±800kV特高压换流变压器CAFS自动控制系统设计研究

固定式压缩空气泡沫灭火系统(CAFS)不仅具有灭火能力强、速度快、灭火效率高、安全可靠等特点,且经过试验验证,可用于扑救换流变压器等油类火灾.将其首次应用到国内某±800 kV换流站工程,阐述了压缩空气泡沫系统控制系统的结构、配置和功能,给出了站内设备布置和火灾报警系统接口等设计要点.对后续特高压工程压缩空气泡沫灭火控制系统设计具有借鉴作用.     

220 kV金属氧化物避雷器故障类型分析与处理

对近年上海220 kV金属氧化物避雷器故障进行分析,介绍了避雷器在线监测仪指针卡涩引起示数偏大、避雷器表面脏污或内部受潮等引起发热的问题,针对不同故障现象列举了带电检测和停电试验等故障诊断方法,并总结了故障诊断过程中的注意事项,以保证人身及设备安全.     

电池供电智能化电力产品的低功耗设计

电池供电的产品需要考虑低功耗设计.低功耗产品的设计,除了在产品的初始设计阶段考虑低功耗器件的选型、电源的设计等,还需要在设计过程中,结合软件及硬件的共同作用,来满足产品设计需要的低功耗设计.因此,对MCU三种主频选择、AD采集对象的供电电源切换以及无线通信空中速率的提高对功率影响变化进行介绍.由试验数据得出,调整外部设备运行方式可以降低功耗,在外部设备运行方式确定后,最低功率由调整MCU主频引起的功率变化与外围设备功率消耗的平衡相交点得出.通过试验设计来达到最佳的功率控制,延长了电池使用寿命.     

醇溶性疏水交联型丙烯酸酯环保胶黏剂的制备与表征

以乙醇为溶剂,N,N'-亚甲基双丙烯酰胺为交联单体,丙烯酸十八酯为长链疏水单体,通过溶液聚合制备了一种丙烯酸酯环保胶黏剂.通过1HNMR,FTIR,GPC,SEM,TGA等对聚合物的结构和性能进行表征与测试.研究了反应时间、反应温度、交联单体和疏水单体的用量以及硬软单体物质的量比对聚合物和膜性能的影响.结果表明,当反应时间为4 h,反应温度为80℃,交联单体含量为1％(占单体总质量,下同),硬软单体物质的量比为2:1时,聚合物重均相对分子质量为1.286×105,热分解温度为309.3℃,玻璃化转变温度为85.2℃,胶膜硬度达到4H.疏水单体的加入提高了聚合物膜的拉伸强度和疏水性能,与没加疏水单体相比,加入3％疏水单体后,胶膜的拉伸强度提高了184.2％,达到0.79 MPa;水接触角提高219.5％,达到78.6°.制备的环保型胶黏剂可用于含沙土壤的固化以及沙画、沙瓶画和浮雕画的固定等.     

轮胎炼胶生产能源管理系统

研究烷基二硫代磷酸锌TPZ在丁苯橡胶（SBR）/白炭黑体系中的应用。结果表明：在SBR/白炭黑体系中以TPZ等量替代促进剂DPG,TPZ具有类似促进剂DPG的活化作用,可降低胶料的滚动阻力,且更加环保;少量TPZ作为偶联活化剂用于SBR/白炭黑体系的母炼中,可以减小硅烷偶联剂用量,降低成本,提高填料分散性和偶联效率,从而使胶料获得更佳的物理性能和动态力学性能。     

Soluble Prokaryotic Overexpression and Purification of Human GM-CSF Using the Protein Disulfide Isomerase b′a′ Domain

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a member of the colony-stimulating factor (CSF) family, which functions to enhance the proliferation and differentiation of hematopoietic stem cells and other hematopoietic lineages such as neutrophils, dendritic cells, or macrophages. These proteins have thus generated considerable interest in clinical therapy research. A current obstacle to the prokaryotic production of human GM-CSF (hGM-CSF) is its low solubility when overexpressed and subsequent complex refolding processes. In our present study, the solubility of hGM-CSF was examined when combined with three N-terminal fusion tags in five E. coli strains at three different expression temperatures. In the five E. coli strains BL21 (DE3), ClearColi BL21 (DE3), LOBSTR, SHuffle T7 and Origami2 (DE3), the hexahistidine-tagged hGM-CSF showed the best expression but was insoluble in all cases at each examined temperature. Tagging with the maltose-binding protein (MBP) and the b′a′ domain of protein disulfide isomerase (PDIb′a′) greatly improved the soluble overexpression of hGM-CSF at 30 °C and 18 °C. The solubility was not improved using the Origami2 (DE3) and SHuffle T7 strains that have been engineered for disulfide bond formation. Two conventional chromatographic steps were used to purify hGM-CSF from the overexpressed PDIb′a′-hGM-CSF produced in ClearColi BL21 (DE3). In the experiment, 0.65 mg of hGM-CSF was isolated from a 0.5 L flask culture of these E. coli and showed a 98% purity by SDS-PAGE analysis and silver staining. The bioactivity of this purified hGM-CSF was measured at an EC₅₀ of 16.4 ± 2 pM by a CCK8 assay in TF-1 human erythroleukemia cells.     

Natural Polysaccharides as Multifunctional Components for One-Step 3D Printing Tough Hydrogels

Natural polysaccharides (NPS) are regarded as biomolecular and structural components for preparing high-performance tough hydrogels. But the one-step fabrication of NPS-containing hydrogels in seconds and the template-free design of complicated high-resolution structures are still significant challenges in this field. To meet these requirements, various NPS-containing tough hydrogels are fabricated and processed into 2D/3D structures via the combination of Ru(bpy)₃²⁺-mediated photochemistry and extrusion 3D printing technique. The whole fabrication process is one-step, completed in tens of seconds under visible light irradiation. It is found that the used NPS plays a key role in achieving the fabrication of high-performance structured tough hydrogels. The high reactivity of functional groups in the used NPS can shorten their gelation times. Long rigid chains of the used NPS, their hierarchical assemblies, and contrasting multinetworks benefit from the efficient dissipation of mechanical energy and enhancement of its operational stability. Strong supramolecular interactions enable hydrogel precursors to have high viscosities, therefore providing good controllability to design high-resolution and complicated tough hydrogel structures via extrusion 3D printing. It is anticipated that this straightforward fabrication strategy and findings will open new horizons for NPS-containing materials.     

Preparation and Bioactivity of Iridium(III) Phenanthroline Complexes with Halide Ions and Pyridine Leaving Groups

A series of half-sandwich structural iridium(III) phenanthroline (Phen) complexes with halide ions (Cl⁻, Br⁻, I⁻) and pyridine leaving groups ([(η⁵-Cp^X)Ir(Phen)Z](PF₆)_n, Cp^x: electron-rich cyclopentadienyl group, Z: leaving group) have been prepared. Target complexes, especially the Cp^xbiph (biphenyl-substituted cyclopentadienyl)-based one, showed favourable anticancer activity against human lung cancer (A549) cells; the best one ( Ir8 ) was almost five times that of cisplatin under the same conditions. Compared with complexes involving halide ion leaving groups, the pyridine-based one did not display hydrolysis but effectively caused lysosomal damage, leading to accumulation in the cytosol, inducing an increase in the level of intracellular reactive oxygen species and apoptosis; this indicated an anticancer mechanism of oxidation. Additionally, these complexes could bind to serum albumin through a static quenching mechanism. The data highlight the potential value of half-sandwich iridium(III) phenanthroline complexes as anticancer drugs.     

不同品质粉煤灰混凝土的微观力学性能研究

系统研究了I级粉煤灰、III级粉煤灰和等外粉煤灰对混凝土抗压强度和自收缩的影响,并采用纳米划痕仪重点分析了不同品质粉煤灰混凝土的微观力学性能.结果表明:III级粉煤灰和等外粉煤灰均明显降低混凝土的早期和后期抗压强度,且随着掺量的增加而下降,而I级粉煤灰能明显提高混凝土的后期强度,且随着掺量的增加而增加.I级粉煤灰、III级粉煤灰和等外粉煤灰均能明显降低混凝土的自收缩,且等外粉煤灰降低效果最好.在微观力学性能方面,I级粉煤灰与水泥基体界面区结构显著优于III级粉煤灰和等外粉煤灰,且界面区微观力学性能明显高于III级粉煤灰和等外粉煤灰.     

高镍三元正极材料表面碱性物质研究进展

高镍三元正极材料表面形成的碱性物质容易导致电池容量衰减加快、寿命缩短,因而调控三元材料表面碱性物质对于提高锂离子二次电池的功能和安全性至关重要。综述了高镍锂离子电池三元正极材料表面碱性物质的形成机理及处理手段,从不同角度阐述了环境中的水、二氧化碳对表面碱性物质形成的影响。探讨了表面碱性物质形成过程中,由于锂离子和过渡金属的迁移与固化引发的表面结构的相变现象,造成了三元正极材料的加工储存性能的恶化。还对降碱工艺中的洗涤、干燥、低温烧结等过程进行了重点说明,阐述了洗涤工艺对三元材料表面碱性物质降低及对材料性质的影响,指出需选择合适的洗涤、干燥条件,减小材料表面发生的变异。最后结合目前降碱工艺对后续研究方向提出了建议。