蛋类膜-壳结构启发制备兼具高灵敏度和宽检测范围的应变传感

为了解决可拉伸应变传感器的灵敏度与检测范围(最大和最小可拉伸性)之间相互制约的问题.受蛋类膜-壳结构的启发,本文提出了一种构筑具有高灵敏度、宽可拉伸应变传感器的新策略,即基于柔性可拉伸的表面接枝聚吡咯膜(s-PPy)(类似于蛋膜)和脆性金膜(类似于蛋壳)制备器件.Au和s-PPy膜在电学和机械性能上产生相互协同作用.A...     

Terahertz Direct Modulation Techniques for High-speed Communication Systems

Terahertz communication technology can provide abundant frequency resources,strong confidentiality,antijamming capability,communication tracking capability and ...     

某宾馆空调冷热源方案比较

通过比较三种方案的初投资和运行费用,得出最佳的冷热源方案。     

Maternal Prenatal Inflammation Increases Brain Damage Susceptibility of Lipopolysaccharide in Adult Rat Offspring via COX-2/PGD-2/DPs Pathway Activation

A growing body of research suggests that inflammatory insult contributes to the etiology of central nervous system diseases, such as depression, Alzheimer’s disease, and so forth. However, the effect of prenatal systemic inflammation exposure on offspring brain development and cerebral susceptibility to inflammatory insult remains unknown. In this study, we utilized the prenatal inflammatory insult model in vivo and the neuronal damage model in vitro. The results obtained show that prenatal maternal inflammation exacerbates LPS-induced memory impairment, neuronal necrosis, brain inflammatory response, and significantly increases protein expressions of COX-2, DP2, APP, and Aβ, while obviously decreasing that of DP1 and the exploratory behaviors of offspring rats. Meloxicam significantly inhibited memory impairment, neuronal necrosis, oxidative stress, and inflammatory response, and down-regulated the expressions of APP, Aβ, COX-2, and DP2, whereas significantly increased exploring behaviors and the expression of DP1 in vivo. Collectively, these findings suggested that maternal inflammation could cause offspring suffering from inflammatory and behavioral disorders and increase the susceptibility of offspring to cerebral pathological factors, accompanied by COX-2/PGD-2/DPs pathway activation, which could be ameliorated significantly by COX-2 inhibitor meloxicam treatment.     

浅谈混水直供供热方式的运行特征及经济性

本文主要是对混水直供供热方式在实际应用中的运行特征进行阐述探讨,混水直供供热方式工艺结构简洁、二次网静压定压方式独特—回水阀门定压、运行稳定经济、供热效果良好,重点对混水直供供热方式的运行特征阐述及相对间接供热方式的经济比较分析。     

测试条件对聚氯乙烯树脂稀溶液粘数的影响

聚氯乙烯树脂稀溶液粘数是聚氯乙烯树脂的一项重要指标,它的高低决定着产品的不同用途。本实验测试了几种不同测试条件如测试温度、黏度计毛细管直径、溶剂浓度等对聚氯乙烯树脂稀溶液粘数结果所产生的影响,通过实验数据的理论分析和计算,对原因进行了具体的分析。这些分析结果的获得对提高粘数分析的准确性,对于指导实际生产,规范检验操作,修订检验标准都有着重要的意义。     

MicroRNAs as Potential Biomarkers in the Differential Diagnosis of Lipomatous Tumors and Their Mimics

Adipocytic tumors are the most common subtype of soft tissue tumors. In current clinical practice, distinguishing benign lipomas from well-differentiated liposarcomas (WDLPS), as well as dedifferentiated liposarcomas (DDLPS) from their morphologic mimics, remains a significant diagnostic challenge. This is especially so when examining small biopsy samples and without the aid of additional ancillary tests. Recognizing the important role that microRNAs (miRNAs) play in tumorigenesis and their potential utility in tumor classification, we analyzed routine clinical tissue samples of benign and malignant lipomatous tumors, as well as other sarcoma mimics, to identify distinguishing miRNA-based signatures that can aid in the differential diagnosis of these entities. We discovered a 6-miRNA signature that separated lipomas from WDLPS with high confidence (AUC of 0.963), as well as a separate 6-miRNA signature that distinguished DDLPS from their more aggressive histologic mimics (AUC of 0.740). Functional enrichment analysis unveiled possible mechanistic involvement of these predictive miRNAs in adipocytic cancer-related biological processes and pathways such as PI3K/AKT/mTOR and MAPK signaling, further supporting the relevance of these miRNAs as biomarkers for adipocytic tumors. Our results demonstrate that miRNA expression profiling may potentially be used as an adjunctive tool for the diagnosis of benign and malignant adipocytic tumors. Further validation studies are warranted.     

边际油田群的综合开发

本文回顾了国内外海上边际油田群的开发状况,从减少开发投资和提高油田群开发的经济性出发,提出了适合边际油田综合开发的技术和开发策略,简要介绍了边际油田群综合开发的最新研究动态。