The treatment of atypical manias with finlepsin-retard

The article presents results of clinical trial of finlepsine-retard. Objectivized parameters characterizing the time course of psychopathologic symptoms were studied in certain concentrations of finlepsine and beta-endrofin in blood serum. Atypical maniac states do not easily respond to therapies but finlepsine-retard gives the modern psychopharmacotherapy a new horizon.     

Sick Building Syndrome: Cleanliness is Next to Healthiness

There is evidence that sick building syndrome (SBS) is caused, in part, by indoor surface pollution (ISP): contaminants such as dust, fibres and micro-organisms, deposited on or in surfaces in buildings. A study is described which clarifies the relative importance of a number of possible causes of SBS in a single building. The building, which had a high initial prevalence of SBS symptoms, was used in a doubleblind controlled intervention study with weekly symptom questionnaires. The four interventions were: ventilation system cleaning, air filtration, hot-water extraction cleaning of chairs and carpets, plus high grade filter vacuuming and dusting, and dust mite treatment (application of liquid nitrogen). Only the last two interventions brought about a reduction in symptoms. It is concluded that cleaning which effectively reduces ISP can reduce SBS symptoms. This may be related to the presence of dust mites in furnishings. Improved cleaning may entail better cleaning specifications and/or consideration of requirements for cleaning when selecting and positioning office furniture. If ISP and the temporary local pollution levels created by it are a problem, then monitoring of ambient conditions (by instruments or by human assessors) will not adequately represent the conditions to which occupants are exposed     

Hyaline cartilage at porta hepatis in extrahepatic biliary atresia

Hyaline cartilage was found on microscopy of sections of the extrahepatic biliary tree in two infants with extrahepatic biliary atresia (EHBA). Respiratory epithelium was not present, and the cartilage did not seem to block the bile duct lumen. Hyperbilirubinemia was manifest in one infant on the second postnatal day, but clinical courses were otherwise unremarkable. In neither infant was the ductal plate malformation found on light microscopy of liver biopsy specimens, and in neither infant was visceral topography abnormal. Hyaline cartilage at the porta hepatis appears to be a novel finding in EHBA. Its significance remains to be defined.