苯并口恶嗪-环氧化合物-胺类催化剂体系开环聚合反应的研究

采用TLC，GPC，1H－NMR及IR等分析方法，对苯并恶嗪－环氧化合物－胺类催化剂体系的聚合反应进行了研究，表征了产物结构，并探讨了聚合反应机理，结果表明，苯并恶唪－环氧化合物体系在胺类催化剂如苄胺，咪唑的作用下，能发生开环聚合反应，生成低分子量的聚合物。     

SPAC系统中水热CO2通量光合作用的综合模型（Ⅱ）：模型验证

本文利用禹城综合试验站土壤－植物－大气连续体系综合观测场冬小麦田实测资料，对“SPAC系统中水热、CO2通量与光合作用的综合模型（Ⅰ）模型建立”一文所建立的模型土壤水分动态、蒸发蒸腾和冠层CO2通量等功能进行了验证，利用波文比观测水汽通量结果、土壤水分剖面监测结果分别与对模拟计算腾发量和土壤水分剖面的验证结果表明，模拟计算的腾发量和土壤水分剖面是比较准确的；将模拟的光合作用过程中的CO2通量与实测值对比表明，模拟值与实测值的变化趋势是一致的，但是数据上存在一定的差异，模拟光合作用过程和强度符合一般规律，总体说明，所建立的系统模型在上述功能的模拟上是可行的。     

Tramadol, M1 metabolite and enantiomer affinities for cloned human opioid receptors expressed in transfected HN9.10 neuroblastoma cells

Tramadol hydrochloride is a centrally acting synthetic analgesic in widespread clinical use. Despite different degrees of opioid-like characteristics in preclinical tests, it is characterized by lack of full naloxone reversibility or naloxone-precipitated withdrawal in humans. To investigate this apparent discrepancy, the present study measured the affinity of tramadol (and its enantiomers) and an active O-desmethyl metabolite (M1) (and its enantiomers) to cloned human opioid receptors of the mu, delta and kappa type stably expressed in HN9.10 neuroblastoma cells. At mu sites, the Ki values for tramadol, its (+) and (-) enantiomers, M1, and its (+) and (-) enantiomers were 17000, 15700, 28800, 3190, 153 and 9680 nM, respectively, compared to 7.1 nM for morphine. These results are consistent with the suggestion of a non-opioid contribution to the clinical profile of tramadol.     

Ternary alloying study of MoSi2

Ternary alloying of MoSi₂ with adding a series of transition elements was investigated by X-ray diffraction (XRD), scanning electron microscopy, transmission electron microscopy (TEM), and energy dispersive spectroscopy (EDS). Iron, Co, Ni, Cr, V, Ti, and Nb were chosen as alloying elements according to the AB₂ structure map or the atomic size factor. The studied MoSi₂ base alloys were prepared by the arc melting process from high-purity metals. The EDS analysis showed that Fe, Co, and Ni have no solid solubility in as-cast MoSi₂, while Cr, V, Ti, and Nb exhibit limited solid solubilities, which were determined to be 1.4±0.7, 1.4±0.4, 0.4±0.1, and 0.8±0.1. Micro-structural characterization indicated that Mo-Si-M_VIII (M_VIII=Fe, Co, Ni) and Mo-Si-Cr alloys have a two-phase as-cast microstructure, i.e., MoSi₂ matrix and the second-phase FeSi₂, CoSi, NiSi₂, and CrSi₂, respectively. In as-cast Mo-Si-V, Mo-Si-Ti, and Mo-Si-Nb alloys, besides MoSi₂ and C40 phases, the third phases were observed, which have been identified to be (Mo, V)₅Si₃, TiSi₂, and (Mo, Nb)₅Si₃.     

凸轮机构基圆半径的确定方法及其分析

基圆半径的确定方法，除了用图解法和试算法外，还可用解析法和图解分析法求解。４种方法各有优缺点，设计时要根据具体情况选择。     

Permeation of Zidovudine and Probenecid from Oily Bases Containing Alcohols Through Rat Skin

Permeation of zidovudine (3'-azido-3'-deoxythymidine, AZT) and probenecid from oily bases containing an alcohol through rat skin was examined. Isopropyl myristate (IPM), as an oily vehicle, showed a penetration enhancing effect for AZT and probenecid. Ethanol, n-propanol, and n-butanol were used as additives in IPM and were examined for their own permeation and the enhancing effect on the permeation of AZT and probenecid. The skin permeation of AZT and probenecid from IPM was enhanced by addition of the alcohol in IPM. The degree of the enhancement was decreased with increasing lipophilicity of the alcohol used. me permeation rate of the drug from those systems was shown to be governed by penetration-enhancing effects of the oily base and alcohol, and the penetration of the alcohol itself through the skin.     

The Air is Always Cleaner on the Other Side: Race,Space, and Ambient Air Toxics Exposures in California

Abstract: Environmental justice advocates have recently focused attention on cumulative exposure in minority neighborhoods due to multiple sources of pollution. This article uses U.S. EPA's National Air Toxics Assessment (NATA) for 1996 to examine environmental inequality in California, a state that has been a recent innovator in environmental justice policy. We first estimate potential lifetime cancer risks from mobile and stationary sources. We then consider the distribution of these risks using both simple comparisons and a multivariate model in which we control for income, land use, and other explanatory factors, as well as spatial correlation. We find large racial disparities in California's “riskscape” as well as inequalities by other factors and suggest several implications for environmental and land use policy.     

内蒙古煤系高岭土作为FCC催化剂基质的研究

研究两种内蒙古煤系高岭土（1^＃、2^＃）的化学组成、晶体结构并与苏州高岭土进行了比较。对三种高岭土进行酸改性，利用BET、吡啶-TPD和微反测试分别研究改性前后高岭土的性能特点。并将内蒙古高岭土1^＃与苏州高岭土采用半合成方法合成了FCC催化剂，测定了其裂化活性。研究结果表明，内蒙古1^＃具有较良好的晶体结构和化学组成，经酸改性后比表面积大大增加，具有合适的孔径分布，裂化活性较好，可以取代苏州高岭土作为FCC催化剂的基质。