Synthesis of Cu–CdIn2O4 nanoparticles decorated on nickel foam as a sensitive non-enzymatic electrochemical sensor for glucose detection

Fast and effective detection of glucose has important significance in clinical medicine and the diagnosis of diabetes. Electrochemical non-enzymatic glucose sensor has received extensive attention to detect glucose in the recent years due to its simple operation and low cost. In this paper, Cu–CdIn₂O₄ nanoparticles decorated on nickel foam electrode as a sensitive non-enzymatic electrochemical sensor for glucose detection are synthesized by a one-step non-aqueous sol–gel method. Different Cu-doping levels are designed as performance comparison analysis. The electrocatalytic performance of the Cu–CdIn₂O₄ nanoparticles/Ni foam electrodes towards glucose oxidation is evaluated by cyclic voltammetry and current time. The results show that 15% Cu–CdIn₂O₄/Ni foam electrode shows higher sensitivity, as well as an excellent anti-interference and long-term stability towards glucose detection compared with 10% and 20% Cu–CdIn₂O₄/Ni foam electrodes. Hence, 15% Cu–CdIn₂O₄/Ni foam can be regarded as an efficient and a promising sensing material for glucose detection. Such satisfactory performance is not only attributed to the synergistic effect of Cd, In, and Cu, but also benefits from the uniform distribution of 15% Cu–CdIn₂O₄ nanoparticles on the Ni foam, which provides more reactive sites for the electrochemical catalytic reaction.

     

The Discovery of LML134, a Histamine H3 Receptor Inverse Agonist for the Clinical Treatment of Excessive Sleep Disorders

Histamine H3 receptor (H3R) inverse agonists that have been in clinical trials for the treatment of excessive sleep disorders, have been plagued with insomnia as a mechanism-based side effect. We focused on the identification of compounds that achieve high receptor occupancy within a short time, followed by rapid disengagement from the receptor, a target profile that could provide therapeutic benefits without the undesired side effect of insomnia. This article describes the optimization work that led to the discovery of 1-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)piperidin-4-yl 4-cyclobutylpiperazine-1-carboxylate ( 18 b , LML134).     

聚烯烃材料粘合剂的研制

本文以热塑性橡胶溶于适当的溶剂并配以松香和２４０２树脂等增粘剂，研制出聚烯烃材料粘合剂。该胶具有稳定性好，粘接强度高，固化快和使用方便等特点。     

老挝南椰2水电工程长距离调引水开发方案的研究

通过对老挝南椰2水电站长距离调引水方案的研究,对该工程的引水规模、主水库正常蓄水位和死水位、装机容量及发电引水隧洞进行了系统分析和技术经济对比,选择了电站综合效益最优的工程开发方案。     

螺栓的冲击载荷分析

预紧螺栓所受拉力可根据力平衡和螺拴与被联接零件间的变形协调条件确定，其大小变化量为外加载荷变化量的几分之一。但当外加载荷是通过几个联接处有较大间隙的零件传递至螺栓时，这种分析方法就不再适用。由于间隙的存在，零件间的运动速度不协凋，间隙消除时必然产生冲击，使螺栓承受冲击载荷。准确计算冲击载荷的大小对于螺栓的使用安全具有重要意义。某离合器式螺旋压力机的预紧联接螺栓，承受着螺杆和滑块重量、平衡回程缸下推力以及滑块回程制动期间较强的冲击力。文中通过分析制动期间螺旋副的冲击过程，建立螺栓变形的数学模型，导出冲击载荷解析式，提出降低冲击载荷的措施，为离合器式螺旋压力机回程制动机构的设计提供重要的参考，同时也为承受大惯性负载的螺旋机构的受力分析提供参考。     

Lithiothermic-Synchronous Construction of Mo-Li2S-Graphene Nanocomposites for High-Energy Li2S//Si?C Battery

Reducing the activation barrier and stabilizing the sulfur species of Li₂S cathodes can ultimately enhance cell efficiency and the cycle life of S-based Li-ion batteries (LIBs). Here, a unique synchronous synthesis method is established that can simultaneously construct Li₂S encapsulated in conductive protective layers, and accordingly propose a coordination effect of catalysis and domain restriction for Li₂S cathodes. Typically, based on the lithiothermic reaction of 8Li + MoS₂ + CS₂ = 4Li₂S + Mo + C, the obtained composite features abundant Mo nanocrystals embedded in crystalline Li₂S matrices and then wrapped by few-layer graphene. Notably, all three components derived from lithiothermic reaction are linked by the chemical bonding of Mo? S and C? S, forming a compact Mo-Li₂S-graphene triple heterostructure. Systematic studies reveal an unprecedented relevancy between charge overpotential and catalytic activation of Mo-Li₂S-graphene, whereas a low activation potential of 2.43 V is achieved. Further studies disclose the relationship between cycle stability and confinement effect of core-shell structure, whereas the improved confinement efficiency for polysulfides enables an excellent cycle life for the Li-S battery. Moreover, the Mo-Li₂S-graphene cathode demonstrates promising application for LIB, where the Mo-Li₂S-graphene//Si? C battery shows a high capacity of 764 mAh g^?1 and outstanding cycle stability.     

基于自适应神经网络系统聚类的特殊负荷分类研究

根据特殊负荷调查统计信息,甄别不同聚类分析的优缺点,提出了一种基于自适应神经网络系统聚类的特殊负荷分类方法,分别从负荷特性、供电可靠性与电能质量3个维度建立聚类指标,并以78个特殊负荷为样本进行聚类分析。结果表明,该方法快速有效,同类特殊负荷相似度高,各类特殊负荷之间差异明显。该分类方法可推广至典型特殊行业负荷分类,为配电网对特殊负荷采用相应的供电措施提供理论依据,便于供电部门制定特殊负荷供电服务。     

Cantilever dynamics and quality factor control in AC mode AFM height measurements

We show that inconsistent-imaging dynamics, in which the cantilever oscillates in the attractive regime on substrate background but in the repulsive regime on sample, leads to artifacts in apparent height in AC mode Atomic force microscopy. Active Q control can be used to effectively tune the imaging dynamics. Increased effective Q promotes the attractive regime, improves imaging sensitivity, and results in less invasive imaging of soft biological molecules.     

2008奥运羽毛球热身馆单层网壳稳定分析的ANSYS二次开发及其应用

针对ANSYS中Beam188单元,通过程序二次开发解决了大规模单元端部释放问题,建立钢结构网壳ANSYS分析模型,进行了非线性屈曲分析,得出了在大跨度钢结构网壳设计中,采用Beam188单元能够得到真实的模拟效果。     

Enhanced charge separation of CuS and CdS quantum-dot-cosensitized porous TiO2-based photoanodes for photoelectrochemical water splitting

Photoelectrochemical (PEC) water splitting using high-performance catalysts shows considerable promise in generating environment-friendly hydrogen energy. Its practical applications, however, suffer from several shortcomings, such as low photocurrent density, large onset-voltage value, and poor durability. In this study, CuS and CdS quantum-dot-cosensitized porous TiO₂-based PEC catalysts (CuS-CT) have been successfully synthesized via in situ sulfuration of CuO and CdO coexisting inside a porous TiO₂ monolith by a hydrothermal method. Compared to porous TiO₂, CuS-sensitized porous TiO₂ (CuS-TiO₂), and CdS-sensitized porous TiO₂ (CdS-TiO₂) in terms of PEC performance, the CuS-CT photoanode exhibited a significantly high anodic photocurrent for water splitting under simulated sunlight radiation. The photocurrent produced by the optimized sample of 7% CuS-5% CdS-TiO₂ (7% CuS-CT) was nearly 2.7 times higher than that of pure porous TiO₂ at 1.0 V versus a reversible hydrogen electrode (RHE). Porous TiO₂ possesses large surface areas that can drive fast electrolyte transport and afford more surface reaction active sites. On the other hand, CuS and CdS quantum dots not only broaden the visible light absorption range, but also improve photoinduced electron-hole separation efficiency. The co-sensitized multi-nanostructures photoanodes lead to a remarkable and promising application in PEC water splitting reactions.