科学团队理论及其对大型仿真研究的启示

科学团队理论主要针对大型科学研究与项目研发中,各跨学科、交叉学科群体之间的管理和组织等问题。大型仿真研究和工程项目涉及许多不同部门和专业,其管理与技术起着同样重要作用。为此总结了科学团队理论的发展及应用现状,结合仿真工程的特点提出r将科学团队理论应用于仿真研究的一些设想,并以非常规突发事件应急管理仿真平台的研究为例介绍了科学团队理论在大型仿真研究中应用的过程。     

海港流量计检定信息系统的设计与使用

在随着"黄蓝"战略的实施,东营港油码头的建设,对大口径流量需求日益增加,根据流量检定站管理的需要成功开发出"流量计检定信息系统",实现了流量计检定数据采集、报告数据处理及证书出具、管理部门审批和发放报告到各受检单位查询等全流程网络化管理.建立流量计检定数据、证书管理信息数据库,为石油储运、销售等管理部门提供了实时查询,检定数据的高效利用服务.     

一级直线倒立摆匀速行走的模糊控制研究与实现

当前针对倒立摆的研究一般是把角度控制或者位置控制作为控制目标,很少着眼于速度控制,有鉴于此,设计了一种简单的模糊控制器,应用于一级直线倒立摆的匀速行走控制中;仿真实验和实物实时控制实验均验证了该控制器的有效性,对于设定的速度整定值,通过调整几个比例环节的系数,系统具有很好的动态性能指标,而且控制器在有外界扰动时体现了很好的抗扰性;考虑到实际物理系统中倒立摆行程的限制,设计的自动换向开关实现了倒立摆在一段给定的行程上匀速来回行走的控制目标,通过手动切换开关也能实现倒立摆的位置控制。     

特定三维人脸建模方法综述

介绍人脸建模的研究背景、研究内容以及研究热点,总结近期三维人脸建模的常用方法及优缺点,展望今后人脸建模的研究方向。三维建模是计算机视觉和计算机图形学领域中一个基本的问题,人脸因其普遍性和特殊性,成为众多研究人员的研究目标。     

合谷刺配合恢刺阿是穴治疗血瘀型腰椎间盘突出症临床研究

摘 要:目的 观察合谷刺配合恢刺阿是穴对血瘀型腰椎间盘突出症(Lumbar disc herniation,LDH)患者的临床疗效及对腰椎功能日本骨科协会评估治疗评分（Japanese Orthopaedic Association Scores,JOA）、McGill疼痛量表、疼痛视觉模拟评分(Visual Analogue Scale,VAS)及患者血清(5-hydroxytryptamine,5-HT)、P物质(Substance P,SP)的影响。方法 采用随机数字表法将80例血瘀型LDH患者随机分为合谷刺配合恢刺阿是穴组(治疗组)及常规针刺组(对照组),每组40例。治疗组常规选穴行合谷刺法,在此基础上配合恢刺局部压痛点;对照组采用平补平泻法。两组均隔日治疗1次,5次为1疗程,共3疗程。疗程结束后进行综合疗效评价及腰椎功能JOA评分、McGill疼痛量表、VAS及血清5-HT、SP比较。结果 治疗组总有效率为89.18%,对照组为64.86%;与治疗前比较,两组治疗后腰椎功能JOA评分升高,McGill疼痛量表、VAS评分及血清5-HT、SP均降低。结论 合谷刺配合恢刺阿是穴较常规针刺更能有效缓解血瘀型LDH疼痛,提高腰椎功能活动度,从而改善临床症状,值得临床进一步推广。     

One-Component Artificial Gustatory System Based on Hydrogen-Bond Organic Framework for Discrimination of Versatile Analytes

Hydrogen-bond organic frameworks (HOFs) with excellent structural and luminescent properties have emerged as a promising material for the construction of fluorescence sensors. However, designing a facile, universal and high throughput sensor with multiplex detection capacity still remains challenging. Herein, a one-component sensor array is constructed that mimics natural gustatory system for accurate and high-throughput discrimination and identification of versatile analytes. HOF as a single sensing element greatly simplifies the probe preparation in sensor array and detection procedure. Metal ions, proteins and bacteria as the model targets are rapid and accurately discriminated, presenting the universality of the system. Particularly, the system is successfully used for the classification of antibiotic mechanisms. The study expands the application scope of HOFs and provides a facile and universal system for sensing applications.     

Pre-Protonated Vanadium Hexacyanoferrate for High Energy-Power and Anti-Freezing Proton Batteries

Proton batteries have been considered as an innovative energy storage technology owing to their high safety and cost-effectiveness. However, the development of fast-charging proton batteries with high energy/power density is greatly limited by feasible material selection. Here, the pre-protonated vanadium hexacyanoferrate (H-VHCF) is developed as a proton cathode material to alleviate the capacity loss of proton-free electrode materials during electrochemical tests. The pre-protonation process realizes fast and long-distance transport of protons by shortening diffusion path and reducing migration barriers. Benefitting from the enhanced hydrogen bonding network combined with dual redox reactions of V and Fe in protonated H-VHCF cathode, a high energy density of 74 Wh kg⁻¹ at 1.1 kW kg⁻¹, and a maximum power density of 54 kW kg⁻¹ at 65 Wh kg⁻¹ is achieved for the asymmetric proton batteries coupling with MoO₃/MXene anode. Proton transport and double oxidation-reduction center are verified by theoretical calculations and ex situ experimental measurements. Considering the anti-freezing availability of proton batteries, 82.5% of its initial capacity is maintained after 10000 cycles under −40 °C at 0.5 A g⁻¹. As a proof-of-concept, flexible device fabricated by optimized electrodes and hydrogel electrolytes can power up a light-emitting diode even under a bent state.     

直驱式永磁同步电机改进型无差拍直接转矩控制研究

为提高直驱式永磁同步电机（DD-PMSM）的动态响应性能,提出了一种改进型无差拍直接转矩控制(DB-DTC)策略。改进型DB-DTC在保留传统DB-DTC动态响应性能的基础上,简化了控制过程,降低了实时计算量。通过在MATLAB/Simulink 环境下搭建仿真模型,对传统DB-DTC和改进型DB-DTC的控制效果进行对比,并将改进型DB-DTC结合位置型阻抗控制策略,验证控制策略的优越性。仿真结果表明,在位置控制模式下,相对于传统DB-DTC,所提控制策略的电机转动至给定角度以及转速降为零所需的时间减少0.002 s,稳态运行角度误差减少0.02°。在速度控制模式下,相对于传统DB-DTC,所提控制策略的电机达到给定转速的时间减少0.004 s,稳态转速误差降低0.03 r/min,稳态转速波动降低0.06 r/min,在电机进入稳态运行以后,q轴电流峰值降低0.193 A,q轴的电流脉动降低0.204 A。电机控制系统具有更好的动态性能和更强的抗干扰能力。     

Pathogen-mimicking nanocomplexes: self-stimulating oxidative stress in tumor microenvironment for chemo-immunotherapy

A novel drug-loaded pathogen-mimicking nanocomplex (MSN-DOX-SP-LPS) has been constructed for synergistic chemo-immunotherapy.

     

Regulation of cell fate by near infrared-responsive telomerase activity

Here we develop a strategy using near infrared (NIR) modulation of telomerase activity based on gold nanocage@smart polymer system. Using this biocompatible design, we can regulate cellular behavior. This system has been used in vivo by taking advantages of NIR. This is the first example for optical modulation of telomerase activity in living cells and tissues.