Symbolic computation with finite biquandles

A method of computing a basis for the second Yang–Baxter cohomology of a finite biquandle with coefficients in Q$\mathbb{Q}$ and _Zp${\mathbb{Z}}_p$ from a matrix presentation of the finite biquandle is described. We also describe a method for computing the Yang–Baxter cocycle invariants of an oriented knot or link represented as a signed Gauss code. We provide a URL for our Maple implementations of these algorithms.     

Temporal alignment of tissue and arterial data and selection of integration start times for the H(2)(15)O autoradiographic CBF model in PET

A technique has been developed and tested that provides an automated method of temporally aligning the PET tissue activity curve with the arterial activity curve for quantification of cerebral blood flow using the H(2)(15)O autoradiographic model. This technique not only determines the relative time delay between the two curves, but also provides the start time of integration. Variability in computing global cerebral blood flow using this technique is shown to be less than that obtained by trained observers manually selecting parameters and at least as good as that obtained by using another automated alignment technique.     

Identification of two distinct properties of class II major histocompatibility complex-associated peptides

We have examined the interactions of various peptides with the mouse class II major histocompatibility complex molecule I-Ak. The peptides were derived from the model protein hen egg white lysozyme (HEL). The immunodominant peptide of HEL is a 10-mer, residues 52-61. Our previous work established that this sequence contains the key residues for binding and presentation to T cells. Now we show that the binding of this 10-mer sequence resulted in complexes of I-Ak and peptide that, in SDS/PAGE (without boiling the protein), rapidly dissociated from the component alpha and beta chains. The binding interactions were studied in vitro, by incubating purified I-Ak and radiolabeled peptide, or ex vivo, by using antigen-presenting cells incubated with peptides. Peptides with additional residues at either the amino or carboxyl terminus behaved dramatically differently. Complexes of I-Ak with the longer peptides were stable to SDS/PAGE. Very few amino acid additions result in the change from unstable to stable complexes. The important issue here is that when cultured with HEL, antigen-presenting cells selected the HEL peptides containing the 52-61 sequences that favored stability [Nelson, C. A., Roof, R. W., McCourt, D. W. & Unanue, E. R. (1992) Proc. Natl., Acad. Sci. USA 89, 7380-7383]. Also, from other studies, such sequences correlate with a high immunogenicity of the peptide. We conclude that there are structural features of peptides that change the stability of the class II molecule and that are independent of the "core" peptide seen by the T cells.     

Catalytic oxidation with Al-Ce-Fe-PILC as a post-treatment system for coffee wet processing wastewater

The effluent from the anaerobic biological treatment of coffee wet processing wastewater (CWPW) contains a non-biodegradable compound that must be treated before it is discharged into a water source. In this paper, the wet hydrogen peroxide catalytic oxidation (WHPCO) process using Al-Ce-Fe-PILC catalysts was researched as a post-treatment system for CWPW and tested in a semi-batch reactor at atmospheric pressure and 25 °C. The Al-Ce-Fe-PILC achieved a high conversion rate of total phenolic compounds (70%) and mineralization to CO(2) (50%) after 5 h reaction time. The chemical oxygen demand (COD) of coffee processing wastewater after wet hydrogen peroxide catalytic oxidation was reduced in 66%. The combination of the two treatment methods, biological (developed by Cenicafé) and catalytic oxidation with Al-Ce-Fe-PILC, achieved a 97% reduction of COD in CWPW. Therefore, the WHPCO using Al-Ce-Fe-PILC catalysts is a viable alternative for the post-treatment of coffee processing wastewater.     

Ethics of the distribution of health care

While the concept of a "right to health care" has been evolving in the United States, this should be distinguished from "the right to health," guaranteed in the constitutions of many socialist countries. In an effort to promote "quality of life" for their citizens, governments can, and do provide health care, but this does not always lead to health. In so doing, governments open access to care for those previously underserved--or unserved. For the United States at this time the goal becomes one of assuring equity, which will likely be achieved by locally based private and/or governmental entities, federated for greater efficiency and regulated by federal and state governments. Such programs will be staffed by a new breed of physician, the medical student of today.     

Resistive transition in superconducting films

The consequences of a vortex unbinding picture of two-dimensional superconductivity are worked out. Although there is no true finite-temperature phase transition, dirty superconducting films should display anomalous behavior below the BCS transition temperature and above an effective Kosterlitz-Thouless vortex unbinding temperature. In particular, both the conductivity and fluctuation diamagnetism behave like ₊ ² in this regime, where ₊ is the correlation length calculated by Kosterlitz, _{+ c} exp (B/T – T _c)^1/2. We estimate _c, B, and the vortex unbinding temperature, and determine the nonlinear resistivity below T _c. A recent theory of vortex dynamics, together with a time-dependent Ginzburg-Landau theory, lead to a determination of the frequency-dependent conductivity.This work was supported by the National Science Foundation under Grant No. DMR 77-10210.     

Grounding power systems above 600 V

The multigrounded neutral system for power systems above 600 V is a reasonable and safe design. The multigrounded neutral system provides 1) safety, 2) low zero sequence impedance than the single-point grounded neutral system, 3) lightning-arrester sizes can be optimized, 4) freezing and arctic conditions have an adverse impact on the zero sequence impedance, 5) cost of equipment for the multigrounded system is lower.     

Learning Dextrous Manipulation Skills for Multifingered Robot Hands Using the Evolution Strategy

We present a method for autonomous learning of dextrous manipulation skills with multifingered robot hands. We use heuristics derived from observations made on human hands to reduce the degrees of freedom of the task and make learning tractable. Our approach consists of learning and storing a few basic manipulation primitives for a few prototypical objects and then using an associative memory to obtain the required parameters for new objects and/or manipulations. The parameter space of the robot is searched using a modified version of the evolution strategy, which is robust to the noise normally present in real-world complex robotic tasks. Given the difficulty of modeling and simulating accurately the interactions of multiple fingers and an object, and to ensure that the learned skills are applicable in the real world, our system does not rely on simulation; all the experimentation is performed by a physical robot, in this case the 16-degree-of-freedom Utah/MIT hand. Experimental results show that accurate dextrous manipulation skills can be learned by the robot in a short period of time. We also show the application of the learned primitives to perform an assembly task and how the primitives generalize to objects that are different from those used during the learning phase.