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101.
102.
The clinical, radiologic, and histopathologic features of two main disorders of the orbit are discussed. Group I, Langerhans cell histiocytosis (histiocytosis X, Class I), is caused by proliferation of X histiocytic Langerhans' cells. Group II is juvenile xanthogranuloma, and Class II is related to the proliferation of non-X histiocytic (monocyte-macrophage) cells. The two diseases are of unknown cause and differ in their clinical, radiologic, and histopathologic features. 相似文献
103.
104.
KJ Barakat K Cheng WW Chan BS Butler TM Jacks KD Schleim DF Hora GJ Hickey RG Smith AA Patchett RP Nargund 《Canadian Metallurgical Quarterly》1998,8(11):1431-1436
A new class of potent, orally active phenyl piperazine-based GH secretagogues have been discovered from attempts to mimic the arrangement of the phenyl substituent in the spiroindanyl piperidine and spiroindoline sulfonamide privileged structures of 4 and 1, respectively. The best of these compounds, 18 (EC50 = 2.8 nM) is nearly as potent as MK-0677 for releasing GH from rat pituitary cells. 相似文献
105.
AC Buenafe H Offner M Machnicki H Elerding K Adlard R Jacobs AA Vandenbark G Adamus 《Canadian Metallurgical Quarterly》1998,161(4):2052-2059
T cells infiltrating the iris/ciliary body of Lewis rats with anterior uveitis (AU) that had been induced by myelin basic protein (MBP) immunization were previously found to share surface markers common to the T cells that cause experimental autoimmune encephalomyelitis (EAE). To determine whether these AU-associated T cells are in fact the same as those that infiltrate the central nervous system to cause EAE, we examined TCR V gene expression in T cells infiltrating the anterior chamber in rats with AU. As with EAE, we found a biased expression of Vbeta8.2 and Valpha2 in the iris/ciliary body and, although one would expect an influx of nonspecific inflammatory T cells, these biases were still evident at the peak of AU. An analysis of the TCR Vbeta8.2 and Valpha2 sequences derived from the iris/ciliary body demonstrated the presence of the same complementarity determining region 3 motifs found in MBP-specific T cells that are pathogenic for EAE and found in T cells derived from the central nervous system of rats with EAE. Finally, T cells isolated from the iris/ciliary body of rats with AU were found to proliferate in a specific fashion to MBP Ags. Thus, it appears that MBP-specific T cells are pathogenic for AU as well as EAE in the Lewis rat. In addition, the long-term presence of this highly restricted MBP response in the iris/ciliary body indicates that distinct immunoregulatory mechanisms exist in the environment of the eye. This provides an interesting model with which to address questions pertaining to the nature of T cells infiltrating the eye and their regulation during EAE and other systemic diseases. 相似文献
106.
AA Skolnick 《Canadian Metallurgical Quarterly》1998,279(11):816-817
107.
108.
AA Gubareva 《Canadian Metallurgical Quarterly》1998,(6):141-143
Systemic enzymes (wobenzime and wobe-mugos) were approved, that had been prescribed as part of polychemotherapy to 24 patients with malignant lymphomas, who presented with large masses of lymphatic nodes poorly resorbable against the background of polychemotherapy and who were assigned for a high-total dose irradiation, which fact would undoubtedly entail sclerosing of adjacent intact tissues. The use of the enzymes made for the optimum realization of the polychemotherapy effect and permitted avoiding a good many of undesirable side events and complication thereof. The above systemic enzymes are well tolerated by patients; they induce no significant changes in the cellular composition or in blood biochemical indices. 相似文献
109.
Kalugin R. N. Anokhov A. E. Fedina I. V. 《Power Technology and Engineering (formerly Hydrotechnical Construction)》2021,55(2):256-262
Power Technology and Engineering - The results of complex studies of welded joints made of steel P91 (X10CrMoVNb9-1) with repair welding performed in OAO VTI are presented. A control weld joint was... 相似文献
110.
Gaodu A. N. Subochev I. G. Pitak N. V. Yuzvuk D. I. Kalugin G. A. Kislitsin V. M. Kovylov V. M. 《Refractories and Industrial Ceramics》1975,16(7-8):477-478
Refractories and Industrial Ceramics - The feasibility was demonstrated of producing refractory fiber from high-alumina chamotte of calcined Arkalyk clay. The fiber properties conform to the... 相似文献