全文获取类型
收费全文 | 566796篇 |
免费 | 6228篇 |
国内免费 | 1004篇 |
专业分类
电工技术 | 10508篇 |
综合类 | 466篇 |
化学工业 | 90045篇 |
金属工艺 | 23335篇 |
机械仪表 | 18498篇 |
建筑科学 | 12536篇 |
矿业工程 | 4312篇 |
能源动力 | 14429篇 |
轻工业 | 45758篇 |
水利工程 | 6941篇 |
石油天然气 | 14961篇 |
武器工业 | 39篇 |
无线电 | 60297篇 |
一般工业技术 | 116220篇 |
冶金工业 | 95564篇 |
原子能技术 | 14683篇 |
自动化技术 | 45436篇 |
出版年
2021年 | 5482篇 |
2019年 | 5268篇 |
2018年 | 9205篇 |
2017年 | 9410篇 |
2016年 | 9833篇 |
2015年 | 6026篇 |
2014年 | 10245篇 |
2013年 | 26108篇 |
2012年 | 15775篇 |
2011年 | 21090篇 |
2010年 | 16972篇 |
2009年 | 18821篇 |
2008年 | 19068篇 |
2007年 | 18771篇 |
2006年 | 16287篇 |
2005年 | 14743篇 |
2004年 | 14008篇 |
2003年 | 13691篇 |
2002年 | 13247篇 |
2001年 | 12852篇 |
2000年 | 12329篇 |
1999年 | 12011篇 |
1998年 | 27649篇 |
1997年 | 20041篇 |
1996年 | 15628篇 |
1995年 | 12006篇 |
1994年 | 10859篇 |
1993年 | 10612篇 |
1992年 | 8332篇 |
1991年 | 8102篇 |
1990年 | 7991篇 |
1989年 | 7763篇 |
1988年 | 7478篇 |
1987年 | 6748篇 |
1986年 | 6534篇 |
1985年 | 7390篇 |
1984年 | 6700篇 |
1983年 | 6438篇 |
1982年 | 5776篇 |
1981年 | 5896篇 |
1980年 | 5630篇 |
1979年 | 5733篇 |
1978年 | 5663篇 |
1977年 | 6178篇 |
1976年 | 7687篇 |
1975年 | 5108篇 |
1974年 | 4904篇 |
1973年 | 4980篇 |
1972年 | 4279篇 |
1971年 | 4038篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Using high-NA step index optical fibers, we show, theoretically, that large-bandwidth second-harmonic generation and sum frequency generation can be achieved at conversion frequencies in the visible region of the spectrum 相似文献
992.
J Berciano J Figols A García E Calle I Illa M Lafarga MT Berciano 《Canadian Metallurgical Quarterly》1997,20(7):846-857
The pathological basis of nerve inexcitability in Guillain-Barré syndrome has not been established with certainty. We report the clinicopathological findings in a 67-year-old patient with fulminant Guillain-Barré syndrome who died 18 days after onset. Three serial electrophysiological studies revealed nerve inexcitability. Antibodies to Campylobacter jejuni were present but there was no antiganglioside reactivity. Spinal root sections revealed extensive and almost pure macrophage-associated demyelination with occasional presence of T lymphocytes and neutrophil leukocytes. Conversely, in femoral, median, and sural nerves the outstanding lesion was axonal degeneration, with some denuded axons remaining. Unmyelinated fibers, posterior root ganglia, and dorsal columns were preserved. Endoneurial postcapillary venules showed plump endothelial cells with loss of their tight junctions. We conclude that both primary demyelination and axonal degeneration secondary to inflammation account for nerve inexcitability. Our findings lend support to the hypothesis of increased endoneurial pressure as the cause of wallerian degeneration in nerve trunks. 相似文献
993.
F van Rhee RM Szydlo J Hermans A Devergie F Frassoni W Arcese T de Witte HJ Kolb D Niederwiser N Jacobsen G Gahrton G Bandini E Carreras A Bacigalupo M Michallet T Ruutu J Reiffers JM Goldman J Apperley A Gratwohl 《Canadian Metallurgical Quarterly》1997,20(7):553-560
The purpose of this study was to determine the long-term results of allogeneic bone marrow transplantation for chronic myeloid leukemia. A retrospective analysis was carried out of the outcome of 373 consecutive transplants performed at 38 European institutions between 1980 and 1988 and reported to the registry of the European Group for Blood and Marrow Transplantation. All transplants were carried out for first chronic phase of chronic myelogenous leukemia using unmanipulated marow cells from HLA-identical sibling donors. The probability of survival and leukemia-free survival at 8 years were 54% (95% CI: 49-59) and 47% (95% CI: 41-52) respectively. The probabilities of developing acute GVHD (II-IV) at 100 days and chronic GVHD at 4 years after transplant were 47% (95% CI: 41-53) and 52% (95% CI: 46-58) respectively. The probabilities of transplant-related mortality and leukemic relapse 8 years after BMT were 41% (95% CI: 36-48) and 19% (95% CI: 14-25), respectively. Transplant within 12 months of diagnosis was associated with reduced transplant-related mortality (34 vs 45%, P = 0.013) and resulted in improved leukemia-free survival (52 vs 44%, P = 0.03). The probability of relapse was significantly reduced in patients who developed chronic GVHD (RR = 0.33, P = 0.004). The probability of relapse occurring more than 2 years after transplant was increased more than five-fold in patients transplanted from a male donor (RR = 5.5, P = 0.006). Sixty-seven patients in hematologic remission were studied for residual disease by two-step RT/PCR for BCR-ABL mRNA and 61 (91%) tested negative. We conclude that bone marrow transplantation can induce long-term survival in approximately one-half of CML patients; the majority of survivors have no evidence of residual leukemia cells when studied by molecular techniques. The probability of late relapse is increased with use of a male donor. 相似文献
994.
F F?ndrich AM Waaga J Schr?der E Schweizer A Schmid S Jacob HH Wacker P Schroeder 《Canadian Metallurgical Quarterly》1995,27(2):1553-1554
995.
J. A. Dain 《Computer Languages, Systems and Structures》1994,20(4):239-252
We present a method for recovering from syntax errors encountered during parsing. The method provides a form of minimum distance repair, has linear time complexity, and is completely automatic. A formal method is presented for evaluating the performance of error recovery methods, based on global minimum-distance error correction. The minimum-distance error recovery method achieves a theoretically best performance on 80% of Pascal programs in the weighted Ripley-Druseikis collection. Comparisons of performance with other error recovery methods are given. 相似文献
996.
We have previously shown that strychnine mimics the cytoprotective properties of glycine in renal proximal tubule (RPT) suspensions exposed to antimycin A (AA). The aims of this study were to determine whether the cytoprotective properties of strychnine applied to various types of nephrotoxicants and to examine the temporal aspects of the cytoprotection of glycine and strychnine. Tubular release of LDH activity was used as a marker of cell death. Glycine (2 mM) or strychnine (1 mM) added 5 min prior to the toxicant decreased LDH release in rabbit RPT suspensions exposed to 25 microM tetrafluoroethyl-L-cysteine (TFEC), 10 microM HgCl2, 0.5 mM t-butyl hydroperoxide (TBHP), or 0.2 mM bromohydroquinone (BHQ) for 4 hr, or 2 mM sodium cyanide (NaCN) for 2 hr. The relative rank order of effectiveness of glycine and strychnine was NaCN = TFEC > BHQ > DCVC > TBHP > HgCl2. The temporal aspects of strychnine and glycine protection were examined by exposing RPT to either AA or TFEC for 1 or 3 hr, respectively, and then adding either 1 mM glycine or 1 mM strychnine. Glycine and strychnine decreased LDH release in AA-treated RPT at 1.25 and 2 hr and TFEC-treated RPT at 4 hr. In addition, when RPT exposed to AA or TFEC and treated with strychnine or glycine were washed at either 1 or 4 hr, protection was eliminated at later time points. When glycine was added to RPT treated with either PCBC, TFEC, or DCVC 5 min prior to or 30, 60, 120, and 180 min following toxicant addition, LDH release was reduced at all time points. These results demonstrate that strychnine and glycine protect RPT from a variety of diverse nephrotoxicants, strychnine and glycine do not need to be present at the time of toxic insult, strychnine and glycine cytoprotection is reversible, and strychnine and glycine act in the late phase of necrotic cell injury. 相似文献
997.
998.
A Burger D Voges P Demange CR Perez R Huber R Berendes 《Canadian Metallurgical Quarterly》1994,237(4):479-499
Annexin V binds to phospholipids in a calcium-dependent manner and exhibits calcium channel activity in vitro. We prepared a variety of mutants yielding information about the structure-function relationship of the ion channel activity. All mutants were characterized by X-ray crystallography, electron microscopy and electrophysiological measurements. Their structures are insignificantly changed whereas their electrophysiological properties are drastically different. Glu95, located in the central hydrophilic pore of the molecule, is crucial for the ion selectivity filter as its exchange leads to reduced calcium and increased sodium conductance. The removal of Glu17, located on the protein surface and far from the ion conduction pathway, leads to the appearance of a second conductance level of 9 pS in addition to the conductance level of about 30 pS in the wild-type molecule. This was also the case for Glu78, which is part of a weak calcium binding site. The exchange of Glu17 and Glu78 produced a mutant retaining only the smaller conductance level. We conclude that these two residues influence the angle between the two halves of the molecule, which determines the diameter of the ion conduction pathway, thereby leading to the occurrence of a second conductance level. 相似文献
999.
1000.
The management of innovation inevitably implies the management of uncertainty. Research and practise clearly indicate that judgements about the size and the nature of this are often inaccurate. This can result in poor performance against expectations and in some cases in complete failure. In this paper it is argued that prior analysis of the type of uncertainty can help to improve the success rate and/or reduce the time to completion. Early signs that discontinuation, or a significant change in direction, might be called for are also highlighted by this analysis. 相似文献