全文获取类型
收费全文 | 7614篇 |
免费 | 414篇 |
国内免费 | 249篇 |
专业分类
电工技术 | 326篇 |
综合类 | 351篇 |
化学工业 | 1094篇 |
金属工艺 | 377篇 |
机械仪表 | 299篇 |
建筑科学 | 468篇 |
矿业工程 | 125篇 |
能源动力 | 221篇 |
轻工业 | 391篇 |
水利工程 | 84篇 |
石油天然气 | 255篇 |
武器工业 | 37篇 |
无线电 | 668篇 |
一般工业技术 | 912篇 |
冶金工业 | 1841篇 |
原子能技术 | 76篇 |
自动化技术 | 752篇 |
出版年
2024年 | 21篇 |
2023年 | 88篇 |
2022年 | 140篇 |
2021年 | 223篇 |
2020年 | 183篇 |
2019年 | 170篇 |
2018年 | 144篇 |
2017年 | 171篇 |
2016年 | 168篇 |
2015年 | 169篇 |
2014年 | 252篇 |
2013年 | 350篇 |
2012年 | 314篇 |
2011年 | 396篇 |
2010年 | 320篇 |
2009年 | 306篇 |
2008年 | 338篇 |
2007年 | 313篇 |
2006年 | 343篇 |
2005年 | 311篇 |
2004年 | 209篇 |
2003年 | 214篇 |
2002年 | 169篇 |
2001年 | 167篇 |
2000年 | 138篇 |
1999年 | 220篇 |
1998年 | 555篇 |
1997年 | 379篇 |
1996年 | 290篇 |
1995年 | 197篇 |
1994年 | 171篇 |
1993年 | 157篇 |
1992年 | 62篇 |
1991年 | 86篇 |
1990年 | 63篇 |
1989年 | 61篇 |
1988年 | 62篇 |
1987年 | 54篇 |
1986年 | 37篇 |
1985年 | 25篇 |
1984年 | 6篇 |
1983年 | 11篇 |
1982年 | 14篇 |
1981年 | 14篇 |
1980年 | 17篇 |
1979年 | 6篇 |
1978年 | 8篇 |
1977年 | 42篇 |
1976年 | 97篇 |
1975年 | 11篇 |
排序方式: 共有8277条查询结果,搜索用时 15 毫秒
11.
The evaporation kinetics of Zn and Pb from liquid iron at 1600°C were studied under argon pressure 0.1 to 50 bar in an induction furnace. It was found that the limiting step of evaporation under pAr < 1 bar is diffusion in the melt. Diffusion in the gas phase becomes rate-determining with increasing argon pressure. The phase boundary reaction has no effect on the evaporation of Zn and Pb. The evaporation of Zn can evidently be reduced by increasing argon pressure above 1 bar, while the evaporation of Pb is not significantly effected by changes of argon pressure. 相似文献
12.
To determine the most effective treatment for acrodermatitis chronica atrophicans, several clinical trials were undertaken in recent years to evaluate whether a 2-week course of ceftriaxone would be superior to oral antibiotics. Of the 46 patients suffering from acrodermatitis chronica atrophicans, 14 were treated with ceftriaxone 2g for 15 days. The remaining patients received either oral penicillin V 1.5 million IU t.i.d. or doxycycline 100 mg b.i.d. for 20 to 30 days. Patients were followed up for at least 1 year. Of the 14 ceftriaxone-treated patients four showed incomplete regression of the inflammatory skin changes after 6 to 12 months. Two out of five patients who were monitored for Borrelia burgdorferi DNA excretion were still positive after 12 months as compared to none of six patients who were treated orally for 20-30 days. Six out of 11 patients treated orally for only 20 days needed retreatment after 6 months because of continuing skin manifestations, neuropathy or arthralgia. A 30-day duration of treatment with oral antibiotics and not the chosen antibiotic is crucial for curing acrodermatitis chronica atrophicans. The duration of treatment with ceftriaxone needed for eradication of Borrelia in acrodermatitis chronica atrophicans has yet to be determined in future studies. 相似文献
13.
14.
15.
16.
Phospholipid transfer protein (PLTP) was purified from lipoprotein-free human plasma, obtained upon treatment of plasma with dextran sulfate and Ca2+, by employing a series of column chromatography. Upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the purified PLTP showed a single main band, corresponding to the molecular mass of 78 kDa. However, isoelectric focusing of the purified preparation gave multiple bands with pI ranging from 4.3 to 5.1, indicative of microheterogeneity. Purified PLTP was shown to possess not only phospholipid transfer activity, but also high density lipoprotein (HDL) conversion activity (Tu, A.-Y., Nishida, H. I., and Nishida, T. (1990), FASEB J. 4, A2148; Jauhiainen, M., Metso, J., Pahlman, R., Blomqvist, S., van Tol, A., and Ehnholm, C. (1993) J. Biol. Chem. 268, 4032-4036). Isolated HDL3 was enlarged to the size of HDL2b upon incubation with purified PLTP for 6 h at 37 degrees C at the PLTP/HDL3 molar ratio of approximately 1:45. Both the HDL conversion and the phosphatidylcholine transfer activities of purified PLTP were effectively inhibited by rabbit anti-PLTP immunoglobulin G. The primary importance of PLTP in the HDL enlargement that occurs in human plasma upon incubation at 37 degrees C was shown by the strong inhibitory effect of the anti-PLTP immunoglobulin G. The process of PLTP-mediated HDL enlargement was accompanied by the release of apoproteins, primarily apoA-I. HDL3 enlargement mediated by PLTP was effectively inhibited by the addition of free fatty acids. 相似文献
17.
S Whitman L Lacey D Ansell EH Chen J Dell CW Phillips 《Canadian Metallurgical Quarterly》1993,22(3):393-397
Magnetic resonance imaging allows a noninvasive assessment of myelination during normal brain maturation as well as the detection of genetically determined and acquired diseases that affect the synthesis and maintenance of myelin. If this high sensitivity of magnetic resonance imaging for white matter changes is completed by adequate clinical and biochemical information, a unique diagnostic tool is available to gain new insights in the formation of myelin and pathogenesis of myelin disorders. 相似文献
18.
Membrane segment 5 (M5) is thought to play a direct role in cation transport by the sarcoplasmic reticulum Ca2+-ATPase and the Na+, K+-ATPase of animal cells. In this study, we have examined M5 of the yeast plasma membrane H+-ATPase by alanine-scanning mutagenesis. Mutant enzymes were expressed behind an inducible heat-shock promoter in yeast secretory vesicles as described previously (Nakamoto, R. K., Rao, R., and Slayman, C. W. (1991) J. Biol. Chem. 266, 7940-7949). Three substitutions (R695A, H701A, and L706A) led to misfolding of the H+-ATPase as evidenced by extreme sensitivity to trypsin; the altered proteins were arrested in biogenesis, and the mutations behaved genetically as dominant lethals. The remaining mutants reached the secretory vesicles in sufficient amounts to be characterized in detail. One of them (Y691A) had no detectable ATPase activity and appeared, based on trypsinolysis in the presence and absence of ligands, to be blocked in the E1-to-E2 step of the reaction cycle. Alanine substitution at an adjacent position (V692A) had substantial ATPase activity (54%), but was likewise affected in the E1-to-E2 step, as evidenced by shifts in its apparent affinity for ATP, H+, and orthovanadate. Among the mutants that were sufficiently active to be assayed for ATP-dependent H+ transport by acridine orange fluorescence quenching, none showed an appreciable defect in the coupling of transport to ATP hydrolysis. The only residue for which the data pointed to a possible role in cation liganding was Ser-699, where removal of the hydroxyl group (S699A and S699C) led to a modest acid shift in the pH dependence of the ATPase. This change was substantially smaller than the 13-30-fold decrease in K+ affinity seen in corresponding mutants of the Na+, K+-ATPase (Arguello, J. M., and Lingrel, J. B (1995) J. Biol. Chem. 270, 22764-22771). Taken together, the results do not give firm evidence for a transport site in M5 of the yeast H+-ATPase, but indicate a critical role for this membrane segment in protein folding and in the conformational changes that accompany the reaction cycle. It is therefore worth noting that the mutationally sensitive residues lie along one face of a putative alpha-helix. 相似文献
19.
20.