Predictive Thermal Inactivation Model for Effects and Interactions of Temperature, NaCl, Sodium Pyrophosphate, and Sodium Lactate on Listeria monocytogenes in Ground Beef

The effects and interactions of heating temperature (60 °C to 73.9 °C), salt (0.0 % to 4.5 %?w/v), sodium pyrophosphate (0.0 % to 0.5 %?w/v), and sodium lactate (0.0 % to 4.5 %?w/v) on the heat resistance of a five-strain mixture of Listeria monocytogenes in 75 % lean ground beef were examined. Meat samples in sterile filtered stomacher bags were heated in a temperature controlled waterbath to determine thermal death times. The recovery medium was tryptic soy agar supplemented with 0.6 % yeast extract and 1 % sodium pyruvate. Weibull survival functions were employed to model the primary survival curves. Then, survival curve-specific estimated parameter values obtained from the Weibull model were used for determining a secondary model. The results indicate that temperature and salt have a large impact on the inactivation kinetics of L. monocytogenes, while sodium lactate (NaL) has an impact in the presence of salt. The model presented in this paper for predicting inactivation of L. monocytogenes can be used as an aid in designing lethality treatments meant to control the presence of this pathogen in ready-to-eat products.     

Influence of Grain Boundary Complexion on Deformation Mechanism of High Temperature Bending Creep Process of Cu Bicrystal

Despite of substantial advancement, the effect of grain boundary (GB) complexions on high temperature creep deformation process has not been fully understood. In this paper, we have studied the high temperature bending creep deformation of copper bicrystal with various GB complexions under different loads using molecular dynamics simulation. It has been found that specimen with normal kite GB complexion have better creep resistance properties when subjected to comparatively lower applied load. In case of monolayer Zr segregation, a drastic decrease in creep strength as well as creep plasticity is observed due to inhibition of GB migration. On the other hand, deviation between creep properties for specimen with split-kite GB complexion and split-kite bilayer Zr segregation GB complexion is minimal. Enhanced creep plasticity is observed in case of split-kite bilayer Zr segregation GB complexion, which is due to formation of interpenetrating icosahedral clusters in the necking region. Fracture in specimen with monolayer Zr segregation GB complexion has occurred by means of slip phenomenon at lower deformation load whereas amorphization and necking is observed at higher deformation load. In case of specimen with bilayer Zr segregation GB complexion, it is found that fracture has occurred through amorphization and necking at all deformation loads due to higher GB thickness.     

Reflection and Transmission of Plane Waves at the Planar Interface of a General Uniaxial Medium and Free Space

Abstract

A general uniaxial medium is characterized by its permittivity and permeability tensors having the same preferred axis. The plane wave reflection and transmission characteristics of a planar interface between free space and a general uniaxial medium have been obtained; since application as a polarizer is envisioned, the preferred axis lies in a plane parallel to the interface. Application of the Brewster law, as well as conditions for total reflection are explored.     

Transported snapshot model order reduction approach for parametric,steady-state fluid flows containing parameter-dependent shocks

A new model order reduction approach is proposed for parametric steady-state nonlinear fluid flows characterized by shocks and discontinuities whose spatial locations and orientations are strongly parameter dependent. In this method, solutions in the predictive regime are approximated using a linear superposition of parameter-dependent basis. The sought-after parametric reduced bases are obtained by transporting the snapshots in a spatially and parametrically dependent transport field. Key to the proposed approach is the observation that the transport fields are typically smooth and continuous, despite the solution themselves not being so. As a result, the transport fields can be accurately expressed using a low-order polynomial expansion. Similar to traditional projection-based model order reduction approaches, the proposed method is formulated mathematically as a residual minimization problem for the generalized coordinates. The proposed approach is also integrated with well-known hyper-reduction strategies to obtain significant computational speedups. The method is successfully applied to the reduction of a parametric one-dimensional flow in a converging-diverging nozzle, a parametric two-dimensional supersonic flow over a forward-facing step, and a parametric two-dimensional jet diffusion flame in a combustor.     

Rolling element bearing design through genetic algorithms

The design of rolling element bearings has been a challenging task in the field of mechanical engineering. While most of the real aspects of the design are never disclosed by bearing manufacturers, the common engineer is left with no other alternative than to refer to standard tables and charts containing the bearing performance characteristics. This paper presents a more viable method to solve this problem using genetic algorithms (GAs). Since the algorithm is basically a guided random search, it weakens the chances of getting trapped in local maxima or minima. The method used has yielded improved performance parameters than those catalogued in standard tables.     

Ternary Solvent System to Control the Morphology of Active Blend in Inverted Organic Solar Cells

Bulk heterojunction blend of poly(3-hexylthiophene)–[6,6]-phenyl-C₆₁-butyric acid methyl ester prepared using the ternary solvent mixture was used as the active layer of an inverted organic solar cell. The ternary solvent mixture consisted of a good solvent such as ortho-dichlorobenzene and two marginal solvents such as cyclohexanone and toluene offering limited solubility to the poly(3-hexylthiophene) component. Power conversion efficiency of inverted device was found to decrease from 2.74?±?0.05% in the unmodified device to 2.64?±?0.07% in the modified device. UV–visible measurement revealed less efficient photoabsorption in the mixed cosolvent-casted active layer due to insufficient and disordered crystallization of poly(3-hexylthiophene) domains.     

γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status

The hazard of ionizing radiation exposure due to nuclear accidents or terrorist attacks is ever increasing. Despite decades of research, still, there is a shortage of non-toxic, safe and effective medical countermeasures for radiological and nuclear emergency. To date, the U.S. Food and Drug Administration (U.S. FDA) has approved only two growth factors, Neupogen (granulocyte colony-stimulating factor (G-CSF), filgrastim) and Neulasta (PEGylated G-CSF, pegfilgrastim) for the treatment of hematopoietic acute radiation syndrome (H-ARS) following the Animal Efficacy Rule. Promising radioprotective efficacy results of γ-tocotrienol (GT3; a member of the vitamin E family) in the mouse model encouraged its further evaluation in the nonhuman primate (NHP) model. These studies demonstrated that GT3 significantly aided the recovery of radiation-induced neutropenia and thrombocytopenia compared to the vehicle controls; these results particularly significant after exposure to 5.8 or 6.5 Gray (Gy) whole body γ-irradiation. The stimulatory effect of GT3 on neutrophils and thrombocytes (platelets) was directly and positively correlated with dose; a 75 mg/kg dose was more effective compared to 37.5 mg/kg. GT3 was also effective against 6.5 Gy whole body γ-irradiation for improving neutrophils and thrombocytes. Moreover, a single administration of GT3 without any supportive care was equivalent, in terms of improving hematopoietic recovery, to multiple doses of Neupogen and two doses of Neulasta with full supportive care (including blood products) in the NHP model. GT3 may serve as an ultimate radioprotector for use in humans, particularly for military personnel and first responders. In brief, GT3 is a promising radiation countermeasure that ought to be further developed for U.S. FDA approval for the ARS indication.     

Mutual authentication framework using fog computing in healthcare

Multimedia Tools and Applications - The development of the medical services framework is advanced by the development of the Internet of Things (IoT) innovation. There are many hindrances in the...     

Attention-based multimodal contextual fusion for sentiment and emotion classification using bidirectional LSTM

Multimedia Tools and Applications - Due to the availability of an enormous amount of multimodal content on the social web and its applications, automatic sentiment analysis, and emotion detection...