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901.
902.
G Scalise MR Mazaheri AS Hamblin P Gioannini AJ Zuckerman DC Dumonde 《Canadian Metallurgical Quarterly》1976,22(3):257-260
Although the rise in blood copper is associated with onset of the acute haemolytic crisis of chronic copper poisoning in sheep, the sudden fall in erythrocyte glutathione is apparently not due to a direct action of the copper. Moreover the reduced glutathione of the red cells is converted to some form that is not capable of regeneration by the pentose-phosphate mechanism. Only negligible inhibition of the pentose-phosphate enzymes occurs. As the haemolysis proceeds, there is a rapid recovery of erythrocyte glutathione levels, and a marked increase in pentose-phosphate enzyme activity, consistent with influx of young red cells. It seems that the release of copper into blood from liver at the haemolytic crisis is associated with an increase of the oxidative state of the blood, possibly by simultaneous release of other components from the liver. 相似文献
903.
904.
In 37 patients of nephrotic syndrome, serum protein levels, protein fractions and urinary levels of proteins and their fractions were determined. The findings of serum levels of proteins and their fractions were compared with an equal number of age and sex matched controls. Twenty three patients showed selective and 14 non-selective proteinuria. Most of the patients with selective proteinuria showed good response to steroids therapy while those with non-selective proteinuria did not respond. 相似文献
905.
906.
AS Manoguerra 《Canadian Metallurgical Quarterly》1976,33(10):1088-1090
A fatal case of iron poisoning in a suicide attempt is reported, and the toxicity and pathophysiology of iron are discussed. The four phases of the clinical features of iron poisoning are presented, and the general treatment of iron toxicity is discussed. 相似文献
907.
908.
AS Daoud J Jarmolych JM Augustyn KE Fritz JK Singh KT Lee 《Canadian Metallurgical Quarterly》1976,100(7):372-379
Advanced complicated atherosclerosis was produced in the abdominal aorta of swine by a combination of mechanical injury and high-cholesterol, high-fat diet for four months. After removal of the high-cholesterol diet and placing the animal on swine mash for 14 months, there was a significant (P less than .005) decrease in size of lesions with remodeling of the intima toward a smooth surface. Sudanophilia had virtually disappeared and atheromas were almost absent in the regression group, as were thrombosis and hemorrhage in plaques. Cell proliferation, as judged by the number of labeled cells in autoradiography, was less pronounced in this group. There was no decrease in the numbers of segments showing calcification; however, the size of the calcified areas was smaller in the regression group than in the base line. The data suggest that advanced atherosclerosis is susceptible to regression on removal of the atherosclerotic stimulus. 相似文献
909.
910.