Effect of ligand passivation on morphology,optical and photoresponse properties of CdS colloidal quantum dots thin film

In the present report, cadmium sulfide (CdS) colloidal quantum dots (CQDs) with average diameter of 6 nm were synthesized by using oleylamine as ligand and solvent. The insulating oleylamine ligands form barriers around the CdS CQDs to decrease carrier mobility. In order to remove the ligands and improve the photoelectrical properties of the closed-packed film, ethanedithiol, mercaptopropionic acid and cetyltrimethylammonium bromide (CTAB) were applied for solid state ligand exchange. CTAB treated film had the fastest 3 dB bandwidth of 144.7 Hz and yielded the highest detectivity of 1.37 × 10⁸ Jones. The excellent properties of ligand passivation have important application in nanocrystals based electronic and optoelectronic devices.     

Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles

A main challenge to broaden the biomedical application of CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) genome editing technique is the delivery of Cas9 nuclease and single‐guide RNA (sgRNA) into the specific cell and organ. An effective and very fast CRISPR/Cas9 genome editing in vitro and in vivo enabled by bioreducible lipid/Cas9 messenger RNA (mRNA) nanoparticle is reported. BAMEA‐O16B, a lipid nanoparticle integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing as fast as 24 h post mRNA delivery. It is demonstrated that the simultaneous delivery of Cas9 mRNA and sgRNA using BAMEA‐O16B knocks out green fluorescent protein (GFP) expression of human embryonic kidney cells with efficiency up to 90%. Moreover, the intravenous injection of BAMEA‐O16B/Cas9 mRNA/sgRNA nanoparticle effectively accumulates in hepatocytes, and knocks down proprotein convertase subtilisin/kexin type 9 level in mouse serum down to 20% of nontreatment. The leading lipid nanoparticle, BAMEA‐O16B, represents one of the most efficient CRISPR/Cas9 delivery nanocarriers reported so far, and it can broaden the therapeutic promise of mRNA and CRISPR/Cas9 technique further.     

Therapy for cerebral ischemic injury with erythropoietin-containing nanoparticles

In this study we prepared nanocarrier of erythropoietin (EPO) and the curative effect of the EPO-containing nanoparticles for periventricular leukomalacia (PVL) model was validated. It was demonstrated that EPO-containing nanoparticles can ameliorate drug-induced liquefaction caused by hypoxia. EPO-containing nanomedicine may open new therapeutic strategies in hypoxia cure.     

基于顾客现状偏好的供应链无理由退货策略

首次将顾客现状偏好因素引入到供应链无理由退货策略中,主要研究了当制造商和零售商之间存在回扣契约或销售折扣契约时,供应链及其成员的最优无理由退货策略问题。文中通过对供应链无理由退货策略进行建模分析,分别得出了在不同契约中供应链整体和零售商的最优退货价格以及二者的双边际效益情况,并且发现了部分契约可以通过调整契约参数来消除这种矛盾边际效益现象,以此来实现供应链的协调。     

Organic Ferroelectric‐Based 1T1T Random Access Memory Cell Employing a Common Dielectric Layer Overcoming the Half‐Selection Problem

Organic electronics based on poly(vinylidenefluoride/trifluoroethylene) (P(VDF‐TrFE)) dielectric is facing great challenges in flexible circuits. As one indispensable part of integrated circuits, there is an urgent demand for low‐cost and easy‐fabrication nonvolatile memory devices. A breakthrough is made on a novel ferroelectric random access memory cell (1T1T FeRAM cell) consisting of one selection transistor and one ferroelectric memory transistor in order to overcome the half‐selection problem. Unlike complicated manufacturing using multiple dielectrics, this system simplifies 1T1T FeRAM cell fabrication using one common dielectric. To achieve this goal, a strategy for semiconductor/insulator (S/I) interface modulation is put forward and applied to nonhysteretic selection transistors with high performances for driving or addressing purposes. As a result, high hole mobility of 3.81 cm² V^?1 s^?1 (average) for 2,6‐diphenylanthracene (DPA) and electron mobility of 0.124 cm² V^?1 s^?1 (average) for N ,N ′‐1H,1H‐perfluorobutyl dicyanoperylenecarboxydiimide (PDI‐FCN₂) are obtained in selection transistors. In this work, we demonstrate this technology's potential for organic ferroelectric‐based pixelated memory module fabrication.     

基于Modbus协议的S7-200 PLC与矿用智能遥控接收机的通信

介绍了Modbus协议的特点,分析了S7-200 PLC Modbus RTU主站协议库,确定了采掘设备控制器S7-200 PLC与矿用智能遥控接收机的数据通信采用Modbus RTU协议,实现了采掘设备与遥控装置的双向通信。应用结果表明,以S7-200 PLC为主站的Modbus通信,传输数据准确可靠,效果良好。     

水性超支化聚氨酯丙烯酸酯的合成及性能研究

以TDI、HPA、丁二酸酐、超支化聚酯为原料,合成了一种新型可紫外光固化的水性超支化聚氨酯丙烯酸酯,用FT-IR跟踪研究了合成过程基团的变化.测试了超支化预聚体水溶液粒径,结果表明该粒径随丁二酸酐含量的增加而减小.对固化膜的力学性能测试和热重分析测试结果表明,随着超支化聚氨酯丙烯酸酯中端丙烯酸酯基含量的增加,固化膜的热...     

Newton法对应单参有理函数族的广义M-J集

讨论了Newton法对应单参数有理函数族的广义Mandelbrot集和Julia集,给出了它们的构造算法,证明了其广义Mandelbrot集的有界性,并给出了其周期点个数的计算公式.利用数学实验的方法研究了广义Mandelbrot集周期芽苞分布规律,并通过对比分析得到了它们与z~n+c的Mandelbrot集和Julia集之间的族相似性类似的新的族相似关系.文中算法为Mandelbrot集和Julia集的发展提供了新的思路.     

甚高速数字用户线VDSL技术

VDSL是正在发展中的利用现有铜双绞电话线传输宽带数据的新技术。本文对其容量、结构、支撑技术、标准化现状、与ADSL的关系等进行了介绍。     

认知无线电网络中的一种新型协作频谱感知方法

提出一种能够应用于认知无线电网络中的新型协作频谱感知方法--双阚值能量检测,该方法同时利用了次要用户的接收信号能量和局部判决结果两种信息,由判决中心结合次要用户的局部判决结果和接收信号能量,做出最终判决从而确定主要用户存在与否.该方法在通信流量增加不多的情况下能够充分提升检测性能.仿真结果表明当接收信号能量落入延迟判决区间的概率较大时,该算法能够显著地改善认知无线电网络的协作频谱感知能力.