Positional regulators of bone tissue--a basis for the autoregulatory mechanism of the development and reproduction of osteoporosis

A hypothesis on autoregulatory mechanism of reproduction of bone matrix structural changes was proposed resulting from the theoretical study based on author's own data and data documented in literature. This mechanism seems to underly osteoporosis development. All etiological factors of osteoporosis reported were united into a common pathogenetic mechanism on the basis of this conception.     

Possible mechanism of hypothalamic regulation of endocrine pancreatic function in mice of the diabetic strain C57bl/KsJ

In mice hetero- and homozygotic in relation to the diabetic gene db, it was shown that the regulation of the pancreatic endocrine function by hypothalamus is mediated at least by two mechanisms: neurohumoral one connected with hormone secretion by paraventricular and supraoptical nuclei and by a neuroconductivity mechanism connected with the ventromedial nucleus and lateral hypothalamic area.     

Computerized spirometers (analysis of problem solving)

It has been experimentally found that larval and pulmonary paragonimiasis types are caused by the trematode Paragonimus westermani ichunensis. The development of either paragonimiasis in nontypical definitive hosts depends on the stage of larval development when they penetrate into the mammal. Only the P. westermani ichunensis trematode is likely to develop with the participation of Juga mollusks on the territory of the Primorye.     

Analysis of the structure of cardiac rhythm during treatment of auricular fibrillation with digitalis

The structure of cardiac rhythm was studied with the help of specialized computers during digitalization in 60 patients with atrial fibrillation of different etiology. The reduction of the heart contractions rate under digitalization is accompanied by certain changes in the structure of cardiac rhythm: the arrhythmic pattern of the ventricular contractions increases with a predominant growth of the number of long R--R intervals, the transitions from short intervals to longer ones become sharper, and portions of a relatively stable ventricular rhythm appear. Three main types of dynamics of the rhythm structure were distinguished on the basis of the changes in the interval R--R histogram. The described changes in the structure of cardiac rhythm are not specific, but when Digitalis drugs are used alone they can be used as additional criteria for digitalization.