Experience in the Development and Production of Thermal-Neutron Detectors at the IBR-2 DSC (Review)

Instruments and Experimental Techniques - One of the most important activities of the IBR-2 DSC is the development of detector technologies, which will be used as a basis in designing detectors for...     

Non‐linear exact geometry 12‐node solid‐shell element with three translational degrees of freedom per node

This paper presents the finite rotation exact geometry (EG) 12‐node solid‐shell element with 36 displacement degrees of freedom. The term ‘EG’ reflects the fact that coefficients of the first and second fundamental forms of the reference surface and Christoffel symbols are taken exactly at each element node. The finite element formulation developed is based on the 9‐parameter shell model by employing a new concept of sampling surfaces (S‐surfaces) inside the shell body. We introduce three S‐surfaces, namely, bottom, middle and top, and choose nine displacements of these surfaces as fundamental shell unknowns. Such choice allows one to represent the finite rotation higher order EG solid‐shell element formulation in a very compact form and to derive the strain–displacement relationships, which are objective, that is, invariant under arbitrarily large rigid‐body shell motions in convected curvilinear coordinates. The tangent stiffness matrix is evaluated by using 3D analytical integration and the explicit presentation of this matrix is given. The latter is unusual for the non‐linear EG shell element formulation. Copyright © 2011 John Wiley & Sons, Ltd.     

Nucleolar localization elements in U8 snoRNA differ from sequences required for rRNA processing

U8 small nucleolar RNA (snoRNA) is essential for metazoan ribosomal RNA (rRNA) processing in nucleoli. The sequences and structural features in Xenopus U8 snoRNA that are required for its nucleolar localization were analyzed. Fluorescein-labeled U8 snoRNA was injected into Xenopus oocyte nuclei, and fluorescence microscopy of nucleolar preparations revealed that wild-type Xenopus U8 snoRNA localized to nucleoli, regardless of the presence or nature of the 5' cap on the injected U8 snoRNA. Nucleolar localization was observed when loops or stems in the 5' portion of U8 that are critical for U8 snoRNA function in rRNA processing were mutated. Therefore, sites of interaction in U8 snoRNA that potentially tether it to pre-rRNA are not essential for nucleolar localization of U8. Boxes C and D are known to be nucleolar localization elements (NoLEs) for U8 snoRNA and other snoRNAs of the Box C/D family. However, the spatial relationship of Box C to Box D was not crucial for U8 nucleolar localization, as demonstrated here by deletion of sequences in the two stems that separate them. These U8 mutants can localize to nucleoli and function in rRNA processing as well. The single-stranded Cup region in U8, adjacent to evolutionarily conserved Box C, functions as a NoLE in addition to Boxes C and D. Cup is unique to U8 snoRNA and may help bind putative protein(s) needed for nucleolar localization. Alternatively, Cup may help to retain U8 snoRNA within the nucleolus.     

An electromagnetic-acoustic method for studying stress-strain states of rails

Experimental results of measuring mechanical stresses in R65 rails with the use of the acoustic elasticity effect and an electromagnetic-acoustic method for the input-reception of shear waves are presented. Results of modeling compressive stresses in a rail segment are provided. The experimental results are compared with theoretical estimates for stresses that are induced in a restrained rail by the temperature action. The results of monitoring residual stresses in rails are described for a segment of continuous welded rails.     

Intravascular ultrasound predictors of restenosis after balloon angioplasty of the femoropopliteal artery

The skepticism surrounding the potential benefits of resistance exercise training prevalent just decades ago has evolved over the years to an understanding of the integral nature muscular overload plays in the training programs for athletes. The science of training elite athletes is progressing rapidly, as insights into the physiological adaptations resulting from varying program configurations become available. Resistance training impacts several body systems, including muscular, endocrine, skeletal, metabolic, immune, neural, and respiratory. An understanding and appreciation of basic scientific principles related to resistance training is necessary in order to optimize training responses. Careful selection of the acute program variables in a workout to simulate sports-specific movements is required for optimal transfer of gains made in training to competition. Thus, whether athletes require predominantly eccentric, isometric, slow-velocity, or high-velocity strength or power in their athletic event will dictate the time commitment to each component and form the basis for designing individual workouts. Program variation over a training period is essential to maximize gains and prevent overtraining.     

Computerized spirometers (analysis of problem solving)

It has been experimentally found that larval and pulmonary paragonimiasis types are caused by the trematode Paragonimus westermani ichunensis. The development of either paragonimiasis in nontypical definitive hosts depends on the stage of larval development when they penetrate into the mammal. Only the P. westermani ichunensis trematode is likely to develop with the participation of Juga mollusks on the territory of the Primorye.