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51.
In this article, the authors assessed job seekers' organizational image beliefs before and after they experienced 3 recruitment media. The authors examined whether perceptions of media richness and credibility were related to improvements in the correspondence between job seekers' image beliefs and firms' projected images. Both media richness and credibility perceptions were associated with correspondence between job seekers' image beliefs and firms' projected images. However, results revealed that richness and credibility perceptions were likely to enhance job seekers' initial beliefs about firms' images when their beliefs were positive but did not diminish job seekers' beliefs about firms' images when their initial impressions were too positive. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
52.
PCI Express技术可提供极快的速度、彻底改变通讯模式的特性已被业界广泛讨论,但很少有人论及PCI Express如何让芯片间进行通讯.在先前一系列PCI Express架构的技术文章中,我们已从虚拟通道的议题,一路探讨到应用与PC架构的领域.然而,连接PCI Express(PCIe)与ExpressCard组件的可编程接口是我们尚未探讨的主题,本文将针对该主题进行深入的探讨. 相似文献
53.
The insoluble organic residues from the hydrogenation of Tasmanites sp. oil shale have been characterized by Curie point pyrolysis combined with gas chromatography and computerized gas chromatography-mass spectrometry. The resulting pyrograms show that very little, if any, hydrogenation of the residues occurs. Rather, the initial step in the sequence is pyrolysis of the residue followed by hydrogenation of the liquid products. Major compounds identified from the pyrograms of the residues include alkene/alkane doublets, mixtures of diterpenoids and mono- di- and triaromatic compounds. Changes in the distribution of these compounds with changes in reaction conditions are discussed. 相似文献
54.
Cools R Robbins TW 《Philosophical transactions. Series A, Mathematical, physical, and engineering sciences》2004,362(1825):2871-2888
A failure to adapt to novel or changing environmental demands is a core feature of a wide variety of neuropsychiatric disorders as well as the normal states of stress and fatigue. We review the neurochemistry of cognitive control, which has been associated primarily with the prefrontal cortex. Many drugs affect the functioning of the prefrontal cortex, but the direction and extent of drug effects vary across individuals and tasks. Apparently paradoxical effects are often observed, where the same medication causes both cognitive enhancement as well as cognitive side effects. We review neurobiological research that is beginning to elucidate the nature of these contrasting effects and the factors underlying the large variability across individuals and behaviours. The work has considerable implications for the understanding of and treatment development for abnormalities such as Parkinson's disease, attention deficit hyperactivity disorder and drug addiction. 相似文献
55.
Chemical force spectroscopy (CFS) is becoming a powerful technique with which to measure intermolecular forces. The prime advantage over other techniques is the ability to map spatial distribution of ligands on the surface. We have used CFS to explore the binding force of a variety of different chiral molecules in order to understand more about the nature of what is a fundamental aspect of chemical biology and of central importance in pharmacology. 相似文献
56.
By its very nature, a large-scale evaluation of client satisfaction with public education using a quantitative approach, places almost impossibly competing demands on the research methodology. This paper reports on the use of a suite of Rasch measurement techniques to meet the competing demands in establishing state-wide benchmarks relating to the School Opinion Survey carried out over 1200 government schools in one state of Australia. Although the evaluation had to establish system-wide representative parent and student benchmarks, meaningful quantitative estimates of client satisfaction had to be provided at the smallest public schools. The final 20-item School Opinion Survey Parent and Student Forms were designed following feedback from the administration of trial forms. Instrument development was monitored by the results of Rasch modeling. The Rasch modeling property of specific objectivity was empirically verified when calculation of identical benchmark estimates resulted from the construction of simulated population proportional samples using sample:population size weightings. 相似文献
57.
Virus Matryoshka: A Bacteriophage Particle—Guided Molecular Assembly Approach to a Monodisperse Model of the Immature Human Immunodeficiency Virus
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Pooja Saxena Li He Andrey Malyutin Siddhartha A. K. Datta Alan Rein Kevin M. Bond Martin F. Jarrold Alessandro Spilotros Dmitri Svergun Trevor Douglas Bogdan Dragnea 《Small (Weinheim an der Bergstrasse, Germany)》2016,12(42):5862-5872
Immature human immunodeficiency virus type 1 (HIV‐1) is approximately spherical, but is constructed from a hexagonal lattice of the Gag protein. As a hexagonal lattice is necessarily flat, the local symmetry cannot be maintained throughout the structure. This geometrical frustration presumably results in bending stress. In natural particles, the stress is relieved by incorporation of packing defects, but the magnitude of this stress and its significance for the particles is not known. In order to control this stress, we have now assembled the Gag protein on a quasi‐spherical template derived from bacteriophage P22. This template is monodisperse in size and electron‐transparent, enabling the use of cryo‐electron microscopy in structural studies. These templated assemblies are far less polydisperse than any previously described virus‐like particles (and, while constructed according to the same lattice as natural particles, contain almost no packing defects). This system gives us the ability to study the relationship between packing defects, curvature and elastic energy, and thermodynamic stability. As Gag is bound to the P22 template by single‐stranded DNA, treatment of the particles with DNase enabled us to determine the intrinsic radius of curvature of a Gag lattice, unconstrained by DNA or a template. We found that this intrinsic radius is far larger than that of a virion or P22‐templated particle. We conclude that Gag is under elastic strain in a particle; this has important implications for the kinetics of shell growth, the stability of the shell, and the type of defects it will assume as it grows. 相似文献
58.
The motivation for this paper is to present an approach for rating the quality of the parameters in a computer-aided design model for use as optimization variables. Parametric Effectiveness is computed as the ratio of change in performance achieved by perturbing the parameters in the optimum way, to the change in performance that would be achieved by allowing the boundary of the model to move without the constraint on shape change enforced by the CAD parameterization. The approach is applied in this paper to optimization based on adjoint shape sensitivity analyses. The derivation of parametric effectiveness is presented for optimization both with and without the constraint of constant volume. In both cases, the movement of the boundary is normalized with respect to a small root mean squared movement of the boundary. The approach can be used to select an initial search direction in parameter space, or to select sets of model parameters which have the greatest ability to improve model performance. The approach is applied to a number of example 2D and 3D FEA and CFD problems. 相似文献
59.
Barbara J. Meyer Brin F. S. Grenyer Trevor Crowe Alice J. Owen Elizabeth M. Grigonis-Deane Peter R. C. Howe 《Lipids》2013,48(9):863-868
The aim of this study was to determine if changes in omega‐3 polyunsaturated fatty acid status following tuna oil supplementation correlated with changes in scores of depression. A total of 95 volunteers receiving treatment for major depression were randomised to consume 8 × 1 g capsules per day of HiDHA (2 g DHA, 0.6 g EPA and 10 mg Vitamin E) or olive oil (placebo) for 16 weeks, whilst undergoing weekly counseling sessions by trained clinical psychologists using a standard empirically validated psychotherapy. Depression status was assessed using the 17 item Hamilton rating scale for depression and the Beck Depression Inventory by a psychodiagnostician who was blind to the treatment. Blood was taken at baseline and 16 weeks (n = 48) for measurement of erythrocyte fatty acids. With HiDHA supplementation, erythrocyte DHA content rose from 4.1 ± 0.2 to 7.9 ± 0.4 % (mean ± SEM, p < 0.001) of total fatty acids but did not change (4.0 ± 0.2 to 4.1 ± 0.2 %) in the olive oil group. The mean changes in scores of depression did not differ significantly between the two groups (?12.2 ± 2.1 for tuna oil and ?14.4 ± 2.3 for olive oil). However, analysis of covariance showed that in the fish oil group there was a significant correlation (r = ?0.51) between the change in erythrocyte DHA and the change in scores of depression (p < 0.05). Further study of the relationship between DHA and depression is warranted. 相似文献
60.
Mark Woh Yuan Lin Sangwon Seo Scott Mahlke Trevor Mudge 《Journal of Signal Processing Systems》2011,63(1):83-94
Commercial and research work in the field of software defined radio (SDR) has produced designs which have been able to deliver
the efficiency and computational power needed to process 3G wireless technologies. Though efficient 3G processing has been
achieved by these designs, next generation 4G SDR technology requires 10–1000x more computational performance but limits the
power budget increase to 2–5x. In this paper, we present a breakdown of the major 4G kernels and analyze two methods of increasing
performance and reducing power consumption. Specifically, we consider the effect of SIMD width and reduction in number of
register file accesses on the performance and energy consumption of a SDR architecture, SODA. We show that by increasing SIMD
width we can gain almost 2–8x performance increase while increasing total energy used by 1–2x for different SIMD widths. We
also show that by reducing SIMD register accesses we can reduce the total energy used by 5–20% for the 4G kernels. 相似文献