Blue-Green (~480 nm) versus Blue (~460 nm) Light for Newborn Phototherapy—Safety Considerations

We have previously shown that the phototherapy of hyperbilirubinemic neonates using blue-green LED light with a peak wavelength of ~478 nm is 31% more efficient for removing unconjugated bilirubin from circulation than blue LED light with a peak wavelength of ~452 nm. Based on these results, we recommended that the phototherapy of hyperbilirubinemic newborns be practiced with light of ~480 nm. Aim: Identify and discuss the most prominent potential changes that have been observed in the health effects of phototherapy using either blue fluorescent- or blue LED light and speculate on the expected effects of changing to blue-green LED light phototherapy. Search the phototherapy literature using the terms neonate, hyperbilirubinemia, and phototherapy in the PubMed and Embase databases. Transitioning from blue fluorescent light to blue-green LED light will expose neonates to less light in the 400–450 nm spectral range, potentially leading to less photo-oxidation and geno-/cytotoxicity, reduced risk of cancer, and decreased mortality in extremely low-birthweight neonates. The riboflavin level may decline, and the increased production and retention of bronze pigments may occur in predisposed neonates due to enhanced lumirubin formation. The production of pre-inflammatory cytokines may rise. Hemodynamic responses and transepidermal water loss are less likely to occur. The risk of hyperthermia may decrease with the use of blue-green LED light and the risk of hypothermia may increase. Parent–neonate attachment and breastfeeding will be positively affected because of the shortened duration of phototherapy. The latter may also lead to a significant reduction in the cost of phototherapy procedures as well as the hospitalization process.     

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A Provable Secure ID-Based Explicit Authenticated Key Agreement Protocol Without Random Oracles

In this paper, we present an identity-based explicit authenticated key agreement protocol that is provably secure without random oracles. The protocol employs a new method to isolate a session key from key confirmation keys so that there is no direct usage of hash functions in the protocol. The protocol is proved secure without random oracles in a variant of Bellare and Rogaway style model, an exception to current proof method in this style model in the ID-based setting. We believe that this key isolation method is novel and can be further studied for constructing more effcient protocols.     

A classification of predictive-reactive project scheduling procedures

The vast majority of the project scheduling research efforts over the past several years have concentrated on the development of workable predictive baseline schedules, assuming complete information and a static and deterministic environment. During execution, however, a project may be subject to numerous schedule disruptions. Proactive-reactive project scheduling procedures try to cope with these disruptions through the combination of a proactive scheduling procedure for generating predictive baseline schedules that are hopefully robust in that they incorporate safety time to absorb anticipated disruptions with a reactive procedure that is invoked when a schedule breakage occurs during project execution. In this paper we discuss the results obtained by a large experimental design set up to evaluate several predictive-reactive resource-constrained project scheduling procedures under the composite objective of maximizing both the schedule stability and the timely project completion probability.     

How to construct identity-based signatures without the key escrow problem

The inherent key escrow problem is one of the main reasons for the slow adoption of identity-based cryptography. The existing solution for mitigating the key escrow problem is by adopting multiple Private Key Generators (PKGs). Recently, there was a proposal that attempted to reduce the trust of the PKG by allowing a malicious PKG to be caught if he reveals the user’s identity-based private key illegally. Nonetheless, the proposal does not consider that the PKG can simply decrypt the ciphertext instead of revealing the private key itself (in the case of identity-based encryption schemes). The aim of this paper is to present an escrow-free identity-based signature (IBS) scheme, in which the malicious PKG will be caught if it releases a signature on behalf of the user but signed by itself. We present a formal model to capture such a scheme and provide a concrete construction.     

Microbially mediated phosphine emission

There is still a lot of controversy in literature concerning the question whether a biochemical system exists enabling micro-organisms to reduce phosphate to phosphine gas. The search for so-called 'de novo synthesised' phosphine is complicated by the fact that soils, slurries, sludges, etc., which are often used as inocula, usually contain matrix bound phosphine (MBP). Matrix bound phosphine is a general term used to indicate non-gaseous reduced phosphorus compounds that are transformed into phosphine gas upon reaction with bases or acids. A study was carried out to compare the different digestion methods, used to transform matrix bound phosphine into phosphine gas. It was demonstrated that caustic and acidic digestion methods should be used to measure the matrix bound phosphine of the inoculum prior to inoculation to avoid false positive results concerning de novo synthesis. This is especially true if anthropogenically influenced inocula possibly containing minute steel or aluminium particles are used. The comparative study on different digestion methods also revealed that the fraction of phosphorus in mild steel, converted to phosphine during acid corrosion depended on the temperature. Following these preliminary studies, anaerobic growth experiments were set up using different inocula and media to study the emission of phosphine gas. Phosphine was detected in the headspace gases and its quantity and timeframe of emission depended on the medium composition, suggesting microbially mediated formation of the gas. The amount of phosphine emitted during the growth experiments never exceeded the bound phosphine present in inocula, prior to inoculation. Hence, de novo synthesis of phosphine from phosphate could not be demonstrated. Yet, microbially mediated conversion to phosphine of hitherto unknown reduced phosphorus compounds in the inoculum was evidenced.