encoded with real values to decide the weight for each feature-classifier pair in an ensemble. Experimental results with two well-known microarray datasets in terms of time and classification rate indicate that the proposed method produces ensembles that are superior to individual classifiers, as well as other ensembles optimized by random and greedy strategies. 相似文献
99.
Dynamic planning model for determining cutting parameters using neural networks in feature-based process planning 总被引:1,自引:0,他引:1
Jaekoo Joo Gwang-Rim Yi Hyunbo Cho Yong-Sun Choi 《Journal of Intelligent Manufacturing》2001,12(1):13-29
Although feature-based computer-aided process planning plays a vital role in automating and integrating design and manufacturing for efficient production, its off-line properties prohibit the shop floor controllers from rapidly coping with unexpected production errors. The objective of the paper is to suggest a neural network-based dynamic planning model, by which the shop floor controllers determine cutting parameters in real-time based on shop floor status. At off-line is the dynamic planning model constructed as a neural network form, and then embedded into each removal feature. The dynamic planning model will be executed by the shop floor controllers to determine the cutting parameters. A prototype system is constructed to validate whether the dynamic planning model is capable of determining dynamically and efficiently the cutting parameters for a particular set of shop operating factors. Owing to the dynamic planning model, the shop floor controller will increase flexibility and robustness by rapidly and adaptively determining the cutting parameters in unexpected errors occurring. 相似文献
100.
Cho EH Kim MR Kim HJ Lee DY Kim PK Choi KM Ryu OH Kim CW 《Proteomics. Clinical applications》2007,1(4):352-361
Diabetic nephropathy (DN) is a serious kidney complication of diabetes, and constitutes the leading cause of end-stage renal disease. The earliest clinical evidence of DN is microalbuminuria, a term which refers to the appearance of small but abnormal amounts of albumin in the urine. However, screening methods for DN, such as biomarker assays, are yet to be developed for type 2 DN. In the present study, in an attempt to identify the biomarkers for initial diagnoses of type 2 DN, the protein profiles of human sera collected from 30 microalbuminuric type 2 diabetic patients were compared with those collected from 30 normoalbuminuric type 2 diabetic patients, via 2-DE. As a result, a total of 18 spots were determined to have different protein levels in the microalbuminuric patients. Twelve spots had lower protein levels of approximately 50%, and the other six had higher levels of approximately 100-300% as compared to the spots of normoalbuminuric patients. These spots were identified with ESI-Q-TOF (ESI-quadrupole-TOF) MS. Among the identified proteins, vitamin D-binding protein (DBP) and pigment epithelium-derived factor (PEDF) were verified by Western blotting. The results of this study indicate that the DBP may be employed as diagnostic and monitoring biomarkers of type 2 DN, contingent on further study into the matter. 相似文献