Context-Processing Deficits in Schizotypal Personality Disorder.

Research suggests that schizotypal personality disorder (SPD) is a part of the spectrum of schizophrenia-related illnesses. This article hypothesizes that a deficit in the representation and maintenance of context is a core cognitive disturbance in schizophrenia and that SPD individuals should demonstrate context-processing deficits. To test this hypothesis, the authors administered 3 versions of their AX-CPT task, designed to assess context processing, to 35 healthy controls and 26 individuals with DSM-IV SPD. They also administered working memory and selective attention tasks. SPD individuals displayed context representation deficits similar to those found in schizophrenia but did not show the same additional deficits in context maintenance. Context processing was strongly associated with working memory and selective attention performance in the SPD individuals. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Three-dimensional self-assembly of spherical block copolymer domains into V-shaped grooves

The self-assembly of a spherical-morphology block copolymer into V-shaped grooves has been investigated. Although spherical morphology block copolymers typically form a bcc sphere array in bulk, the V groove promotes the formation of a well-ordered fcc close-packed sphere array with the (111) planes of the array parallel to the groove walls. The sphere size in the block copolymer adjusts depending on the commensurability between the periodicity of the block copolymer and the film thickness within the V groove. The top surface of the close-packed array, parallel to the substrate, shows a square symmetry, unlike the hexagonal symmetry seen in monolayers of spherical domains, which may provide a useful geometry for block copolymer lithography.     

Ageing in the LHCb outer tracker: Aromatic hydrocarbons and wire cleaning

The LHCb Outer Tracker straw tubes have shown to suffer from gain loss after irradiation in the laboratory at moderate intensities. Under irradiation an insulating layer is formed on the anode wire. The ageing is caused by contamination of the counting gas due to outgassing of the plastifier di-isopropyl-naphthalene in araldite AY103-1 used at construction. This paper presents irradiation results with and without the plastifier, together with the mass spectra of the glue samples. In addition, the effects of wire heating and large currents are presented.     

Nanomaterials for X-ray imaging: gold nanoparticle enhancement of X-ray scatter imaging of hepatocellular carcinoma

We present the development of a new imaging technique for the early diagnosis of hepatocellular carcinoma that utilizes surface-modified gold nanoparticles in combination with X-ray imaging. Tissues labeled with these electron-dense particles show enhanced X-ray scattering over normal tissues, distinguishing cells containing gold nanoparticles from cells without gold in X-ray scatter images. Our results suggest that this novel approach could enable the in vivo detection of tumors as small as a few millimeters in size.     

Psychological resilience and dysfunction among hospitalized survivors of the SARS epidemic in Hong Kong: A latent class approach.

Objective: To examine trajectories of psychological functioning using latent class analysis on a sample of hospitalized survivors of the 2003 severe acute respiratory syndrome (SARS) epidemic in Hong Kong. Design: A longitudinal study of 997 survivors, recruited from among 1,331 individuals hospitalized for SARS, were interviewed at 6, 12, and 18 months after hospitalization. Main Outcome Measures: Psychological and physical functioning at each time point was measured using the 12-item Medical Outcome Study Short-Form Health Survey (SF-12). Results: Four latent classes were identified-chronic dysfunction, delayed dysfunction, recovery, and resilience. All groups had better physical health than the chronic group. Resilient and recovered individuals had greater social support and less SARS-related worry, and resilient individuals were more likely to be male. The resilient group also had greater social support than the delayed group and better physical functioning than the recovered group. Conclusion: This study demonstrated that longitudinal outcome trajectories following a major health-threat event in an Asian sample bear close resemblance to prototypical trajectories observed in trauma studies using Western samples. Unique predictors of the trajectories included factors observed in previous studies, such as social support, as well as factors of particular relevance to a major disease outbreak, such as SARS-related worry. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

In the Eye of the Storm: Race and Genomics in Research and Practice.

The difficulties of operationalizing race in research and practice for social, behavioral, and genetic researchers and practitioners are neither new nor related to recent genetic knowledge. For geneticists, the bases for understanding groups are clines, observed traits that gradually change in frequency between geographic regions without distinct identifiable population boundaries and population histories that carry information about the distribution of genetic variants. For psychologists, race may not exist or be a social and cultural construct associated with fluid social inferences. Because definitions of populations and race can be socially and biologically incongruent, the authors suggest that geneticists and social and behavioral scientists and clinicians attend to external validity issues by operationalizing population and racial categories and avoiding race proxies for other biological, social, and cultural constructs in research designs, data analyses, and clinical practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Diversity training in graduate school: An exploratory evaluation of the Safe Zone project.

How can psychologists and graduate students become more affirmative of lesbian, gay, bisexual, and transgender (LGBT) issues? Safe Zone is a diversity-training program to increase sensitivity toward, knowledge of, and advocacy for LGBT populations and issues that affect them. In this exploratory study, the implementation of Safe Zone is described within a school of professional psychology; its effectiveness was assessed by self-reported behavioral and attitudinal changes and from participant evaluations. Results were encouraging with regard to the goals of Safe Zone and its adaptation to institutions interested in improving relations with the LGBT community, but additional empirical studies are needed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Therapeutic Reactance as a Predictor of Outcome in the Treatment of Chronic Depression.

This study examined whether reactance would negatively influence treatment outcome in 347 patients diagnosed with chronic forms of depression and treated at 9 sites with either Nefazodone, cognitive-behavioral analysis system of psychotherapy (CBASP), or combination therapy. Contrary to our hypotheses, reactance positively predicted treatment outcome in CBASP on 2 of 4 scales. These effects were independent of the therapeutic alliance, which also positively predicted outcome. Reactance did not predict outcome in the groups receiving medication alone or in combination with CBASP. The findings suggest that reactance may be an asset in psychotherapy among chronically depressed individuals and that reactant patients can benefit from directive psychotherapy when therapists flexibly respond to perturbations in the therapeutic relationship. Results support the importance of Aptitude × Treatment interactions in psychotherapy outcome. The direction and significance of such interactions may vary with different forms of psychopathology. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Role of impulsivity in the relationship between depression and alcohol problems among emerging adult college drinkers.

Depression is common among college students and higher levels of depression are associated with greater alcohol-related problems. However, depression is frequently not found to be directly associated with more alcohol use. This study examined whether various aspects of impulsivity (negative urgency, lack of premeditation, lack of perseverance, sensation seeking, and delay discounting) and drinking to cope with negative affect help to account for the relationship between depression and alcohol problems among emerging adult college drinkers who reported at least a minimal level of depressive symptoms. In this cross-sectional study, 143 emerging adult (between 18 and 25 years old) female (69.9%, n = 100) and male (30.1%, n = 43) college drinkers with at least minimal depressive symptoms completed measures of depression, alcohol use and problems, drinking to cope, and impulsivity. A multiple mediation analysis revealed that only negative urgency and drinking to cope partially mediated the depression-alcohol problems relationship. Moderated mediation analyses revealed that impulsivity-related constructs did not significantly interact with drinking to cope to increase alcohol problems. It appears that alcohol use is particularly problematic for students with elevated depression, and this is partly attributable to depression's association with negative urgency, in addition to its association with drinking to cope. Our findings suggest that students who suffer from depression may engage in problematic drinking behavior in part because negative affect is detrimental to their short-term impulse control and decision making, independent of maladaptive attempts to regulate affect through drinking to cope. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Canadian counselling psychology: From defining moments to ways forward.

Counselling psychology in Canada is a distinct and vibrant professional area representing the contributions of many people and events within a unique context. This article elaborates a number of defining moments or actions that reveal the distinct nature of this professional area through a recursive and interactive process with the social context. A number of ways forward are proposed as specific professional developments, as well as the resolution of a number of substantive issues identified within the recently adopted definition of counselling psychology. Moving forward as a discipline and a practice will actualize the potential of counselling psychology as both world and life enhancing. (PsycINFO Database Record (c) 2011 APA, all rights reserved)