PALAEOZOIC TECTONIC HISTORY OF SE TURKEY

A review of published data for the Palaeozoic of SE Turkey, together with facies distribution and palaeo-fault maps derived from regional field data, are used to interpret the Palaeozoic tectonic history of the region.
Intracratonic rifting events in the Early Cambrian and the Early Ordovician led to syn-rift deposition within fault-bounded basins. Marine transgressions across the region in the mid-Cambrian and mid-to-Late Ordovician were probably influenced by regional thermal subsidence after each rifting event, in addition to (glacio-)eustatic mechanisms. Marine transgressions in the Early Silurian and Early Carboniferous are thought to have been entirely eustatic in origin.
Poorly-constrained, Late Palaeozoic facies variations across the region can be related to uplift during the Caledonian and Hercynian orogenic episodes. Widespread tilting and erosion before the Cretaceous, which has removed much of the Late Palaeozoic record from this region, resulted from uplift at the edges of a major rift system which was initiated during the Triassic-to-Jurassic opening of the Southern Neotethys.     

Toward a theory of robust compensation for systems with unknownparasitics

The problem of designing a robust compensator based on a plant model with order uncertainty is considered. The uncertainty is characterized mathematically as a class of generalized singular perturbations of the plant. The case of static compensation is examined. A necessary and sufficient condition is established under which actual closed-loop behavior is close to that predicted by the plant model under sufficiently small singular perturbations. The condition is shown to be generic     

POEMS: program for outliers elimination in multidimensional space

A Program for Outliers Elimination in Multidimensional Space (POEMS), which allows the user to eliminate outliers from training spaces as a prior step to any statistical study, is presented. Even though the program can be applied to any scientific field, the characteristics of POEMS makes it particularly suitable for 'series design' on Quantitative Structure-Activity Relationships studies.     

The Macintosh Programmer's Workshop

The authors discuss the Macintosh Programmer's Workshop (MPW), a Macintosh development environment that includes a comprehensive set of programming tools and handles several languages. It also combines the graphical interface common to all Macintosh applications, a command language similar to the Unix shell languages, and Smalltalk's immediate execution of commands in any window. They focus on the program-development environment rather than on the tools in that environment. They give the history of MPW, and describe its design goals. The bulk of the article is a discussion of MPW's design     

Liquid–liquid extraction of a recombinant protein with reverse micelles

Recombinant cytochrome b₅ was extracted into the reversed micelle phase of an anionic surfactant (AOT) in octane and back-extracted to a final aqueous phase. The extraction of the protein was controlled by an electrostatic mechanism, since it was dependent on the global charge of the protein. This was directly demonstrated by experiments with native and mutant cytochromes obtained by site directed mutagenesis. The back-extraction of cytochrome b₅ to a fresh aqueous phase was decreased by factors that reduced the size of the water pool of the organic phase, such as high salt concentrations (1–2 mol dm^?3 NaCl) and low temperatures (4°C), probably because of an increase in a favourable interaction of this protein with the surfactant at closer distances.     

A Macintosh Hypercard stack for calculation of thermodynamically-corrected buffer recipes

This paper describes a stack for the Apple Macintosh Hypercard environment that facilitates the calculation of a set of thermodynamically-corrected pH buffers. Presented in the familiar Macintosh mouse-based environment, the program allows comprehensive buffer design and gives the user full control of buffer species, temperature, ionic strength, pH and choice of counter-ion to maintain the ionic strength at a fixed value. Addition of new buffers to the stack is straightforward and the recipes that are generated, including the weights of the various components, can be displayed on the screen or saved to a disk file for subsequent printing.