Software fault prediction using Nonlinear Autoregressive with eXogenous Inputs (NARX) network

This paper explores a new approach for predicting software faults by means of NARX neural network. Also, a careful analysis has been carried out to determine the applicability of NARX network in software reliability. The validation of the proposed approach has been performed using two real software failure data sets. Comparison has been made with some existing parametric software reliability models as well as some neural network (Elman net and TDNN) based SRGM. The results computed shows that the proposed approach outperformed the other existing parametric and neural network based software reliability models with a reasonably good predictive accuracy.     

In vitro growth and drug sensitivity of tumor colony-forming units from human tumor xenografts

To investigate the feasibility of using tissue obtained from human tumor xenografts for in vitro screening of antineoplastic agents, we grew human tumor colony-forming units (CFU) in semisold agar from xenografts serially passaged in nude mice. Growth of human tumor CFU was accomplished from nine xenografts representing five different histological tumor types (ovarian carcinoma, adenocarcinoma of the colon, malignant melanoma, epidermoid carcinoma of the lung, and malignant astrocytoma). Cloning efficiency ranged from 0.04 to 0.1% and showed significant variability both between tumor types and between individual animals bearing the same type of xenograft. A high percentage of tumor CFU was in S phase [47 +/- 20% (S.D.)] as determined by the thymidine "suicide" technique. The number of tumor CFU observed increased linearly with increasing numbers of cells plated. In vitro drug sensitivity of the tumor CFU was assessed to Adriamycin, cis-platinum, and melphalan. The patterns of drug sensitivity were found to be reproducible and stable over a period of 9 months. Drug sensitivity curves to Adriamycin for five xenografts representing four tumor types showed complex patterns with plateau portions similar to those described for tumor CFU from primary tumors. The rank order of sensitivity of the tumors was compared to that of normal granulocyte-macrophage progenitors and, with the exception of the melanomas, was found to correlate well with clinical experience (order of sensitivity = colon less than ovary less than bone marrow). Growth of human tumor CFU from xenografts represents a reproducible and stable means for the study of the biology of tumor CFU and has potential applications as a means for screening new anticancer agents.     

Cashing in on Caching: An Architecture for Time-Bounded Knowledge-Based Problem Solving

Knowledge-based computing, in general, suffers from an inherent open-endedness that precludes its application in time-bounded domains where an answer must be computed within a stipulated time limit. We examine a two-way improvement of the shortcomings: a knowledge representation scheme that provides easy access to relevant knowledge and thereby reduces search time, and a reasoning scheme that is algorithmic in nature and thus makes computational requirements meaningfully estimable.In this work, we offer a cache-based architecture that is capable of both storing knowledge in different formats (e.g. rules, cases), and invoking an appropriate reasoning scheme to fit the available computing time. The cache helps in retrieving the most relevant pieces of knowledge (not only exact matches) required for solving a given problem. This cache relies on a reasoning tactic, knowledge interpolation, that can generate a solution from two near-matches in an algorithmic way, to generate time-bounded solutions. We illustrate the design of such a cache for solving resource allocation problems in the domain of shortwave radio transmission and evaluate its performance in observing imposed temporal bounds.     

Influential rule search scheme (IRSS) - a new fuzzy pattern classifier

Automatic generation of fuzzy rule base and membership functions from an input-output data set, for reliable construction of an adaptive fuzzy inference system, has become an important area of research interest. We propose a new robust, fast acting adaptive fuzzy pattern classification scheme, named influential rule search scheme (IRSS). In IRSS, rules which are most influential in contributing to the error produced by the adaptive fuzzy system are identified at the end of each epoch and subsequently modified for satisfactory performance. This fuzzy rule base adjustment scheme is accompanied by an output membership function adaptation scheme for fine tuning the fuzzy system architecture. This iterative method has shown a relatively high speed of convergence. Performance of the proposed IRSS is compared with other existing pattern classification schemes by implementing it for Fisher's iris data problem and Wisconsin breast cancer data problems.     

Susceptibility to tropical theileriosis of calves born to dams immunized with Theileria annulata (Hisar) cell culture vaccine

Epidemiological evidence suggests that millet might play a role in the etiology of endemic goiter. Recently, we showed that a traditional fermentation procedure of two pearl millet (Pennisetum americanum L. Lecke) cultivars grown in Sudan modified their effects on the weight of the thyroid gland and thyroid hormone profile in rats. In the present study, we report that this fermentation procedure reduced the ash contents of millet by about 40% and removed considerable amounts of Mg (>50%), Zn (27-39%) and K (45%). Other minerals (Ca, Fe, Cu) were not affected. Feeding of one fermented cultivar resulted in significant reduction in bone Mg and Zn contents, whereas feeding of the other fermented cultivar resulted in reduction of bone Mg only. Dietary Mg intake and bone Mg contents correlated negatively with serum T3. Groups fed the millet diets had higher serum Se level compared to those fed wheat or casein diets and feeding of fermented millet resulted in a further increase in serum Se level. Thus our data indicate that in rats the enhanced effects of millet on the thyroid induced by fermentation is likely related to removal of minerals from millet and/or chemical transformation of the goitrogens contained in millet.     

A preclinical study of the effect of the animal polysaccharide chonsurid on reparative osteogenesis of the jaws

Experimental studies making use of morphological and x-ray methods demonstrated that in comparison with control (filling of mandibular bone defects with blood clots) chonsuride, an animal polysaccharide, promoted earlier filling of postoperative bone cavities with connective tissue replacement of this tissue with coarse-fiber bone tissue. Secondary restructuring and mineralization of bone regenerate were enhanced as well.     

Transformation calibration of a camera mounted on a robot

The paper describes the accurate calibration of the camera transformation for a vision system consisting of a camera mounted on a robot. The calibration includes an analysis of the linearity of the camera. A knowledge of the camera transformation allows the three-dimensional position of the object points to be determined using triangulation.     

Combined removal of BTEX in air stream by using mixture of sugar cane bagasse, compost and GAC as biofilter media

Biofiltration of air stream containing mixture of benzene, toluene, ethyl benzene and o-xylene (BTEX) has been studied in a lab-scale biofilter packed with a mixture of compost, sugar cane bagasse and granulated activated carbon (GAC) in the ratio 55:30:15 by weight. Microbial acclimation was achieved in 30 days by exposing the system to average BTEX inlet concentration of 0.4194 gm(-3) at an empty bed residence time (EBRT) of 2.3 min. Biofilter achieved maximum removal efficiency more than 99% of all four compounds for throughout its operation at an EBRT of 2.3 min for an inlet concentration of 0.681 gm(-3), which is quite significance than the values reported in the literature. The results indicate that when the influent BTEX loadings were less than 68 gm(-3)h(-1) in the biofilter, nearly 100% removal could be achieved. A maximum elimination capacity (EC) of 83.65 gm(-3)h(-1) of the biofilter was obtained at inlet BTEX load of 126.5 gm(-3)h(-1) in phase IV. Elimination capacities of BTEX increased with the increase in influent VOC loading, but an opposite trend was observed for the removal efficiency. The production of CO(2) in each phase (gm(-3)h(-1)) was also observed at steady state (i.e. at maximum removal efficiency). Moreover, the high concentrations of nitrogen in the nutrient solution may adversely affect the microbial activity possibly due to the presence of high salt concentrations. Furthermore, an attempt was also made to isolate the most profusely grown BTEX-degrading strain. A Gram-positive strain had a high BTEX-degrading activity and was identified as Bacillus sphaericus by taxonomical analysis, biochemical tests and 16S rDNA gene analysis methods.