The unsteady-state thermohydraulic calculation of a stacked core

NIKIÉT. Translated from Atomnaya Énergiya, Vol. 75, No. 4, pp. 265-269, October, 1993.     

On obtaining shape from color shading

Color and Grassmann-Cayley Coordinates of Shape are considered in this article. The image irradiance equation for colored surfaces and the Grassman manifold λ of orbits Q = {B · h + c; detB ≠ 0} Where c is a vector sweeping the color space H, B is a 3 × 3 matrix, and h(x, y) is the color image of a Lambertian surface assumed to be a linear vector-function of the normal vectors. Different orbits Q(n) correspond to different shapes but they are invariant under color and illuminant transformation. Coordinates of an orbit Q in λ can be computed as 3 × 3 (2 × 2, sometimes) determining the elements of which are values of some linear functionals (receptive fields) of h(x, y). Based on the approach, a shape-from-shading algorithm was developed and successfully tested on the threeband color images of various real objects (an egg, cylinders and cones made of paper, etc.). © 1993 John Wiley & Sons, Inc.     

DSS research and practice in perspective

The aim of this paper is to assess the state-of-the-art in the Decision Support Systems (DSS) field from both a research and a practice perspective. Three main dimensions of DSS research and practice are addressed: 1) supporting human decision-making processes, 2) integrating DSS into the organizational context, and 3) identifying new application domains. The related analysis and discussion provides a better understanding of past developments in the DSS field and insights into future evolution patterns.     

The solubility of tungsten in molten iron

The solubility of tungsten in iron has been determined at 1560–1620°C by successively saturating molten iron with tungsten while ensuring a uniform distribution of the content over the height. The temperature dependence of the solubility over that temperature range is described by a Schröder equation: C_s=(3.94±0.11)×10³e-(84.4±0.4)/RT.     

Wideband chirp measurement technique for high bit rate sources

A Mach Zehnder (MZ) interferometer has been used as an optical discriminator to measure the time-resolved frequency chirp of an optical source     

Continuously distributed phase shifts in chirped DFB lasers usingbent waveguides

The authors have implemented chirped distributed feedback (DFB) grating lasers with phase shifts [λ/8, 2λ/8 and 3λ/8] distributed continuously over various axial distances, using their recently proposed method for producing bent optical waveguides. The singlemode stability of the lasers with distributed phase shifts was found to be considerably higher than for lasers with abrupt phase shifts     

HLA-DR mismatching correlates with early cardiac allograft rejection, incidence, and graft survival when high-confidence-level serological DR typing is used

To determine if cardiac allograft outcome is improved among patients with fewer HLA-DR mismatches with their donors, we studied 132 recipients of a primary cardiac allograft who were transplanted between December 1985 and December 1991. These recipients and their donors all had high-confidence-level serological HLA-DR typing, previously shown to correlate highly with DNA DR typing. Patients were divided in two groups based on the HLA-DR mismatch with their donors. Group I consisted of 78 patients with 1 or zero DR mismatch and group II of 54 patients with 2 DR mismatches. Allograft outcome measurements included incidence of moderate rejection, incidence of allograft vasculopathy at 12 months, cardiac function measured as left ventricular ejection fraction (LVEF) and cardiac index (CI), and actuarial graft survival up to 7 years. Groups I and group II were not different with regard to recipient age, donor age, ischemia time, pulmonary vascular resistance, sex, or PRA greater than 0%. Group II had a higher incidence of moderate rejection on the first-week biopsy (47% vs. 25%, P = 0.019), and during the first month (84% vs. 58%, P = 0.006), but no difference was found in frequency of rejection from months 2 to 12. LVEF was not different in the groups at any point. CI was better in group I at 12 months (2.76 vs. 2.5, P = 0.03). No statistically significant difference was found in incidence of allograft vasculopathy (17% vs. 26%, P = 0.204). Actual graft survival at 1 year was better for group I (91% vs. 74%, P = 0.008), and actuarial graft survival at 6 years also favored group I (76% vs. 56%, P = 0.04). Using high-confidence-level serological HLA-DR typing assignments we demonstrated that HLA-DR mismatching correlates highly with cardiac allograft outcome. Implications are that heart transplant survival could be improved if prospective matching were feasible and prioritized or if immunosuppression were tailored to the HLA-DR match.     

Pathology of Toxoplasma gondii infection in the nude rat. An experimental model of toxoplasmosis in the immunocompromised host?

Genetically athymic nu/nu (nude) rats, deficient in T cells, die from infection with various Toxoplasma gondii strains, including RH and Prugniaud strains. In contrast, these strains cause chronic infections without apparent symptoms in immunocompetent non-nude rats. We show here that nude rats die in two to three weeks after RH infection and three to four weeks after Prugniaud infection. Histological examination of brains from nude rats at different time points after infection, revealed an absence of lesions after RH strain infection and cysts with usually no inflammation after Prugniaud infection. Lungs from nude rats developed a fibrin alveolitis using either strain, whereas myocarditis with focal areas of necrosis were observed only after Prugniaud infection. Cysts and, in some cases, tachyzoites in the necrotic lesions were easily identifiable. The two strains of T. gondii elicited in nude rats a granulomatous hepatitis that only differed in intensity. Spleen and mesenteric lymph nodes appeared totally non reactive in both cases. This model allows immunological and parasitological studies by comparison with immunocompetent rat infection. Published data concerning toxoplasma pathology in AIDS, therefore, suggest that acute toxoplasma infection in nude rats may be a useful model for studying disseminated forms of toxoplasma infection found in AIDS patients.     

Lipopolysaccharide primes human alveolar macrophages for enhanced release of superoxide anion and leukotriene B4: self-limitations of the priming response with protein synthesis

Human alveolar macrophages (AM) can produce potent reactive oxygen intermediates (ROI) and arachidonic acid metabolites (eicosanoids), which have important roles in host defense and the pathogenesis of some diseases of the lung. Bacterial lipopolysaccharide (LPS) is believed to cause profound lung injury and can prime mouse peritoneal macrophages for the enhanced secretion of ROI and eicosanoids. Therefore, we investigated the effect of LPS pretreatment on the ability of AM to release superoxide anions (O2-) and leukotriene B4 (LTB4). LPS can prime AM for the enhanced secretion of O2- and LTB4, regardless of whether they are derived from nonsmokers or smokers. Moreover, judging from the time-response characteristics, this priming for LTB4 release could be inhibited in the later stages of pretreatment, when the O2(-)-releasing capacity was enhanced. The priming inhibition was prevented, at least in part, by cycloheximide, but not by SOD and/or catalase. In addition, cycloheximide also inhibited the priming for O2- release. Hence, protein synthesis might be necessary for the priming for O2- release and for inhibiting the priming for LTB4 release. This phenomenon of self-limiting the priming response with LPS seems to be very important when we consider the high oxygen tension in the lungs and the many bacterial substances inspired into alveoli.