全文获取类型
收费全文 | 486篇 |
免费 | 3篇 |
国内免费 | 7篇 |
专业分类
电工技术 | 19篇 |
综合类 | 7篇 |
化学工业 | 15篇 |
金属工艺 | 29篇 |
机械仪表 | 12篇 |
建筑科学 | 51篇 |
矿业工程 | 2篇 |
能源动力 | 15篇 |
轻工业 | 28篇 |
石油天然气 | 8篇 |
无线电 | 16篇 |
一般工业技术 | 16篇 |
冶金工业 | 267篇 |
自动化技术 | 11篇 |
出版年
2022年 | 1篇 |
2020年 | 1篇 |
2018年 | 4篇 |
2017年 | 2篇 |
2014年 | 5篇 |
2013年 | 7篇 |
2012年 | 15篇 |
2011年 | 33篇 |
2010年 | 14篇 |
2009年 | 18篇 |
2008年 | 2篇 |
2007年 | 9篇 |
2006年 | 14篇 |
2005年 | 6篇 |
2004年 | 17篇 |
2003年 | 23篇 |
2002年 | 23篇 |
2001年 | 15篇 |
2000年 | 5篇 |
1999年 | 24篇 |
1998年 | 50篇 |
1997年 | 50篇 |
1996年 | 34篇 |
1995年 | 28篇 |
1994年 | 15篇 |
1993年 | 12篇 |
1992年 | 8篇 |
1991年 | 8篇 |
1990年 | 8篇 |
1989年 | 7篇 |
1988年 | 3篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1982年 | 1篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1977年 | 3篇 |
1976年 | 16篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1972年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有496条查询结果,搜索用时 0 毫秒
91.
The autosomal recessive mouse mutation sarcosinemia (sar), which was discovered segregating in the progeny of a male whose premeiotic germ cells had been treated with the mutagen ethylnitrosourea, is characterized by a deficiency in sarcosine dehydrogenase activity. Using an intersubspecific cross, we mapped the sar locus to mouse chromosome 2, approximately 15-18 cM from the centromere. The genetic localization of this locus in the mouse allows the identification of a candidate region in human (9q33-q34) where the homologous disease should map. 相似文献
92.
D Adu A Pall RA Luqmani NT Richards AJ Howie P Emery J Michael CO Savage PA Bacon 《Canadian Metallurgical Quarterly》1997,90(6):401-409
Intraperitoneal and intracranial inoculation of herpes simplex virus type 2 (HSV 2) into BALB/cN and C57BL/6N mice was carried out to induce experimental myelitis. The myelitis was clearly observed in C57BL/6N mice following intraperitoneal inoculation. Within 24 hours before death, the mice showed urinary and rectal incontinence and paraplegia of the hind legs. Randomly distributed, severe necrosis was demonstrated in the spinal cord, mainly at the lower cord. In BALB/cN mice the clinical symptoms were not clearly observed, as the mice died shortly after their onset. Although spinal cord necrosis was more prominent in C57BL/6N mice than BALB/cN mice, brain necrosis was only found in the latter, and not in the former. Both strains of mouse showed marked nuclear pyknosis of the nerve cells and slight nuclear pyknosis of the astrocytes in the brain where HSV 2 antigen was demonstrated immunohistochemically. The antigen was also detected in the necrotic spinal cord. In contrast, intracranial inoculation of the virus into both strains did not cause myelitis. Spinal cord necrosis was not demonstrated and virus DNA was not detected, by PCR, in spinal cord samples. In the brain, however, the virus was demonstrated by both PCR and immunohistochemistry. 相似文献
93.
CO Dummett 《Canadian Metallurgical Quarterly》1996,44(3):111-114
In order to study the influence of ageing on the hormonal function of the endothelium in man, plasma endothelin levels were measured in 11 normal young persons (mean aged 25.7 +/- 1.8 years) and in 16 apparently healthy elderly subjects (mean 87.5 +/- 5.4 years) without anamnestic or clinical signs of symptomatic atherosclerosis. The mean plasma level +/- SD of endothelin was 2.72 +/- 0.61 pg/ml in elderly subjects and 2.09 +/- 0.66 in young subjects. The difference was statistically significant (p < 0.05). Various humoral or local age-related environmental factors may be responsible for this result. In particular increased vascular production of endothelin may be the response to endothelial cell damage caused by an asymptomatic atherosclerotic process. Studies still need to define whether enhanced plasma endothelin levels in elderly subjects not suffering from symptomatic atherosclerosis are the consequence of ageing alone or an ongoing but clinically silent atherosclerotic process. 相似文献
94.
Porins are trimeric proteins that constitute water-filled pores that allow transmembrane diffusion of small solutes through the outer membrane layer of gram-negative bacteria. The porins are capable of inserting into the membranes of eucaryotic cells, and in the present study we have examined the in vitro effects on neutrophil functions of the following purified porins: meningococcal outer membrane protein classes 1 and 3 and gonococcal outer membrane protein 1B (P1B). The neisserial porins inhibited human neutrophil chemoattractant-induced actin polymerization and degranulation of both primary and secondary granules. The neutrophil expression of immunoglobulin G (IgG) Fc receptors II (Fc gamma RII; CDw32) and III (Fc gamma RIII; CD16), as well as the activation-dependent downregulation of Fc gamma RIII, were reduced by the meningococcal and gonococcal porins. The neisserial porins impaired the upregulation of complement receptors 1 (CD35) and 3 (CD11b) and inhibited the phagocytic capacity of neutrophils, as evaluated by the uptake of meningococci (strain 44/76) in the presence of patient serum containing known amounts of IgG against meningococcal porins. The porins also primed neutrophils to increase their intracellular hydrogen peroxide production in response to FMLP, whereas no such priming was observed if the neutrophil protein kinase C was stimulated directly with phorbol myristate acetate. The neisserial porins influenced neutrophil functions in a time- and concentration-dependent manner. The meningococcal class 1 outer membrane protein and the gonococcal P1B tended to alter neutrophil functions more than the meningococcal class 3 protein. Thus, the neisserial porins inhibited human neutrophil actin polymerization, degranulation, opsonin receptor expression, and phagocytosis but primed the neutrophils to increase their oxidative burst. It remains to be determined whether these in vitro observations reflect mechanisms that may be of importance for the interaction between neutrophils and Neisseria species in vivo. 相似文献
95.
96.
1. The effect of glyburide (glibenclamide) treatment on the liver glycogen levels of diabetic rats have been studied. 2. 3 weeks treatment with glyburide (5 mg/kg, orally) increased liver glycogen and decreased blood glucose levels. 3. The results of this study demonstrated that the sulfonylurea, glyburide is capable of exerting direct insulin-like effects on liver glycogen values in vivo. 相似文献
97.
98.
99.
100.
扩口成型机在塑型管材生产线中属关键设备,本文探讨可编程控制器(PLC)及其温控模块在加热成型机中的实现技术,以及图示操作终端在加工设备中的应用。根据扩口成型机顺序控制的特点以及PLC及其组件齐全的硬件配置和软件功能,有针对性地具体研究扩口成型机的硬件配置和软件编制。 相似文献