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101.
102.
Min-Hua Chen Tomohiko Yoshioka Toshiyuki Ikoma Nobutaka Hanagata 《Science and Technology of Advanced Materials》2014,15(5)
Theranostic nanoparticles currently have been regarded as an emerging concept of ‘personalized medicine’ with diagnostic and therapeutic dual-functions. Eu3+ doped hydroxyapatite (HAp) has been regarded as a promising fluorescent probe for in vivo imaging applications. Additionally, substitution of Ca2+ with Fe3+ in HAp crystal may endow the capability of producing heat upon exposure to a magnetic field. Here we report a preliminary study of doping mechanism and photoluminescence of Eu3+ and Fe3+ doped HAp nanoparticles (Eu/Fe:HAp). HAp with varied concentration of Eu3+ and Fe3+ doping are presented as Eu(10 mol%):HAp, Eu(7 mol%)-Fe(3 mol%):HAp, Eu(5 mol%)-Fe(5 mol%):HAp, Eu(3 mol%)-Fe(7 mol%):HAp, and Fe(10 mol%):HAp in the study. The results showed that the HAp particles, in nano-size with rod-like morphology, were successfully doped with Eu3+ and Fe3+, and the particles can be well suspended in cell culture medium. Photoluminescence analysis revealed that particles have prominent emissions at 536 nm, 590 nm, 615 nm, 650 nm and 695 nm upon excitation at a wavelength of 397 nm. Moreover, these Eu/Fe:HAp nanoparticles belonged to B-type carbonated HAp, which has been considered an effective biodegradable and biocompatible drug/gene carrier in biological applications. 相似文献
103.
Per Henningsson Dirk Michaelis Toshiyuki Nakata Daniel Schanz Reinhard Geisler Andreas Schr?der Richard J. Bomphrey 《Journal of the Royal Society Interface》2015,12(108)
Particle image velocimetry has been the preferred experimental technique with which to study the aerodynamics of animal flight for over a decade. In that time, hardware has become more accessible and the software has progressed from the acquisition of planes through the flow field to the reconstruction of small volumetric measurements. Until now, it has not been possible to capture large volumes that incorporate the full wavelength of the aerodynamic track left behind during a complete wingbeat cycle. Here, we use a unique apparatus to acquire the first instantaneous wake volume of a flying animal''s entire wingbeat. We confirm the presence of wake deformation behind desert locusts and quantify the effect of that deformation on estimates of aerodynamic force and the efficiency of lift generation. We present previously undescribed vortex wake phenomena, including entrainment around the wing-tip vortices of a set of secondary vortices borne of Kelvin–Helmholtz instability in the shear layer behind the flapping wings. 相似文献
104.
105.
高温流化床的流化特性及结焦非流化行为 总被引:3,自引:0,他引:3
在 8 0 mm× 30 mm和 80 mm× 10 mm石英流化床中 ,以低温粘结的高密度聚乙烯和聚丙烯 ,高温粘结的玻璃珠为实验物料 ,研究了高温流化床的流化特性及高温下物料结焦产生的非流化行为。结果表明 ,在本文实验条件下 ,Geldart A、B类高温表面粘结物料 ,床层温度小于其最小粘结温度时 ,床层温度增大 ,颗粒的最小流化速度减小 ;Geldart D类高温表面粘结物料的最小流化速度随温度增加而增大。得出了不同温度下颗粒最小流化速度预测式。床层温度大于最小粘结温度时 ,流化床需在较高的表观气速下才能保持流化 ,床层温度愈高床层流化所需的表观气速越大。研究同时发现 ,颗粒物料的粒径减小 ,流化颗粒的最小粘结温度减小。 相似文献
106.
Maki D Ishii T Sato F Kato Y Yamamoto T Iida T 《Radiation protection dosimetry》2011,144(1-4):222-225
A confocal laser microscope system was developed for the measurement of radiophotoluminescence (RPL) photons emitted from a minute alpha-ray-irradiated area in an RPL glass dosemeter. The system was composed mainly of an inverted-type microscope, an ultraviolet laser, an XY movable stage and photon-counting circuits. The photon-counting circuits were effective in the reduction of the background noise level in the measurement of RPL photons. The performance of this microscope system was examined by the observation of standard RPL glass samples irradiated using (241)Am alpha rays. The spatial resolution of this system was ~ 3 μm, and with regard to the sensitivity of this system, a hit of more than four to five alpha rays in unit area produced enough amount of RPL photons to construct the image. 相似文献
107.
Kumaki Y Ogawa M Hirano T Yoshikawa K Iwasawa N Yagi T Hakamata W Oku T Nishio T 《Journal of Bioscience and Bioengineering》2011,111(2):134-139
The chromosomal DNA of the syntrophic thermophile Symbiobacterium thermophilum contains open reading frames of the genes encoding family M42 aminopeptidases, Pep1079, Pep1080, and Pep1081. To characterize these peptidases, the genes were cloned into Escherichia coli and overexpressed. Our experiments using the recombinant proteins confirmed that Pep1079, Pep1080, and Pep1081 are components of arginyl or lysinyl aminopeptidases that require Co2+ for enzymatic activity. Coexistence of Pep1079 and Pep1080 is necessary for expressing high peptidase activity. Pep1081 enhances the activity of Pep1079 and Pep1080. 相似文献
108.
Toshiyuki Yamaguchi Toshitsugu Kobata Shigetoshi Niiyama Takashi Nakamura Akira Yoshida 《Solar Energy Materials & Solar Cells》2003,75(1-2):87-92
Thin films of Cu–In–Ga–Se alloy system with various composition were prepared by thermal crystallization from In/CuInGaSe/In precursor. Electron probe microanalysis and X-ray diffraction study revealed that these samples were assigned to chalcopyrite Cu(In,Ga)Se2 or ordered vacancy compound Cu(In,Ga)2Se3.5. Solar cell with ZnO:Al/i–ZnO/CdS/Cu(In,Ga)Se2/Mo/soda-lime glass substrate structure was fabricated by using thermal crystallization technique, and demonstrated a 9.58% efficiency without AR-coating. 相似文献
109.
Detection of enzymatically generated hydrogen peroxide by metal-based fluorescent probe 总被引:1,自引:0,他引:1
We developed a metal-based fluorescent probe for H(2)O(2) called MBFh1, which has an iron complex as a reaction site for H(2)O(2) and a 3,7-dihydroxyphenoxazine derivative as the fluorescent reporter unit. The iron complex reacts quickly with H(2)O(2) to form oxidants, and then the oxidants convert the closely appended nonfluorescent 3,7-dihydroxyphenoxazine moiety to resorufin in an intramolecular fashion. The quick response to H(2)O(2) allows us to plot the enzymatic evolution of H(2)O(2). A combination of N-acetyl-3,7-dihydroxyphenoxazine and horseradish peroxidase has been frequently used to detect enzymatically generated H(2)O(2), but this method has interference with phenol derivatives. The use of MBFh1 overcomes this drawback. 相似文献
110.