A Bio-inspired Method for Distributed Deployment of Services

We look at the well-known problem of allocating software components to compute resources (nodes) in a network, given resource constraints on the infrastructure and the quality of service requirements of the components to be allocated to nodes. This problem has many twists and angles, and has been studied extensively in the literature. Solving it is particularly problematic when there is extensive dynamism and scale involved. Typically, heuristics are needed.     

Direct photonic production: towards high speed additive manufacturing of individualized goods

World market competition currently boosts trends like mass customization and open innovation which result in a demand for highly individualized products at costs matching or beating those of mass production. This work focus on the resolution of the production related dilemma between scale and scope, e.g. either the low-cost production of high quantities or the high-end and thus cost-intensive low-volume production of individualized goods. One of the areas of greatest potential for the resolution of this dilemma are rapid manufacturing (RM) technologies due to their almost infinite geometrical variability and freedom of design without the need for part-specific tooling. Selective Laser Melting (SLM) is one of the RM technologies that additionally provides series identical mechanical properties without the need for downstream sintering processes, etc. However, the state-of-the-art process and cost efficiency is not yet suited for series production. In order to improve this efficiency and enable SLM to enter series production it is indispensable to increase the build rate significantly by means of increased laser power and larger beam diameters. To exploit this potential, a new generation production machine including a kW laser and an optical multi-beam system is developed and experimental results and real life components are shown.     

Anti-plane stress state of a plate with a V-notch for a new class of elastic solids

The main purpose of this study is to investigate the efficacy and usefulness of a class of recently proposed models that could be reasonable candidates for describing the response of brittle elastic materials. The class of models that are considered allows for a non-linear relationship between the linearized elastic strain and the Cauchy stress, and this allows one to describe situations wherein the stress increases while the strain yet remains small. Thus one would be in a position to model the response of brittle elastic bodies in the neighborhood of the tips of cracks and notches. In this paper we study the behavior of such models in a plate with a V-notch subject to a state of anti-plane stress. This geometrical simplification enables us to characterize the governing equation for the problem by means of the Airy stress function, though the constitutive relation is a non-linear relation between the linearized strain and the stress. We study the problem numerically by appealing to the finite element method. We find that the numerical solutions are stable. We are able to provide some information regarding the nature of the solution near the tip of the V-notch. In particular we find stress concentration in the vicinity of the singularity.     

A formulation to model the nonlinear viscoelastic properties of the vascular tissue

Nearly all soft tissues, including the vascular tissue, present a certain degree of viscoelastic material response, which becomes apparent performing multiple relaxation tests over a wide range of strain levels and plotting the resulting stress relaxation curves, nonlinear viscoelasticity of the tissue. Changes in relaxation rate at each strain may occur at multiple strain levels. A constitutive formulation considering the particular features of the vascular tissue, such as anisotropy, together with these nonlinear viscoelastic phenomena is here presented and used to fit stress?Cstretch curves from experimental relaxation tests. This constitutive model was used to fit several data set of in vitro experimental stress relaxation tests performed on ovine and porcine aorta. The good fitting of the experimental data shows the capability of the model to reproduce the viscoelastic response of the vascular tissue.     

Native and Biotechnologically Engineered Plant Proteases with Industrial Applications

Proteases occupy the most relevant position among industrial enzymes. Plant proteases have been used in medicine, detergent manufacturing, and food science for many years, but their production is diminishing in favor of those of microbial origin because lower production costs. Papain, bromelain, and ficin are the most frequently employed plant proteases, although new proteases with new and more appealing physicochemical properties for industry are still emerging. DNA technology and genetic engineering shall play, without a doubt, an important role for the production of these proteases at the industrial level. The present review focuses on the applications of traditional plant proteases as well as new proteases discovered during the last 20 years, some of which have already been genetically engineered either to increase production or to strengthen some of their physicochemical properties. The review also refers to the protease classification, action pattern, and main characteristics.     

The Influence of Oxygen Volumetric Mass Transfer Rates on Cyclodextrin Glycosyltransferase Production by Alkaliphilic Bacillus circulans in Batch and Fed-Batch Cultivations

In this work, the influence of oxygen mass transfer rates on the production of cyclodextrin glycosyltransferase (CGTase) by the alkaliphilic bacterium Bacillus circulans ATCC 21783 was investigated. Experimental design and response surface methodology were applied to optimize agitation speed and air flow rate in batch cultivations, in order to identify their significant effects and interactions with the synthesis of CGTase. Results were expressed as the volumetric mass transfer rates of oxygen (k_la, [per hour]). The maximal CGTase productivity of 155 U mL⁻¹ h⁻¹ was achieved with k_la of 48 h⁻¹. CGTase production was also studied in fed-batch cultures using the optimized parameters obtained in the batch experiments. The maximal CGTase productivity on fed-batch cultivations was 137 U mL⁻¹ h⁻¹ with feeding rates of starch at 0.17 g L⁻¹ h⁻¹.     

Stability of some stationary solutions to the forced KdV equation with one or two bumps

Free-surface flows past submerged obstacles in a channel are considered. The fluid is assumed to be inviscid and incompressible and the flow to be irrotational. The first-order approximation of long nonlinear surface waves over one or two bumps results in a forced Korteweg?Cde Vries (fKdV) equation. Solutions of the stationary fKdV equation are constructed and their stability is studied, either analytically or numerically. These various solutions include solitary waves over a single bump, solitary waves with two humps over a double bump, table-top solutions over a double bump and fronts.     

Characterization of MEMS Devices for the Study of?Superfluid Helium Films

Measurements on the mechanical properties of MEMS resonators were performed to characterize such devices at room temperature and low temperatures. Using state-of-the-art silicon integrated circuit technology, we have designed, fabricated, and manufactured resonators consisting of a pair of parallel plates with a well-defined gap whose size can be controlled with a high accuracy down to the sub-micron range. A full study of resonance properties at various pressures was performed at room temperature. We will discuss the details of design, fabrication, and operation. These studies open up a window of opportunities to look for novel phenomena in quantum fluids such as in superfluid ³He films.