燃料电池用QCS键和层析硅胶膜的制备及其性能表征

以季铵化壳聚糖(QCS)和层析硅胶为原料,制备了不同硅胶含量的多孔膜。用傅里叶变换红外(FTIR)和扫描电镜(SEM)对多孔膜的结构和形貌进行表征。同时,考察了层析硅胶的用量对多孔膜的含水率(WU)、溶胀度(SR)、机械性能和电导率的影响。结果表明,随着层析硅胶含量的增加,多孔膜的含水率、溶胀度和电导率均升高,但机械性能下降。当层析硅胶的用量为40%时,多孔膜的含水率高达816%,但是膜的溶胀度仅为189%,拉伸强度为5.6MPa,断裂伸长率为4.2%;在测试温度为70℃时,不同层析硅胶含量多孔膜的电导率数值分布在2.4~3.9×10~(-2)S/cm的范围内,且随硅胶含量的增加而增加。     

发动机进气系统高通量富氧膜的研制

采用交联改性的方法对较低分子量的乙烯基硅橡胶进行了改性研究,制备了高通量的富氧膜,结合单因素实验法和Design-expert正交实验设计,考察了原料配比、交联反应时间、固化温度和固化时间等因素对富氧膜性能的影响,确定了最佳富氧性能膜的制备条件:原料配比4.3,反应时间2.15h,固化温度86.25℃,固化时间1.75h;获得了富氧浓度为28.68%,透气量为4696.33 barrer的富氧膜,该膜的富氧浓度与常规商品化膜相当,透气量为常规商品化膜的2~4倍,有应用于发动机富氧进气系统的前景。通过扫描电镜检测、机械性能检测等手段对复合膜进行了进一步表征。     

箱式电阻炉炉温均匀度的测量不确定度评定

电阻炉是利用电流使炉内电热元件或加热介质发热,从而对工件或物料加热的工业炉。炉温均匀度是在各测温点上测得的最高、最低实际温度分别与中心点实际温度之差,对炉温均匀度的测量不确定度进行评定,可以反映电阻炉在热稳定状态时炉内工作温度的均匀程度,是衡量电阻炉的质量好坏的重要依据。     

GPS测量系统误差分析

本文引出了GPS姿态测量,介绍了GPS测量原理,根据GPS测量系统的特点分析了测量过程中的各种误差,并提出了相应的误差消除措施。     

XF30A~*数字多用表校准仪电压、电流测量不确定度的分析与评定

XF30A*数字多用表校准仪是智能化交直、流标准电压、电流校准仪,具有数字显示、误差直读、量程宽、精度高、稳定性好、使用方便等特点,适用于检定、校准四位半数字三用表,各种0.2级、0.5级以下指针式交直流电压、电流表,作为企业计量室三用表检定、校准标准装置被广泛应用。     

光纤光栅形状传感器的研究

传感器总长810mm,直径为2.5mm,4根光纤布喇格光栅(fiber Bragg grating,FBG)互成90°分布在用记忆合金丝(Shap Memory Alloy,SMA)做基材的表面。通过在波分复用的基础上添加光时分复用来改进传感网络布置,提高测量精度;同时,设计了一套封装装置来确保封装时FBG与基材之间的准确定位以及黏结剂能够均匀的涂覆在基材和FBG表面,提高传感器的封装精度。实验结果表明,该FBG形状传感器的测量精度为3.1%。     

旋转摩擦挤压法制备CNTs/Mg复合材料的组织和力学性能

通过显微硬度和抗拉强度试验、X射线衍射仪、扫描电镜和金相显微镜观察,研究经旋转摩擦挤压法制备的CNTs/Mg复合材料的组织及性能。结果表明:CNTs/Mg复合材料的组织为细小等轴晶,且随着CNTs含量的增加,复合材料晶粒尺寸逐渐细化,当CNTs含量为5%时,晶粒尺寸最小,由63μm减小至3.79μm,为AZ91基材晶粒尺寸的6.01%。经过旋转摩擦挤压加工后基材内第二相β-Al12Mg17相的量减少,CNTs的加入使复合材料中出现了Al4C3相,且第二相β-Al12Mg17相网状结构消失。加工后的镁合金抗拉强度提高,最大值为330.9 MPa,较原基材提高了90.6%,当CNTs含量小于2%时,复合材料强度高于原基材。复合材料硬度随着CNTs含量的增加呈先增加后降低的趋势,当CNTs含量为2%时,硬度最高,达101.3HV,比AZ91基材提高了40.3%。     

泡沫铝三明治板的研究与应用进展

泡沫铝三明治板(Aluminum foam sandwich,AFS)是基于泡沫铝材料开发的一类材料-结构一体化的先进多孔复合结构。AFS是交通运输、建筑以及航空航天等装备结构轻量化的重要材料,具有广阔的应用前景。概述了AFS的几类制备技术的基本原理和研究现状,着重分析了复合预制体制备、合金成分、AFS发泡成型工艺等关键环节中存在的理论和技术难点。介绍了AFS作为结构材料和功能材料的典型应用案例;最后总结提出了AFS材料研究和工程化技术开发的关键点与突破途径。     

A smooth simultaneous confidence band for correlation curve

A plug-in estimator is proposed for a local measure of variance explained by regression, termed correlation curve in Doksum et al. (J Am Stat Assoc 89:571–582, 1994), consisting of a two-step spline–kernel estimator of the conditional variance function and local quadratic estimator of first derivative of the mean function. The estimator is oracally efficient in the sense that it is as efficient as an infeasible correlation estimator with the variance function known. As a consequence of the oracle efficiency, a smooth simultaneous confidence band (SCB) is constructed around the proposed correlation curve estimator and shown to be asymptotically correct. Simulated examples illustrate the versatility of the proposed oracle SCB which confirms the asymptotic theory. Application to a 1995 British Family Expenditure Survey data has found marginally significant evidence for a local version of Engel’s law, i.e., food budget share and household real income are inversely related (Hamilton in Am Econ Rev 91:619–630, 2001).     

PD‐1 Blockade for Improving the Antitumor Efficiency of Polymer–Doxorubicin Nanoprodrug

Chemotherapy is well recognized to induce immune responses during some chemotherapeutic drugs‐mediated tumor eradication. Here, a strategy involving blocking programmed cell death protein 1 (PD‐1) to enhance the chemotherapeutic effect of a doxorubicin nanoprodrug HA‐Psi‐DOX is proposed and the synergetic mechanism between them is further studied. The nanoprodrugs are fabricated by conjugating doxorubicin (DOX) to an anionic polymer hyaluronic acid (HA) via a tumor overexpressed matrix metalloproteinase sensitive peptide (CPLGLAGG) for tumor targeting and enzyme‐activated drug release. Once accumulated at the tumor site, the nanoprodrug can be activated to release antitumor drug by tumor overexpressed MMP‐2. It is found that HA‐Psi‐DOX nanoparticles can kill tumor cells effectively and initiate an antitumor immune response, leading to the upregulation of interferon‐γ. This cytokine promotes the expression of programmed cell death protein‐ligand 1 (PD‐L1) on tumor cells, which will cause immunosuppression after interacting with PD‐1 on the surface of lymphocytes. The results suggest that the therapeutic efficiency of HA‐Psi‐DOX nanoparticles is significantly improved when combined with checkpoint inhibitors anti‐PD‐1 antibody (α‐PD1) due to the neutralization of immunosuppression by blocking the interaction between PD‐L1 and PD‐1. This therapeutic system by combining chemotherapy and immunotherapy further increases the link between conventional tumor therapies and immunotherapy.