Diskitis caused by Actinobacillus actinomycetemcomitans

A 32-year-old man with acquired immunodeficiency syndrome (AIDS) admitted to the hospital for treatment of visceral leishmaniasis was inadvertently given 10 times the prescribed first dose of sodium stibogluconate ([Sb] 6.5 g instead of 0.65 g). He experienced no immediate major toxicity during the first 48 hours, but a significant rise of pancreatic enzyme activities was observed (amylase at 10 times the upper limit of normal, lipase at 50 times the upper limit of normal) without clinical signs or indications on computed tomography (CT) of pancreatitis. The third day after the overdose, he developed appendicitis, which appeared coincidental; he recovered uneventfully from surgery. Most of the overdose of Sb was eliminated within the first few hours. Pharmacokinetics remained linear; the rapid, long elimination half-lives (2.7 hours and 54 hours, respectively) were similar to those in previously published results. The administration of a chelating agent, dimercaptosuccinic acid (DMSA), 72 hours after the Sb overdose did not modify the pharmacokinetics of the medication.     

The Positive Magnetic Susceptibility for Rb3C60 Superconductor and the Differential Paramagnetic Effect

AC magnetic susceptibility of Rb₃C₆₀ superconductor as a function of temperature was measured in an applied static magnetic field perpendicular to the AC magnetic field. The peaks in real part of AC susceptibility curves located in the transitional temperature indicate that there may exist the differential paramagnetic effect (T) = dM/dH > 0 in the specimen. The amplitude of the peak and the temperature of diamagnetic onset are proportional to intensity of the applied field, and upon cooling the peaks occur before the transition temperature of zero field. Through discussing and comparing our experimental result with those reported previously, we have put forward a new opinion on producing condition of the differential paramagnetic effect (DPE).