General restoration filter for vibrated-image restoration

Mechanical vibrations are often the principal cause of image degradation. Low temporal-frequency mechanical vibrations involve random image degradation that depends on the instant of exposure. Exact restoration requires the calculation of a specific filter unique to each vibrated image. To calculate the restoration filter for each image, one needs the specific optical transfer function unique to the motion in the image. Therefore the instant of exposure and the motion function have to be measured or estimated by some other means. We develop a restoration filter for individual images blurred randomly by low-frequency mechanical vibrations. The filter is independent of the instant of exposure. The filter is designed to give its best performance averaged over a complete ensemble of vibrated images. Although when applying the new filter to any vibrated image the restoration achieved is slightly poorer than that achieved with an exact filter unique to the specific motion function, the new filter has the advantage of simplicity.     

Speckle noise in laser bar-code-scanner systems

We present a theoretical model and its experimental verification for speckle-induced noise in laser-based bar-code-scanner systems. We measured the dependence of the signal-to-speckle-noise ratio on distance, spot size, and detector size. Analyses of the power spectra of both the speckle noise and of the measured surface profiles of different substrates suggest that the paper surface granularity can be approximated by a white Gaussian noise process, thus confirming the assumption of the theoretical model.     

Evolution of carbohydrate metabolic pathways

Current studies of hyperthermophilic archaea and bacteria, the phylogenetically deepest-rooted and slowest-evolving extant organisms known, are allowing new insights into the nature of presumably ancient metabolic pathways. The apparent common occurrence of modified non-phosphorylated Entner-Doudoroff (ED) pathways among saccharolytic archaea and the absence of the conventional Embden-Meyerhof-Parnas (EMP) mode of glycolysis indicate that the ED pathway is the older route of carbohydrate dissimilation. However, gluconeogenesis via the "reversed" EMP route has been found in archaea. Thus, the EMP pathway was probably an anabolic pathway to begin with; its catabolic role came later, with the evolution of fructose phosphate kinases, using ATP, ADP or pyrophosphate as phosphate donors. Similarly, the presence of reductive reactions of the citric acid cycle in anaerobic archaea and the most deeply rooted bacteria, including autotrophs, indicates that the citric acid cycle was originally a reductive biosynthetic pathway.     

Effect of sinus denervation and vagotomy on c-fos expression in the nucleus tractus solitarius after exposure to CO2

Exposure to hypercapnia and electrical stimulation of the carotid sinus nerve (CSN) has been shown to induce c-fos expression in several brain stem regions including the nucleus tractus solitarius (NTS). To test whether the labeled neurons were activated directly by hypercapnia or secondarily via the carotid bodies (sinus nerve), adult rats were exposed to either air or 14-16% CO2 for 1 h. Experiments were done on eight groups: (1) exposure to air, (2) exposure to CO2, (3) chronic CSN denervation/CO2, (4) chronic unilateral CSN denervation/CO2, (5) chronic sham CSN denervation/CO2, (6) anesthetized/CO2, (7) anesthetized and acute vagotomy/CO2, and (8) premedicated with morphine, 10 mg s.c., 20 min before exposure to CO2. After exposure to CO2 or air the rats were anesthetized, perfused with 4% paraformaldehyde and the brains processed for immunohistochemical staining for c-fos protein using the PAP (i.e. peroxidase anti-peroxidase) technique. Labeled neurons in the area of the NTS in every second 50- "mu"m section were counted and their position plotted using a microscope and camera lucida attachment. Rats exposed to CO2 had a significantly greater number of labeled neurons in the NTS than those exposed to air. Other interventions, such as CSN denervation, surgery, anesthesia, vagotomy or injection of morphine did not significantly affect the level of c-fos expression in rats exposed to hypercapnia, indicative of central stimulation rather than secondary peripheral input. These responsive neurons may be part of a widespread central chemoreceptive complex.     

Severe facial clefting, limbic dermoid, hypoplasia of the corpus callosum, and multiple skin appendages: severe frontofacionasal "dysplasia" or newly recognised syndrome?

We report on a child with severe midline facial cleft, bilateral cleft lip and palate, telecanthus, S-shaped palpebral fissures, limbic dermoid, midface hypoplasia, hypoplastic corpus callosum, and multiple skin appendages. This case may be an example of severe frontofacionasal "dysplasia" or a newly recognised syndrome.     

Ambulatory urodynamics: extramural testing of the lower and upper urinary tract by Holter monitoring of cystometrogram, uroflowmetry, and renal pelvic pressures

This article elucidates the clinical applicability and state of the art of ambulatory urodynamics. Ambulatory urodynamics have evolved into practical investigations like EAC, HFM, and EAC combined with renal pelvimetry. EAC has been shown to be the method of preference if detrusor overactivity is involved. Conventional filling cystometry has proved to be an unreliable way to exclude detrusor instability. De novo instability after suspension surgery often indicates that an existing detrusor overactivity was not identified preoperatively. EAC including flowmetry has shown considerable variance in obstructive and contractility parameters in males with LUTS indicative for BPH. This raises doubt whether the clinical flow analysis is the suitable "gold standard" as advocated by the ICS. For a real break through of EAC, less complex automatic analysis is necessary. HFM is a newer method within the range of ambulatory urodynamic tests. It has not yet been completely evaluated. But, because the technique is analogous to the office flowmetry, noninvasive and very well accepted by the patients, it is expected to be widely used. This expectation is strengthened by the fact that HFM seems to show individual therapeutic efficacy of drugs, such as alpha-blockers. As a research tool to evaluate efficacy, it is far more powerful than conventional methods because of the reduction of within-patient standard deviation to about 10%. Finally, EAC combined with pelvimetry offers a promising method for the clinical evaluation of a combined dysfunction of upper and lower urinary tract.     

Fast computation of the difference of low-pass transform

This paper defines the difference of low-pass (DOLP) transform and describes a fast algorithm for its computation. The DOLP is a reversible transform which converts an image into a set of bandpass images. A DOLP transform is shown to require O(N2) multiplies and produce O(N log(N)) samples from an N sample image. When Gaussian low-pass filters are used, the result is a set of images which have been convolved with difference of Gaussian (DOG) filters from an exponential set of sizes. A fast computation technique based on ``resampling' is described and shown to reduce the DOLP transform complexity to O(N log(N)) multiplies and O(N) storage locations. A second technique, ``cascaded convolution with expansion,' is then defined and also shown to reduce the computational cost to O(N log(N)) multiplies. Combining these two techniques yields an algorithm for a DOLP transform that requires O(N) storage cells and requires O(N) multiplies.     

Maintenance of Response Readiness in Patients With Parkinson's Disease: Evidence From a Simple Reaction Time Task.

The authors explored the effect of Parkinson's disease (PD) on the generation and maintenance of response readiness in a simple reaction time task. They compared performance of idiopathic PD patients without dementia, age-matched controls, and younger controls over short (1-, 3-, and 6-s) and long (12- and 18-s) foreperiod intervals. After each trial, the authors probed memory for visual information that also had to be maintained during the trial interval. Patients and controls did not differ overall in their ability to maintain readiness over long delays. However, within the PD group only, errors in maintaining visual information were correlated with difficulty in maintaining readiness, suggesting that systems impaired in PD may facilitate the maintenance of processing in both motor and cognitive domains. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Distributed Virtual Reality environments based on rewriting systems

Ideally, virtual worlds should be dynamic, mutable, and complex in order to be attractive for immersed users. As such worlds can be designed easily by rewriting techniques, we propose a distributed Virtual Reality (VR) system that is based on an interactive animation system using a rewriting technique for geometric and behavioral modeling. The emphasis is on concepts and extensions for the integration of user immersion, user interaction, and networking into a rewriting-based animation system, Finally, the modeling of a ball game with two immersed users, as well as a virtual park, serve as case studies to illustrate the proposed concepts and extensions.