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排序方式: 共有585条查询结果,搜索用时 31 毫秒
21.
Zachary Finewax Demetrios Pagonis Megan S. Claflin Anne V. Handschy Wyatt L. Brown Olivia Jenks Benjamin A. Nault Douglas A. Day Brian M. Lerner Jose L. Jimenez Paul J. Ziemann Joost A. de Gouw 《Indoor air》2021,31(5):1323-1339
Humans spend approximately 90% of their time indoors, impacting their own air quality through occupancy and activities. Human VOC emissions indoors from exercise are still relatively uncertain, and questions remain about emissions from chlorine-based cleaners. To investigate these and other issues, the ATHLETic center study of Indoor Chemistry (ATHLETIC) campaign was conducted in the weight room of the Dal Ward Athletic Center at the University of Colorado Boulder. Using a Vocus Proton-Transfer-Reaction Time-of-Flight Mass Spectrometer (Vocus PTR-TOF), an Aerodyne Gas Chromatograph (GC), an Iodide-Chemical Ionization Time-of-Flight Mass Spectrometer (I-CIMS), and Picarro cavity ringdown spectrometers, we alternated measurements between the weight room and supply air, allowing for determination of VOC, NH3, H2O, and CO2 emission rates per person (emission factors). Human-derived emission factors were higher than previous studies of measuring indoor air quality in rooms with individuals at rest and correlated with increased CO2 emission factors. Emission factors from personal care products (PCPs) were consistent with previous studies and typically decreased throughout the day. In addition, N-chloraldimines were observed in the gas phase after the exercise equipment was cleaned with a dichlor solution. The chloraldimines likely originated from reactions of free amino acids with HOCl on gym surfaces. 相似文献
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D. Grant Willhite Jennifer R. Brigati Katie E. Selcer Joshua E. Denny Zachary A. Duck Stephen E. Wright 《Yeast (Chichester, England)》2014,31(9):361-374
Many fungi have evolved mechanisms to assess environmental nutrient availability prior to the energy‐intensive process of mating. In this study, we examined one such system in Saccharomyces cerevisiae, involving a glucose‐sensing pathway mediated by Gpr1p and the pheromone‐induced mating pathway. Initially we observed that the mating pathway in MATa cells is sensitive to environmental glucose depletion. This phenomenon can be partially reversed with a high glucose spike, but not with the addition of low levels of glucose. Deletion of the low‐affinity glucose receptor, Gpr1p, eliminated this glucose‐induced recovery of pheromone responsiveness. We then determined the impact of GPR1 deletion on the mating pathway and observed that, in all end points studied, the mating pathway response to pheromone is reduced in the absence of Gpr1p. Similarly, elimination of the Gα for Gpr1p, Gpa2p, resulted in reduction in pheromone sensitivity in all assays studied. The negative effect of removing Gpr1p on mating pathway activation could be recovered by overexpressing the mating receptor, Ste2p. Furthermore, Ste2p levels are reduced in the absence of glucose and GPR1. These data suggest that activity of the GPCR‐mediated mating pathway in S. cerevisiae is modulated by extracellular glucose concentrations through the only other GPCR in MATa cells, Gpr1p. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
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Zachary Freudenburg Khaterah Kohneshin Erik Aarnoutse Mariska Vansteensel Mariana Branco Sacha Leinders Max van den Boom Elmar G. M. Pels Nick Ramsey 《控制理论与应用(英文版)》2021,19(4):444-454
While brain computer interfaces (BCIs) offer the potential of allowing those suffering from loss of muscle control to once
again fully engage with their environment by bypassing the affected motor system and decoding user intentions directly from
brain activity, they are prone to errors. One possible avenue for BCI performance improvement is to detect when the BCI user
perceives the BCI to have made an unintended action and thus take corrective actions. Error-related potentials (ErrPs) are
neural correlates of error awareness and as such can provide an indication of when a BCI system is not performing according
to the user’s intentions. Here, we investigate the brain signals of an implanted BCI user suffering from locked-in syndrome
(LIS) due to late-stage ALS that prevents her from being able to speak or move but not from using her BCI at home on a
daily basis to communicate, for the presence of error-related signals. We first establish the presence of an ErrP originating
from the dorsolateral pre-frontal cortex (dLPFC) in response to errors made during a discrete feedback task that mimics the
click-based spelling software she uses to communicate. Then, we show that this ErrP can also be elicited by cursor movement
errors in a continuous BCI cursor control task. This work represents a first step toward detecting ErrPs during the daily
home use of a communications BCI. 相似文献
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Autonomous Robots - Dynamic games are an effective paradigm for dealing with the control of multiple interacting actors. This paper introduces augmented Lagrangian GAME-theoretic solver (ALGAMES),... 相似文献
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Joseph R. Carazzone Christophe L. Martin Zachary C. Cordero 《Journal of the American Ceramic Society》2020,103(9):4754-4773
Cracking during sintering is a common problem in powder processing and is usually caused by constraint that prevents the sintering material from shrinking in one or more directions. Different factors influence sintering-induced cracking, including temperature schedule, packing density, and specimen geometry. Here we use the discrete element method to directly observe the stress distribution and sinter-cracking behavior in edge notched panels sintered under a uniaxial restraint. This geometry allows an easy comparison with traditional fracture mechanics parameters, facilitating analysis of sinter-cracking behavior. We find that cracking caused by self-stress during sintering resembles the growth of creep cracks in fully dense materials. By deriving the constrained densification rate from the appropriate constitutive equations, we discover that linear shrinkage transverse to the loading axis is accelerated by a contribution from the effective Poisson's ratio of a sintering solid. Simulation of different notch geometries and initial relative densities reveals conditions that favor densification and minimize crack growth, alluding to design methods for avoiding cracking in actual sintering processes. We combine the far-field stress and crack length to compute the net section stress, finding that it characterizes the stress profile between the notches and correlates with the sinter-crack growth rate, demonstrating its potential to quantitatively describe sinter-cracking. 相似文献
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Shermane Benjamin Silvina Pagola Zachary Huba Everett Carpenter Tarek Abdel-Fattah 《Synthetic Metals》2011,161(11-12):996-1000
This work describes the synthesis of the green and black polymorphic forms of the tetrathiafulvalene–chloranil (TTF–CA) charge transfer salt as pure phases, by solvent-assisted mechanochemistry. Both materials were characterized using laboratory and high-resolution X-ray powder diffraction (XRPD), elemental analysis and scanning electron microscopy (SEM). The high-resolution XRPD pattern of the TTF–CA black polymorph was indexed with a triclinic lattice a = 10.756(5) Å, b = 11.057(4) Å, c = 6.614(2) Å, α = 101.36(2)°, β = 93.69(3)°, γ = 89.37(3)°, V = 769.6(5) Å3. The chemical stability of these phases upon heating was investigated using thermogravimetric analysis (TGA), elemental analysis and X-ray powder diffraction (XRPD), indicating that both polymorphs undergo chemical decomposition, and ruling out the transition to an air-stable high temperature polymorph. 相似文献