Physiologic regeneration of corneal epithelium following exposure to constant magnetic fields of super-high intensity]

The mitotic index of mouse corneal epithelium was studied during and after 0.5-- 24 hours exposures to 9.9-39.4 kilooersteds constant magnetic fields. It was shown that 0.5, 1 and 3 hours exposures to a 39.4 kilooersteds constant magnetic field inhibited the mitotic activity whereas 8 and 24 hours exposures caused its stimulation. The value and rate of mitotic index alterations decrease with a decrease of field strength. No changes were found in the frequency of aberrant mitoses or in the number of cells per one field of microscopic vison.     

Schizophrenic inability to disattend from strong aspects of meaning.

Tested R. L. Cromwell and P. R. Dokecki's (1968) theory that excessive response by schizophrenics to strong aspects of meaning of words and deficient response to weak aspects of meaning reflect an inability to disattend from strong aspects of meaning. 79 schizophrenics (40 off and 39 on drugs) were given 2 multiple-choice subtests asking for identification of aspects of meaning of words. Items of one subtest contained both a strong and a weak aspect of meaning and items of the other contained 2 weak aspects of meaning. The subtests had been matched on difficulty and reliability for 166 normal Ss. The schizophrenics identified weak aspects of meaning no worse when strong aspects of meaning were present than when they were absent. Findings argue against Cromwell and Dokecki's theory. Schizophrenics' excessive response to strong aspects of meaning on other tasks probably reflects a defect in screening and a resultant heightened expression of a normal bias. (15 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Inactivation of Semliki Forest Virus in aerosols

Purified Semliki forest virus in aerosols is inactivated rapidly at 40% and above 70% relative humidity. At all humidities tested the decay of virus infectivity runs parallel with the decrease in hemagglutination activity, whereas the biological integrity of the virus ribonucleic acid is preserved. Also, free infectious ribonucleic acid is stable after spraying at all relative humidities. Evidence is presented for the hypothesis that above 20% relative humidity, virus inactivation in aersols is mainly due to surface-dependent factors, damaging the virus coat.     

Nitrous oxide "analgesia": resemblance to opiate action

Nitrous oxide produced a dose-related "analgesia" in mice (median effective dose, 55 percent). The analgesia was evaluated by means of a phenylquinone writhing test. Narcotic antagonists or chronic morphinization reduced nitrous oxide analgesia. Either nitrous oxide releases an endogenous analgesic or narcotic antagonists have analgesic antagonist properties heretofore unappreciated.     

Accessory artificial circulation in complex treatment of experimental acute toxic pulmonary edema

In experiments on 50 dogs with toxic acute edema of the lung, induced with intravenous injection of 0.1% silver nitrate, the authors have studied the efficacy of accessory artificial circulation and "conservative" therapy. During the perfusion a discharge of the right portions, adequate extracorporeal gas metabolism, normalization of blood gas and acid-base balance were noted; an intensity of pulmonary edema is descreased. An intensive therapy for pulmonary edema was found to be more effective in association of "conservative" treatment with venoarterial perfusion and blood oxygenation.     

Stimulation of intestinal degeneration by oestradiol and testosterone implantation in the migrating river lamprey, Lampetra fluviatilis L

Of 325 patients with retinal detachments, 110 patients (34%) had aphakic eyes. These detachments were subdivided into three types based on their clinical appearance during indirect ophthalmoscopy and slit-lamp biomicroscopy. Fifty-two patients (47%) had aphakic detachments (Type 3), categorized by small tears due to traction along a prominent posterior or vitreous base and the absence of visible retinal degeneration. Fifty of the 52 patients in this group were operated on by using a modification of the nondrainage procedure developed by Custodis, and employing cryosurgical coagulation and an external encircling buckle using a 3-mm silicone sponge. The sponge was secured beneath the retinal tear, and its length was shortened to produce a moderately elevated buckle. Although 50% of retinal tears were open at the end of the operation, 60% of all eyes operated on without drainage reattached in 16 hours, 90% in one week, and the remainder in two weeks. Visual acuity of 70% of these patients was 6/15 (20/50) or better when tested six months after surgery. The operation did not wall away peripheral fluid, but closed retinal tears completely, reduced circumferential vitreous traction, and avoided drainage of subretinal fluid.     

On the question of an electrokinetic requirement for phospholipase C action

The phospholipase C of clostridium welchii (alpha toxin) has an absolute requirement for trace quantities of Ca2+. It attacks pure phosphatidylcholine particles (smectic mesophases) having a close-packed bilayer structure only when their surface zeta potential is made positive by the addition of certain divalent ions (e.g., Ca2+) to the aqueous phase or by the presence of low concentrations of long chain cations to the lipid. Alternatively, if the rotational freedom of individual phospholipid molecules is increased by the insertion of short n-alkanols (e.g., hexanol) into the bilayer or when a monolayer of the substrate at an air/water interface is expended, enzymic hydrolysis can occur without any requirement for a net postive charge on the surface.     

Effectiveness of a laboratory-scale vertical tower static chamber steam pasteurization unit against Escherichia coli O157:H7, Salmonella typhimurium, and Listeria innocua on prerigor beef tissue

A laboratory-scale vertical tower steam pasteurization unit was evaluated to determine the antimicrobial effectiveness of different exposure times (0, 3, 6, 12, and 15 s) and steam chamber temperatures (82.2, 87.8, 93.3, and 98.9 degrees C) against pathogens (Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria innocua) inoculated onto prerigor beef tissue. Samples were collected and microbiologically analyzed immediately before and after steam treatment to quantify the effectiveness of each time-temperature combination. The 0-s exposure at all chamber temperatures (cold water spray only, no steam treatment) was the experimental control and provided < or = 0.3 log CFU/cm2 reductions. Chamber temperatures of 82.2 and 87.8 degrees C were ineffective (P > 0.05) at all exposure times. At 93.3 degrees C, significant reductions (> 1.0 log CFU/cm2) were observed at exposure times of > or = 6 s, with 15 s providing approximately 1 log cycle greater reductions than 12 s of exposure. The 98.9 degrees C treatment was consistently the most effective, with exposure times of > or = 9 s resulting in >3.5 log CFU/cm2 reductions for all pathogens.