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91.
There is increasing interest in distinguishing the effects of physical and psychosocial workplace stressors on the aetiology of work-related musculoskeletal disorders (MSD). Modest associations have been found between psychosocial stressors and MSD, such as intensive load, monotonous work and low job control. Interpretation of these results has been limited by likely covariation between physical and psychosocial stressors. This investigation examined exposure covariation among blue- and white-collar workers employed in a mass production manufacturing environment (N = 410). Physical stressors were assessed from questionnaire and accelerometry. Psychosocial stressors were assessed from questionnaire. Pearson and Spearman correlation coefficients were computed. An exploratory factor analysis procedure identified possible common factors linking specific physical and psychosocial stressors. Moderate to high correlations between some physical and psychosocial stressors showed evidence of covariation both across and within groups. Covariation was strongest among blue-collar production and low-status office workers. Factor analysis results showed considerable shared variance between some physical and psychosocial stressors, such as repetition and job control, suggesting that these disparate stressors manifest from common work organization factors that govern the structure of work. While recognizing the conceptual differences between physical and psychosocial stressors, these results call attention to the strong empirical relationships that can exist between some stressors in the workplace setting. To guard against ambiguous study findings that can occur when exposures are mixed, it is critical that future epidemiologic studies include information about the degree of association between task-level stressors. Future research on work organization determinants of task-level stressors, and their coincident occurrence in jobs with greater specialization, may provide promising new insights into the nature of risk for MSD and effective prevention strategies. 相似文献
92.
Primary cultures of neonatal rat aortic smooth muscle cells inoculated at high densities (1 X 10(6) cells/25 cm2 Falcon flask) with adequate nutrient media and pH control grow rapidly and form multilayers of cells with typical "hill and valley" organization. After 10 days growth insoluble elastin formation could be visualized by phase contrast microscopy as small particles which grew rapidly to become larger irregular refractile aggregates and later coalesced to form larger aggregates and small fibres. With light and electronmicroscopy, elastin was the predominant matrix protein formed, with the "hill regions" of cultures containing abundant elastin aggregates and some collagen. In 2-week-old cultures differentiation could be observed within the cell multilayer. The older deeper cells contained more protein synthesis organelles and myofilaments and were in close association with large often coalescing elastin aggregates; compared to younger more superficial cells which contained more free polyribosomes less myofilaments, and were associated with fewer and small elastin aggregates. In older cultures this differentiation was not apparent; the cells contained many myofilaments, dense bodies, and lysosomes. Elastin aggregates and newly formed elastic fibres were abundant in the matrix. Quantitative analysis of insoluble elastin formation in the cell layer during the 4-week culture period indicated continuous biosynthesis and deposition which paralleled that of desmosine formation. Amino-acid analysis of a hot alkali insoluble residue (regarded as elastin) from 30-day-old cultures gave a profile identical with neonatal rat aortic elastin in vivo. Insoluble collagen formation in the cell layer tended to plateau after the log phase of growth was completed (10 days). Proteoglycans were found predominantly in the supernatant media. Glycosaminoglycan analysis revealed a profile of dermatan sulphate (32%), chondroitin 4-sulphate (43%), keratan and heparan sulphate (30%), with only a trace of hyaluronic acid. This study indicates that primary cultures of neonatal rat aortic smooth muscle cells remain differentiated in culture and have the unique capacity to continue to synthesize and deposit large amounts (mg) of insoluble elastin which aggregate and from elastic fibres in vitro. 相似文献
93.
Uday B. Pal Scott A. MacDonald David W. Woolley Adam C. Powell 《Metallurgical and Materials Transactions B》2005,36(2):209-218
Two techniques are described for the enhancement of the kinetics of reduction of iron oxide from slags by carbon in molten
iron. Laboratory experiments have shown that the rate of iron oxide reduction by carbon-saturated iron can be increased by
5 to 10 times when the reaction is carried out under a reduced-pressure atmosphere. This effect is thought to be the result
of the increased volumetric gas evolution through the slag layer and the associated increase in slag stirring. A model is
presented, which relates the mass-transfer coefficient for ferrous ions in the slag to its stirring that is controlled by
varying the ambient pressure. Additional laboratory experiments examined the electrochemical nature of iron oxide reduction
from slag by carbon in liquid iron. Results indicate that the reduction of iron oxide from slag is increased in the presence
of an applied electric field. The external circuit allows for the separation of the half-cell reactions associated with iron
oxide reduction and decarburization and increases the reaction area available for the individual reactions. These results
have significant implications for several important slag metal reactions, which occur during ironmaking and steelmaking operations. 相似文献
94.
MacDonald Angus W. III; Goghari Vina M.; Hicks Brian M.; Flory Janine D.; Carter Cameron S.; Manuck Stephen B. 《Canadian Metallurgical Quarterly》2005,19(6):814
Convergent and divergent validity are critically important in developing psychological measures that reveal interpretable deficits in disordered populations. This article reports on 2 studies that evaluated the validity of context processing measures. In Experiment 1, a confirmatory factor analysis of data from 481 healthy adults established the convergent validity of 2 context processing measures and showed that context processing accounted for significant amounts of variance in standard IQ and working memory measures. In Experiment 2, 20 schizophrenia patients, 16 of their healthy siblings, and 28 controls were evaluated using a novel, short context processing measure, the dot pattern expectancy (DPX) task. The DPX was sensitive to specific deficits in schizophrenia patients and their healthy siblings. These findings support the construct validity of context processing measures, suggest context processing is a component of intellectual functioning, and demonstrate that brief context processing measures remain sensitive to psychopathological deficits. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
95.
Sean MacDonald 《华东电力》2003,32(11):73-76
联合循环机组日益广泛应用于发电厂。与传统的燃煤机组相比 ,联合发电厂的设备及安装成本、发电效率高 ,而且对环境影响小。余热锅炉 ( HRSG)是联合循环机组的一个组成部分。虽然 HRSG的热负荷比传统锅炉低 [1] ,但锅炉水化学却很重要。因此 ,新建 HRSG的化学清洗一直受到关注。传统的新建锅炉中存在油脂 ,氧化皮及焊渣等 ,其化学清洗是为了除去这类杂质以保障机组的正常启动及运行。HRSG系统中存在类似的杂质 ,但 HRSG由两到三个压力不同的蒸汽发生回路所组成 (见图 1 ) ,化学清洗较为复杂。这种锅炉结构一般需要多步或扩大性化学… 相似文献
96.
In this paper, we review an extension of the learning rules in a Principal Component Analysis network which has been derived to be optimal for a specific probability density function. We note that this probability density function is one of a family of pdfs and investigate the learning rules formed in order to be optimal for several members of this family. We show that, whereas we have previously (Lai et al., 2000; Fyfe and MacDonald, 2002) viewed the single member of the family as an extension of PCA, it is more appropriate to view the whole family of learning rules as methods of performing Exploratory Projection Pursuit. We illustrate this on both artificial and real data sets. 相似文献
97.
98.
99.
Heather MacDonald Jacqueline Nelson George Galster Yin Paradies Kevin Dunn Rae Dufty-Jones 《Urban Policy and Research》2016,34(4):373-385
Investigating differential treatment in rental housing markets is important to ensure that renters are not discriminated against based on their personal characteristics. However, little Australian research has focused systematically on this question. This paper reports the results of a study that used paired tests to estimate the extent of differential treatment of Anglo, Indian, and Muslim Middle Eastern renters in the Sydney metropolitan housing market. We find statistically significant differences in treatment on several measures, including the likelihood an agent will offer an individual appointment, will provide additional information about other housing, will provide additional information about completing the application form, and will contact a prospective renter after an inspection. 相似文献
100.
Leo MacDonald Ann Sherman 《Canadian Journal of Science, Mathematics, & Technology Education》2013,13(2-3):133-147
Abstract The focus of this paper is an examination of mentorship relationships developed as a result of six students’ participation in a local community science centre sponsored through an NSERC/CRYSTAL project. Each year, a number of students participate in after‐school activities sponsored by the community science centre. Much of this work involves a one‐to‐one approach, with a middle years or high school student working with a professor partner. The professor acts as a mentor to the student, facilitating learning in a manner not always feasible within a school setting with large class sizes. For some students this research may be the basis of a science fair project; for others if is simply a study based on individual interest. Mentored students were interviewed about the nature of that mentorship, with the goal of describing the experience from the students’ perspective. Questions focused on the student's experience of working with a mentor, including how the mentorship relationship was formed, what the importance of the voluntary nature of mentoring was, what the benefits and challenges of working with a mentor were, how the mentorship relationship affected the level of content knowledge the student gained, and what effect the mentoring relationship had on the student's continuing interest in science. The mentorship program offers students the opportunity to work within a developing community of practice. 相似文献