A saturated discrete particle model and characteristic-based SPH method in granular materials

Based on the discrete particle model for solid-phase deformation of granular materials consisting of dry particulate assemblages, a discrete particle–continuum model for modelling the coupled hydro-mechanical behaviour in saturated granular materials is developed. The motion of the interstitial fluid is described by two parallel continuum schemes governed by the averaged incompressible N–S equations and Darcy's law, respectively, where the latter one can be regarded as a degraded case of the former. Owing to the merits in both Lagrangian and mesh-free characters, the characteristic-based smoothed particle hydrodynamics (SPH) method is proposed in this paper for modelling pore fluid flows relative to the deformed solid phase that is modelled as packed assemblages of interacting discrete particles. It is assumed that the formulation is Lagrangian with the co-ordinate system transferring with the movement of the solid particles. The assumed continuous fluid field is discretized into a finite set of Lagrangian (material) points with their number equal to that of solid particles situated in the computational domain. An explicit meshless scheme for granular materials with interstitial water is formulated. Numerical results illustrate the capability and performance of the present model in modelling the fluid–solid interaction and deformation in granular materials saturated with water. Copyright © 2007 John Wiley & Sons, Ltd.     

Utility of R0 as a predictor of disease invasion in structured populations

Early theoretical work on disease invasion typically assumed large and well-mixed host populations. Many human and wildlife systems, however, have small groups with limited movement among groups. In these situations, the basic reproductive number, R0, is likely to be a poor predictor of a disease pandemic because it typically does not account for group structure and movement of individuals among groups. We extend recent work by combining the movement of hosts, transmission within groups, recovery from infection and the recruitment of new susceptibles into a stochastic model of disease in a host metapopulation. We focus on how recruitment of susceptibles affects disease invasion and how population structure can affect the frequency of superspreading events (SSEs). We show that the frequency of SSEs may decrease with the reduced movement and the group sizes due to the limited number of susceptible individuals available. Classification tree analysis of the model results illustrates the hierarchical nature of disease invasion in host metapopulations. First, the pathogen must effectively transmit within a group (R0>1), and then the pathogen must persist within a group long enough to allow for movement among the groups. Therefore, the factors affecting disease persistence--such as infectious period, group size and recruitment of new susceptibles--are as important as the local transmission rates in predicting the spread of pathogens across a metapopulation.     

一种基于贝叶斯网络的雷达重频模式识别方法

雷达重频模式指雷达脉冲重复间隔（PRI）的调制样式，重频模式识别对于雷达型号、类别识别具有重要支持作用，但这是一个较困难的过程，一般难以通过单一重频特征完成多种复杂重频模式的自动识别。本文为解决雷达多重频模式自动识别及识别抗噪声干扰问题，针对多种重频模式提取了几种PRI序列特征量（重频特征），然后引入了贝叶斯多网络分类器（BMNClassifier），利用所提取的特征量作为贝叶斯多网络分类器输入节点，通过贝叶斯多网络分类器的概率推理能力来实现雷达重频模式识别。     

iPhone手机影响分析

iPhone的发布在业内引起巨大轰动，这是继iPod之后苹果公司的又一巨作。iPhone的全触摸屏设计、强大的音乐功能对全球手机行业带来了强烈的冲击。分析了iPhone的优缺点，进一步阐述了苹果公司的发展战略，并透析了iPhone对全球手机行业所带来的影响。     

Controlled Synthesis of Various Hollow Cu Nano/MicroStructures via a Novel Reduction Route

Hollow Cu nano/microstructures are prepared by reduction of CuSO₄ · 5 H₂O with glucose by using a mild hydrothermal process. The X‐ray powder diffraction and energy‐dispersive X‐ray analysis indicate that the products are pure Cu and of cubic phase. The morphology of the products can be controlled between nanotubes and microspheres assembled from hollow nanoparticles by adjusting the concentration of sodium dodecyl sulfate. A series of experiments confirm that the concentration of the glucose and NaOH also play important roles in the formation of the hollow Cu nano/microstructures.     

SLIDING MODE PREDICTION TRACKING CONTROL DESIGN FOR UNCERTAIN SYSTEMS

In this paper, a tracking control algorithm based on sliding mode prediction for a class of discrete‐time uncertain systems is presented. By creating a special model to predict the future sliding mode function value and by combining feedback correction and receding horizon optimization approaches, which are extensively applied in predictive control strategy, a discrete‐time sliding mode control law for tracking problem is constructed. With the designed control law, closed‐loop systems have strong robustness to matched or unmatched uncertainties as they eliminate chattering. Besides, in the robustness analysis, the boundary condition for uncertainties, which is a universal presupposition in sliding mode control method, is not required. Numerical simulation and cart‐pendulum experiment results illustrate the validity of the proposed algorithm.     

基站电磁环境测试方法的比较与分析

GSM移动通信基站电磁辐射测量常用的方法有两种,一种是用频谱分析仪和定向天线进行测量,计算出辐射功率密度;另一种是用射频电磁辐射仪,可以直接读出辐射功率密度.对实际运行的基站,两种方法的测量结果不一致,通过在实验室的反复实验,分析出这两种测量方法的特点,找到了测量结果不一致的原因.电磁辐射的测量不仅要了解测量方法的特点,还要了解辐射信号的特性,才能给出恰当的测试结论.     

DNA double-strand break repair: a theoretical framework and its application

DNA double-strand breaks (DSBs) are formed as a result of genotoxic insults, such as exogenous ionizing radiation, and are among the most serious types of DNA damage. One of the earliest molecular responses following DSB formation is the phosphorylation of the histone H2AX, giving rise to γH2AX. Many copies of γH2AX are generated at DSBs and can be detected in vitro as foci using well-established immuno-histochemical methods. It has previously been shown that anti-γH2AX antibodies, modified by the addition of the cell-penetrating peptide TAT and a fluorescent or radionuclide label, can be used to visualize and quantify DSBs in vivo. Moreover, when labelled with a high amount of the short-range, Auger electron-emitting radioisotope, ¹¹¹In, the amount of DNA damage within a cell can be increased, leading to cell death. In this report, we develop a mathematical model that describes how molecular processes at individual sites of DNA damage give rise to quantifiable foci. Equations that describe stochastic mean behaviours at individual DSB sites are derived and parametrized using population-scale, time-series measurements from two different cancer cell lines. The model is used to examine two case studies in which the introduction of an antibody (anti-γH2AX-TAT) that targets a key component in the DSB repair pathway influences system behaviour. We investigate: (i) how the interaction between anti-γH2AX-TAT and γH2AX effects the kinetics of H2AX phosphorylation and DSB repair and (ii) model behaviour when the anti-γH2AX antibody is labelled with Auger electron-emitting ¹¹¹In and can thus instigate additional DNA damage. This work supports the conclusion that DSB kinetics are largely unaffected by the introduction of the anti-γH2AX antibody, a result that has been validated experimentally, and hence the hypothesis that the use of anti-γH2AX antibody to quantify DSBs does not violate the image tracer principle. Moreover, it provides a novel model of DNA damage accumulation in the presence of Auger electron-emitting ¹¹¹In that is supported qualitatively by the available experimental data.     

Harnessing information for development: A proposal for a world bank group vision and strategy∗

Abstract

Revolutionary advances in information technology reinforce economic and social changes that are transforming business and society. A new kind of economy ‐ the information economy ‐ is emerging where trade and investment are global and firms compete with knowledge, networking and agility on a global basis. A corresponding new society is also emerging with pervasive information capabilities that make it substantially different from an industrial society: more competitive, more democratic, less centralized, less stable, better able to address individual needs, and friendlier to the environment.

These changes dictate, for all countries, a major adjustment to harness information for economic and social development. This adjustment requires urgent new policies, regulatory and institutional reforms, and investments. Through this adjustment, countries must achieve macroeconomic balance, political stability, and growth amidst global information flows, competition, trade, and investment. Advanced countries are rapidly adjusting. Developing countries must also adjust or risk exclusion from the global economy and severe competitive disadvantage for their goods and services.

Fortunately, the information revolution creates both the challenge and the means for countries to adjust to new ways of doing business and to put in place the needed infrastructure of telecommunications and information systems. The information revolution also creates extraordinary new opportunities to attack vexing problems of poverty, inequality, and environmental degradation.

To harness information and information technology for its mission of poverty alleviation and sustainable economic development, the World Bank Group will pursue four objectives in its assistance strategy:

• Widespread and equitable access to communication and information services through accelerated deployment of national information infrastructure and effective integration into international communication and information networks.

• Systemic improvements in the functioning and competitiveness of key economic sectors through strategic information policies and systems.

• New ways to use information technology to help solve the most pressing problems of human and economic development ‐ education, health, poverty alleviation, rural development, and care for the environment.

• Increased impact of the entire range of World Bank Group operations through inclusion of effective information components.

The World Bank Group will be a long‐term partner and facilitator for countries adjusting to the information economy. It will cooperate with them on information policy, strategy, and project design at the national and sectoral levels. To this end, it will develop strategic alliances to mobilize worldwide knowledge and financing, including its own. In addition, the World Bank Group will increase the level and effectiveness of the information content of its projects in all sectors and will explore new frontiers of development through information‐intensive projects.     

Building facade detection,segmentation, and parameter estimation for mobile robot stereo vision

Building facade detection is an important problem in computer vision, with applications in mobile robotics and semantic scene understanding. In particular, mobile platform localization and guidance in urban environments can be enabled with accurate models of the various building facades in a scene. Toward that end, we present a system for detection, segmentation, and parameter estimation of building facades in stereo imagery. The proposed method incorporates multilevel appearance and disparity features in a binary discriminative model, and generates a set of candidate planes by sampling and clustering points from the image with Random Sample Consensus (RANSAC), using local normal estimates derived from Principal Component Analysis (PCA) to inform the planar models. These two models are incorporated into a two-layer Markov Random Field (MRF): an appearance- and disparity-based discriminative classifier at the mid-level, and a geometric model to segment the building pixels into facades at the high-level. By using object-specific stereo features, our discriminative classifier is able to achieve substantially higher accuracy than standard boosting or modeling with only appearance-based features. Furthermore, the results of our MRF classification indicate a strong improvement in accuracy for the binary building detection problem and the labeled planar surface models provide a good approximation to the ground truth planes.