Organizing for innovation does not present itself as a straightforward exercise. The complexities entailed when implementing an innovation strategy can be related directly to the multitude of objectives it comprises. Recently, several scholars have advanced the notions of semi‐ or quasi‐structures and ambidextrous organizations to handle these multiple requirements. These organizational forms imply the simultaneous presence of different activities, exhibiting differences in technology and market maturation. As a consequence, financial returns will reflect this diversified resource allocation pattern. Moreover, as higher levels of complexity are being introduced; ambidextrous organizations will encounter additional, organizational, costs. Compared to organizations that focus on the most profitable part of the portfolio, ambidextrous organizations – ceteris paribus – tend to be inferior in terms of financial returns. Within this contribution we explore under which conditions ambidextrous organizations can outperform focused firms; considered a prerequisite for their sustainability. In order to do so, we develop an analytical framework depicting the differential value dynamics, focused and ambidextrous firms can enact. Our findings reveal the relevancy of adopting extended time frames as well as introducing interface management practices aimed at cross‐fertilization. Finally, the synergetic potential of (underlying) technologies comes to the forefront as necessary in order for ambidextrous organizations to become sustainable. 相似文献
Preschool children are more susceptible to misleading postevent information than are older children and adults. One reason for young children's suggestibility is their failure to monitor the source of their memories, as in, for example, discriminating whether an event was seen live versus on television. The authors investigated whether source-monitoring training would decrease preschoolers' suggestibility. Thirty-six 3-4-year-olds observed target live and video events and were then given source-monitoring or recognition (control) training on nontarget events. Following training, all children answered 24 misleading and nonmisleading target-event questions. Children given source-monitoring training were more accurate than control group children in response to misleading and nonmisleading yes-no questions and in response to nonmisleading, open-ended questions. Implications for strategy development, dual representation, and child witness interviewing are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
Palladium(II) acetate in association with secondary phosphine oxides provides an efficient catalytic system for [2+1] cycloadditions starting from oxanorbornene derivatives and tertiary propargyl esters giving rise to vinylidenecyclopropanes. This reaction is specific to bidentate phosphinito–phosphinous acid ligands generated from secondary phosphine oxides. The [2+1] cycloaddition was found broad in scope with a high tolerance to various functional groups. Moreover, vinylidenecyclopropanes were straightforwardly converted into oxabicyclo[3.2.1]oct‐2‐ene derivatives through a palladium‐catalyzed ring‐expansion. Finally, the oxa bridge cleavage of oxatricyclic compounds yields functionalized 7‐membered carbocycles.
Communication networks, whether they are wired or wireless, have traditionally been assumed to be connected at least most
of the time. However, emerging applications such as emergency response, special operations, smart environments, VANETs, etc.
coupled with node heterogeneity and volatile links (e.g. due to wireless propagation phenomena and node mobility) will likely
change the typical conditions under which networks operate. In fact, in such scenarios, networks may be mostly disconnected,
i.e., most of the time, end-to-end paths connecting every node pair do not exist. To cope with frequent, long-lived disconnections,
opportunistic routing techniques have been proposed in which, at every hop, a node decides whether it should forward or store-and-carry a message.
Despite a growing number of such proposals, there still exists little consensus on the most suitable routing algorithm(s)
in this context. One of the reasons is the large diversity of emerging wireless applications and networks exhibiting such
“episodic” connectivity. These networks often have very different characteristics and requirements, making it very difficult,
if not impossible, to design a routing solution that fits all. In this paper, we first break up existing routing strategies
into a small number of common and tunable routing modules (e.g. message replication, coding, etc.), and then show how and when a given routing module should be used, depending on the set of network characteristics exhibited by the wireless application. We further attempt to create a taxonomy for intermittently connected networks. We
try to identify generic network characteristics that are relevant to the routing process (e.g., network density, node heterogeneity, mobility patterns) and dissect different
“challenged” wireless networks or applications based on these characteristics. Our goal is to identify a set of useful design guidelines that will enable one to choose an appropriate routing protocol for the application or network in hand. Finally, to demonstrate
the utility of our approach, we take up some case studies of challenged wireless networks, and validate some of our routing
design principles using simulations. 相似文献
A mutant of D ‐fructose‐6‐phosphate aldolase (FSA) of Escherichia coli, FSA A129S, with improved catalytic efficiency towards dihydroxyacetone (DHA), the donor substrate in aldol addition reactions, was explored for synthetic applications. The kcat/KM value for DHA was 17‐fold higher with FSA A129S than that with FSA wild type (FSA wt). On the other hand, for hydroxyacetone as donor substrate FSA A129S was found to be 3.5‐fold less efficient than FSA wt. Furthermore, FSA A129S also accepted glycolaldehyde (GA) as donor substrate with 3.3‐fold lower affinity than FSA wt. This differential selectivity of both FSA wt and FSA A129S for GA makes them complementary biocatalysts allowing a control over donor and acceptor roles, which is particularly useful in carboligation multi‐step cascade synthesis of polyhydroxylated complex compounds. Production of the mutant protein was also improved for its convenient use in synthesis. Several carbohydrates and nitrocyclitols were efficiently prepared, demonstrating the versatile potential of FSA A129S as biocatalyst in organic synthesis. 相似文献
A successful prevention of renal diseases induced by occupational exposure to lead (Pb) and/or cadmium (Cd) largely relies on the capability to detect nephrotoxic effects at a stage when they are still reversible or at least not yet compromising renal function. Hence, the aim of this cross-sectional study was to evaluate the usefulness of a set of early biological markers of oxidative stress or nephrotoxicity for the biomonitoring of workers occupationally exposed to Pb and/or Cd in a non-ferrous metal smelter, and gender, age, socioeconomic status, smoking habits, and drug use-matched control individuals. In exposed subjects, mean levels of Pb in blood and urine were also 387.1+/-99.1 microg Pb/L (1.868+/-0.478 micromol Pb/L) and 217.7+/-117.7 microg Pb/g creatinine (1.051+/-0.568 micromol Pb/g creatinine), and mean levels of Cd in blood and urine were 3.26+/-2.11 microg Cd/L (0.029+/-0.019 micromol Cd/L) and 2.51+/-1.89 microg Cd/g creatinine (0.022+/-0.017 micromol Cd/g creatinine), suggesting thereby relatively low occupational exposure levels. Statistically significant variations in zinc protoporphyrin, malondialdehyde, retinol binding protein, alpha-glutathione S-transferase, and urinary protein levels were reported between the two groups, and were closely correlated with Pb and/or Cd exposure levels. Variations in alphaGST levels were closely associated with Pb exposure. Taken together, these results suggest the use of alpha-glutathione S-transferase excretion in urine as a hallmark of early changes in the proximal tubular integrity. 相似文献
A new hybrid electrochemical capacitor based on an activated carbon negative electrode, lead dioxide thin film and nanowire array positive electrode with an electrolyte made of a lead salt dissolved in methanesulfonic acid was investigated. It is shown that the maximum energy density and specific capacity of the C/PbO2 nanowire system increase during the first 50 cycles before reaching their maximum values, which are 29 Wh kg−1 and 34 F g−1, respectively, at a current density of 10 mA cm−2 and a depth of discharge (positive active electrode material) of 3.8%, that corresponds to a 22C rate. This is 7–8 times higher than the corresponding maximum values reached with a C/PbO2 thin film cell operated in the same conditions. After an initial activation period, the performances of the C/PbO2 nanowire system stay constant and do not show any sign of degradation during more than 5000 cycles. For comparison, the C/PbO2 thin film system exhibits a 50% decrease of its performances in similar conditions. 相似文献
The assessment of the exposure to electromagnetic waves is nowadays a key question. Dealing with the relationship between exposure and incident field, most of previous investigations have been performed with a single plane wave. Realistic exposure in the far field can be modeled as multiple plane waves with random direction of arrival, random amplitude, and random phase. This paper, based on numerical investigations, studies the whole body specific absorption rate (SAR) linked to the exposure induced by five random plane waves having uniformly distributed angles of arrival in the horizontal plane, log-normal distributed amplitudes, and uniformly distributed phases. A first result shows that this random heterogeneous exposure generates maximal variations of ??25% for the whole body specific absorption. An important observation is that the exposure to a single plane wave arriving face to the body, used for the guidelines, does not constitute the worst case. We propose a surrogate model to assess the distribution of the whole body SAR in the case of an exposure to multiple plane waves. For a sample of 30 values of whole body SAR induced by five plane waves at 2.4?GHz, this simple approach, considering the resulting SAR as the sum of the SAR induced by each isolated plane wave, leads to an estimated distribution of whole body SAR following the real distribution with a p value of 76% according to the Kolmogorov statistical test. 相似文献