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121.
122.
AV Feofanov VA Ole?nikov AB Tuzikov AI Ianul' EIu Kriukov NV Bovin IR Nabiev 《Canadian Metallurgical Quarterly》1997,23(11):910-918
Neoglycoconjugates based on polyacrylamide and sialic acid with N-acetylneuraminic acid or sialooligosaccharides as side chains were studied by surface-enhanced Raman scattering (SERS) spectroscopy. It had previously been found that these polymers can effectively inhibit influenza virus adhesion. This study revealed the possibility to evaluate, based on the intensity of SERS signals, the overall availability for interaction and the conformational freedom of sialic acid residues in glycoconjugates. The dependence of these two factors on the structure and density of sialylated side chains was studied. The uniformity of distribution of sialylated side chains in conjugates was shown. Comparison of the results of the SERS spectroscopic study of the conjugates and the data on their inhibitory effect on the adhesion of specific strains of influenza virus allowed the identification of the conjugates for which the availability and conformational freedom of sialic acid are the main factors determining their inhibitory properties. A conclusion was also reached about the predominance of one of the mechanisms (competitive inhibition or steric stabilization) in the inhibitory properties of the specific conjugates. 相似文献
123.
124.
E. V. Sokolova N. R. Frage Yu. G. Gurevich V. I. Chumanov 《Powder Metallurgy and Metal Ceramics》1991,30(1):60-63
Translated from Poroshkovaya Metallurgiya, No. 1(337), pp. 68–72, January, 1991. 相似文献
125.
E. V. Astrova D. A. Andronikov M. V. Gorokhov N. K. Zelenina V. M. Kozhevin E. I. Terukov A. A. Tomasov S. A. Gurevich 《Technical Physics Letters》2010,36(6):489-492
We have studied the characteristics of small-scale air-hydrogen fuel cells (FCs) operating in a free-breathing cathode regime.
The cells are provided with a new gas-distributing element on the cathode side, which is based on a silicon plate with narrow
through slots (slotted Si plate). It is shown that the use of a slotted Si plate significantly weakens the dependence of the
FC characteristics on the humidity of environment in a broad temperature range. Indeed, at a fixed temperature, the FC power
only changed within 10% when the relative humidity of the ambient air varied between 50 and 98%. 相似文献
126.
AV Shabunin 《Canadian Metallurgical Quarterly》1997,156(6):77-79
Children during the first few years of their lives, presenting with lymphohypoplastic diathesis were studied for their blood serum content of sodium, potassium, chlorine. Relationship was found of the electrolyte balance to the processes of the lipid peroxidation, activity of the hormonal link of the antioxidant defence system. 相似文献
127.
128.
IuP Slizhenko AV Beliaev AM Zaremba TN Platonova 《Canadian Metallurgical Quarterly》1997,69(5-6):183-190
The fibrinolytic process in the plasma of patients operated for abdominal haemorrhages have been investigated. The results allowed to conclude that the blockade of fibrinolysis did not effect on the course of the disease. The high level of the inhibitors and of the platelets hypoaggregation can be considered as a cause increased of the recurring gastrointestinal haemorrhages. It was demonstrated that the probability of DIC-syndrome development increased at the aggravation of the patient's state after the operation. 相似文献
129.
SKh Degtyarev NA Netesova MA Abdurashitov AV Shevchenko 《Canadian Metallurgical Quarterly》1997,187(2):217-219
1. Ovomucoids were purified from Muscovy duck, domestic duck and domestic goose. 2. Peptide maps of cyanogen bromide-cleaved ovomucoids from Muscovy duck and domestic duck were very similar to one another, but differed from that of goose. 3. Muscovy duck ovomucoid showed the same protease inhibitory pattern as ovomucoid from domestic duck, inhibiting trypsin in the molar ratio of 1:2 and chymotrypsin 1:1. 4. Inhibitory complexes could be detected between chymotrypsin and ovomucoid from both Muscovy and domestic duck, but not from goose, by using non-denaturing gels. 5. No complexes could be detected between DFP-inactivated chymotrypsin and any of the ovomucoids. 6. The results show that of ovomucoid from Muscovy duck more closely resembles that from domestic duck than goose. 相似文献
130.