Enzyme-linked immunosorvent assay using vertical microreactor stack with microbeads

The advantages of vertical microreactor stack with three-dimensional (3D) structure for immunoassay are discussed. The vertical microreactor stack uses vertical fluid flow operation with multifunctional fluid filters. The multi function of fluid filter is very effective for micromixing and passive valve operation. The mechanism of micromixing is discussed by using computational fluid dynamics (CFD), and we know that the mixing mechanism based on Coanda effect. To evaluate the micromixing performance of fluid filter, we demonstrated enzyme reaction with unique repeat mixing operation. As the results, we proved that the fluid filter has very effective mixing performance. The detection limit, which demonstrated by competition enzyme-linked immunosorvent assay (ELISA), is comparable with recommended detection limit, which suggested by Japanese ministry for the environment.     

Additional kernel observer: privilege escalation attack prevention mechanism focusing on system call privilege changes

International Journal of Information Security - Cyberattacks, especially attacks that exploit operating system vulnerabilities, have been increasing in recent years. In particular, if administrator...     

Molar-Volume Dependence of the Pressure in hcp Solid 3He in Magnetic Fields

Pressure measurements have been made in a hcp solid ³ He at molar volumes from 18.90 to 19.45 cm ³ /mol, at temperatures down to 1 mK and in magnetic fields up to 0.16 Tesla. The results are analyzed by a high-temperature series expansion with multiple-exchange processes. The molar volume dependence of the multiple-exchange interactions has been determined by pressure measurements in magnetic fields. The results indicate that the exchange frequencies determined by the pressure measurements in a hcp solid ³ He are consistent with those obtained by magnetization measurements.     

Magnetic Torque Measurements on Bi2201 Single Crystal in High Magnetic Fields

The magnetic field direction dependence of the magnetic torque in the superconducting state of Bi ₂ Sr _1.65 La _0.35 CuO ₆₊ (Bi2201) single crystal has been measured in several static magnetic fields up to 200 kOe. The applied field dependence of the anisotropy parameter, , defined by the square root of the effective mass ratio has been obtained by fitting the magnetic torque curves at 17 K by means of the effective mass model. For Bi ₂ Sr ₂ CaCu ₂ O ₈₊ (Bi2212), the values up to 210 kOe were reported previously. At each field, for Bi2201 is larger than that for Bi2212. Since the value decreases as the field increases both for Bi2201 and Bi2212, the reduction of by the application of the high magnetic field is considered to be common for Bi-based layered superconductors.     

Grasp and Delivery for Moving Objects on Broken Lines

This paper studies the following variant of the Vehicle Routing Problem that we call the Grasp and Delivery for Moving Objects (GDMO) problem, motivated by robot navigation: The input to the problem consists of n products, each of which moves on a predefined path with a fixed constant speed, and a robot arm of capacity one. In each round, the robot arm grasps one product and then delivers it to the depot. The goal of the problem is to find a collection of tours such that the robot arm grasps and delivers as many products as possible. In this paper we prove the following results: (i) If the products move on broken lines with at least one bend, then the GDMO is MAXSNP-hard, and (ii) it can be approximated with ratio 2. However, (iii) if we impose the “straight line without bend” restriction on the motion of every product, then the GDMO becomes tractable. Y. Asahiro’s research was supported in part by Grant-in-Aid for Young Scientists 15700021, and Research on Priority Areas 16092223. E. Miyano’s research was supported in part by Grant-in-Aid for Research on Priority Areas 16092223. Presently, S. Shimoirisa is with the Software Development Engineering Department, Products Development Center, Retail Information Systems Company, Toshiba TEC Corporation.     

A 250-Mb/s/pin, 1-Gb double-data-rate SDRAM with a bidirectionaldelay and an interbank shared redundancy scheme

This paper describes three circuit technologies indispensable for high-bandwidth multibank DRAM's. (1) A clock generator based on a bidirectional delay (BDD) eliminates the output skew. The BDD measures the cycle time as the quantity charged or discharged of an analog quantity, and replicates it in the next cycle. This achieves a 0.18-mm ², two-cycle-lock clock generator operating from 25 to 167 MHz with a 30-ps resolution. (2) A quad-coupled receiver eliminates the internal skew caused by the difference between a rise input and a fall input by 40%. (3) An interbank shared redundancy scheme (ISR) with a variable unit redundancy (VUR) efficiently increases yield in multibank DRAM's. The ISR allows redundancy match circuits to be shared with two or more banks. The VUR allows the number of units replaced to be variable. These circuit technologies achieved a 250-Mb/s/pin, 8-bank, 1-Gb double-data-rate synchronous DRAM     

Quantum-confined field-effect light emitters: device physics andexperiments

Extended experimental results on three-terminal quantum-confined field-effect light emitters with current injection and field control of luminescent characteristics in the quantum-well structure are reported. By incorporating superlattice buffer layers (SLBLs), the quantum efficiency of the device is dramatically improved and equivalently nonradiative recombination processes are sufficiently suppressed at room temperature. The red-shift of the emission spectra by the quantum-confined Stark effect assures that the electric field is effectively applied to the quantum well. The experimental data on the transient responses of emission intensity to input voltage pulses show fairly good correspondences with theoretical prediction and previous photoluminescence experiments. The authors discuss the ultimate capability of high-speed switching and point that an optical pulse with a duration as short as 30 ps and involving more than 100 photons can be generated by scaling down the size of the device with 1% external efficiency