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A morphological examination of 27 rats flown onboard the biosatellite and sacrificed on the 1st-2nd and 26-27th postflight days demonstrated no significant changes in the structural organization of the vital organs and systems of the animal body. It was, however, found that the space exposure induced morphologically detectable changes in the musculo-skeletal system, hemo- and lymphopoiesis, hypothalamic-pituitary-adrenal system and the juxtaglomerular apparatus of the kidneys. The changes were reversible and nonspecific, and could be seen in animals exposed to ground-based hypokinetic and other stress experiments. Postflight the animals developed some reactions that were similar to those in humans. This helps to identify the morphological substrate of certain changes in the human body and to investigate their pathogenesis.  相似文献   
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The nature of disturbed thinking is explained from two different psychological perspectives and six major types of thought disorder are presented, classified, and discussed. The overlap between these different types of thought disturbance and some possible functions of disturbed thinking are outlined. A heuristic model for detecting thought disorder is presented; and, in addition, some complex conceptual and research issues involved with investigating and systematizing knowledge about disturbed thinking are explained.  相似文献   
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Jejunal lamina propria plasma cells and eosinophils and intraepithelial lymphocytes were raised in coeliac children on gluten-containing diets, but only intraepithelial lymphocytes were increased in patients on gluten-free diets. In contrast, lamina propria lymphocytes were reduced in children with coeliad disease on gluten-containing diets but were normal in paitents on gluten-free diets. In children with coeliac disease who were studied serially, lamina propria plasma cells and eosinophils and intraepithelial lymphocytes increased, and lamina propria lymphocytes decreased, within three months of the reintroduction of gluten to the diet. These observations are essentially similar to those made in the adult form of the disease and suggest that more than one type of immunological reaction is involved in the pathogenesis of the jejunal lesion.  相似文献   
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We studied in 130 parturients during childbirth the effects of general anaesthesia by Alfatesine on the state of the foetus at birth. The examinations took into account the APGAR score, blood gas analysis, pH, bases excess in the umbilical artery and vein and the foetal EEG. The subjects are divided into three groups: prophylactic caesarians, extractions during labor in the absence of any foetal distress and extractions for reasons of acute or chronic foetal distress. The results are evaluated in comparison with the same tests conducted on a series of newborn infants in normal conditions and without anaesthesia. The APGAR score is hardly affected by the Alfatesine; the EEG is perturbed (but without any clinical manifestations) during the two hours following delivery. However, theses modifications are less pronounced than those observed with barbiturates. The study of blood gases and pH shows lower values under anaesthesia than without.  相似文献   
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