全文获取类型
收费全文 | 3472篇 |
免费 | 234篇 |
国内免费 | 3篇 |
专业分类
电工技术 | 19篇 |
综合类 | 6篇 |
化学工业 | 949篇 |
金属工艺 | 39篇 |
机械仪表 | 49篇 |
建筑科学 | 206篇 |
矿业工程 | 3篇 |
能源动力 | 55篇 |
轻工业 | 589篇 |
水利工程 | 36篇 |
石油天然气 | 18篇 |
无线电 | 139篇 |
一般工业技术 | 517篇 |
冶金工业 | 622篇 |
原子能技术 | 9篇 |
自动化技术 | 453篇 |
出版年
2023年 | 26篇 |
2022年 | 85篇 |
2021年 | 131篇 |
2020年 | 56篇 |
2019年 | 87篇 |
2018年 | 95篇 |
2017年 | 84篇 |
2016年 | 114篇 |
2015年 | 85篇 |
2014年 | 153篇 |
2013年 | 221篇 |
2012年 | 184篇 |
2011年 | 266篇 |
2010年 | 179篇 |
2009年 | 153篇 |
2008年 | 183篇 |
2007年 | 154篇 |
2006年 | 168篇 |
2005年 | 104篇 |
2004年 | 119篇 |
2003年 | 100篇 |
2002年 | 84篇 |
2001年 | 57篇 |
2000年 | 57篇 |
1999年 | 49篇 |
1998年 | 44篇 |
1997年 | 44篇 |
1996年 | 51篇 |
1995年 | 43篇 |
1994年 | 37篇 |
1993年 | 33篇 |
1992年 | 40篇 |
1991年 | 36篇 |
1990年 | 47篇 |
1989年 | 32篇 |
1988年 | 35篇 |
1987年 | 29篇 |
1986年 | 22篇 |
1985年 | 22篇 |
1984年 | 31篇 |
1983年 | 12篇 |
1982年 | 24篇 |
1980年 | 15篇 |
1979年 | 23篇 |
1978年 | 13篇 |
1977年 | 8篇 |
1975年 | 13篇 |
1974年 | 6篇 |
1971年 | 6篇 |
1969年 | 6篇 |
排序方式: 共有3709条查询结果,搜索用时 15 毫秒
91.
Jørgensen MB Faber A Jespersen T Hansen K Ektor-Andersen J Hansen JV Holtermann A Søgaard K 《Ergonomics》2012,55(7):762-772
This study evaluates the implementation of physical coordination training (PCT) and cognitive behavioural training (CBTr) interventions in a randomised controlled trial at nine cleaners' workplaces. Female cleaners (n = 294) were randomised into a PCT, a CBTr or a reference (REF) group. Both 12-week interventions were performed in groups guided by an instructor. Records were kept on intervention dose (adherence) unanticipated events at the work place (context) and quality of intervention delivery (fidelity). Participant adherence was 37% in the PCT and 49% in the CBTr interventions. Optimal implementation was reached by only 6% in PCT and 42% in the CBTr. Analysis of the barriers to successful implementation indicated that the intervention process is sensitive to unanticipated events. In order to succeed in improving the health of high-risk populations such as cleaners and to correctly interpret intervention effects, more research on implementation is needed. Trial registration: ISRCTN96241850. PRACTITIONER SUMMARY: Both physical coordination training and cognitive behavioural training are potential effective workplace interventions among low educated job groups with high physical work demands. However, thorough consideration should be given to feasibility in the design of interventions. The optimal intervention should be tailored to closely match the implementation context and be robust and flexible to minimise susceptibility to changes in work organisation. 相似文献
92.
Liu Grace T.; Ferguson Adam R.; Crown Eric D.; Bopp Anne C.; Miranda Rajesh C.; Grau James W. 《Canadian Metallurgical Quarterly》2005,119(2):538
Following spinal transection of the upper thoracic spinal cord, male Sprague-Dawley rats given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed position. The region of the cord that mediates this instrumental learning was isolated using neuroanatomical tracing, localized infusion of lidocaine, and surgical transections. DiI and Fluoro-Gold microinjection at the site of shock application labeled motor neuron bodies of lamina IX in the lower lumbar region. Local application of the Na++ channel blocker lidocaine disrupted learning when it was applied over a region extending from the lower lumbar (L3) to upper sacral (S2) cord. The drug had no effect rostral or caudal to this region. Surgical transections as low as L4 had no effect on learning. Learning also survived a dual transection at L4 and S3, but not L4 and S2. The results suggest that the essential neural circuit lies between L4 and S3. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
93.
Nicole Altvater-Mackensen Gregor Balicki Lucie Bestakowa Bianca Bocatius Johannes Braun Lars Brehmer Verena Brune Kirstina Eigemeier F&#;sun Erdem Ralf Fritscher Anne Jacobs Bernd Klingsporn Marcin Kosinski Julia Kuntze Ju-Ra Lee Anna Osterhage Martin Probost Thorsten Risch Tobias Schmitt Wolfgang G. Stock Anja Sturm Katrin Weller Kerstin Werner 《Scientometrics》2005,63(3):463-529
Summary We operationalize scientific output in a region by means of the number of articles (as in the SciSearch database) per year and technology output by means of the number of patent applications (as in the database of the European Patent Office) per priority year. All informetric analyses were done using the DIALOG online-system. The main research questions are the following: Which scientific and technological fields or topics are most influent within a region and which institutions or companies are mainly publishing articles or holding patents? Do the distributions of regional science and technology fields and of publishing institutions follow the well-known informetric function? Are there - as it is expected - only few fields and few institutions which dominate the region? Is there a connection between the economic power of a region and the regional publication and patent output? Examples studied in detail are seven German regions: Aachen, Düsseldorf, Hamburg, Köln (Cologne), Leipzig - Halle - Dessau, München (Munich), and Stuttgart. Three different indicators were used, science and technology attraction of a region (number of scientific articles and patents), science and technology intensity (articles and patents per 1,000 inhabitants), and science and technology density (articles and patents per 1 billion EURO gross value added). Top region concerning both attraction and intensity is Munich, concerning density it is Aachen. 相似文献
94.
Andronescu Mirela Dees Danielle Slaybaugh Laura Zhao Yinglei Condon Anne Cohen Barry Skiena Steven 《Natural computing》2003,2(4):391-415
We present an efficient algorithm for determining whether all moleculesin a combinatorial set of DNA or RNA strandsare structure free, and thus availablefor bonding to their Watson-Crick
complements.This work is motivated by the goalof testing whether strands used in DNAcomputations or as molecular bar-codesare
structure free, where the strands areconcatenations of short words. We alsopresent an algorithm for determining whetherall
words in S*, for some finite setS of equi-length words, are structure free.
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
95.
This article provides an overview of the factors that may contribute to the effective term of protection for a pharmaceutical product in the USA––by patent and by FDA market exclusivities, identifies public and commercial sources for collecting relevant patent term and exclusivity data, and provides a strategy for ensuring that the effective term of protection has been calculated accurately. 相似文献
96.
E. J. O'Brien, M. L. Rizzella, J. E. Albrecht, and J. G. Halleran (1998) demonstrated that, consistent with the memory-based text processing view, outdated or incorrect information can be reactivated through a passive resonance process. Once reactivated, this outdated information can still influence comprehension. R. A. Zwaan and C. J. Madden (2004) suggested that the O'Brien et al. findings resulted from problems with the materials used. The present authors show that the possible "problems" identified by Zwaan and Madden do not adequately explain the findings of O'Brien et al. and that Zwaan and Madden's Experiment 3 lacks sufficient control or power to support their alternative interpretation of O'Brien et al. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
97.
Anne Benoit Fanny Dufossé Alain Girault Yves Robert 《Journal of Parallel and Distributed Computing》2013
We consider pipelined real-time systems that consist of a chain of tasks executing on a distributed platform. The processing of the tasks is pipelined: each processor executes only one interval of consecutive tasks. We are interested in minimizing both the input–output latency and the period of application mapping. For dependability reasons, we are also interested in maximizing the reliability of the system. We therefore assign several processors to each interval of tasks, so as to increase the reliability of the system. Both processors and communication links are unreliable and subject to transient failures. We assume that the arrival of the failures follows a constant parameter Poisson law, and that the failures are statistically independent events. We study several variants of this multiprocessor mapping problem, with several hypotheses on the target platform (homogeneous/heterogeneous speeds and/or failure rates). We provide NP-hardness complexity results, and optimal mapping algorithms for polynomial problem instances. Efficient heuristics are presented to solve the general case, and experimental results are provided. 相似文献
98.
Peter Chemweno Liliane Pintelon Anne‐Marie De Meyer Peter N. Muchiri Adriaan Van Horenbeek James Wakiru 《Quality and Reliability Engineering International》2017,33(3):551-564
The failure mode and effect analysis (FMEA) is a widely applied technique for prioritizing equipment failures in the maintenance decision‐making domain. Recent improvements on the FMEA have largely focussed on addressing the shortcomings of the conventional FMEA of which the risk priority number is incorporated as a measure for prioritizing failure modes. In this regard, considerable research effort has been directed towards addressing uncertainties associated with the risk priority number metrics, that is occurrence, severity and detection. Despite these improvements, assigning these metrics remains largely subjective and mostly relies on expert elicitations, more so in instances where empirical data are sparse. Moreover, the FMEA results remain static and are seldom updated with the availability of new failure information. In this paper, a dynamic risk assessment methodology is proposed and based on the hierarchical Bayes theory. In the methodology, posterior distribution functions are derived for risk metrics associated with equipment failure of which the posterior function combines both prior functions elicited from experts and observed evidences based on empirical data. Thereafter, the posterior functions are incorporated as input to a Monte Carlo simulation model from which the expected cost of failure is generated and failure modes prioritized on this basis. A decision scheme for selecting appropriate maintenance strategy is proposed, and its applicability is demonstrated in the case study of thermal power plant equipment failures. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
99.
Marie-Christine Lebart Franoise Trousse Gilles Valette Joan Torrent Morgane Denus Nadine Mestre-Frances Anne Marcilhac 《International journal of molecular sciences》2022,23(15)
Reg-1α/lithostathine, a protein mainly associated with the digestive system, was previously shown to be overexpressed in the pre-clinical stages of Alzheimer’s disease. In vitro, the glycosylated protein was reported to form fibrils at physiological pH following the proteolytic action of trypsin. However, the nature of the protease able to act in the central nervous system is unknown. In the present study, we showed that Reg-1α can be cleaved in vitro by calpain-2, the calcium activated neutral protease, overexpressed in neurodegenerative diseases. Using chemical crosslinking experiments, we found that the two proteins can interact with each other. Identification of the cleavage site using mass spectrometry, between Gln4 and Thr5, was found in agreement with the in silico prediction of the calpain cleavage site, in a position different from the one reported for trypsin, i.e., Arg11-Ile12 peptide bond. We showed that the cleavage was impeded by the presence of the neighboring glycosylation of Thr5. Moreover, in vitro studies using electron microscopy showed that calpain-cleaved protein does not form fibrils as observed after trypsin cleavage. Collectively, our results show that calpain-2 cleaves Reg-1α in vitro, and that this action is not associated with fibril formation. 相似文献
100.
Katie L. J. Cederberg Umaer Hanif Vicente Peris Sempere Julien Hdou Eileen B. Leary Logan D. Schneider Ling Lin Jing Zhang Anne M. Morse Adam Blackman Paula K. Schweitzer Suresh Kotagal Richard Bogan Clete A. Kushida Yo-El S. Ju Nayia Petousi Chris D. Turnbull Emmanuel Mignot The STAGES Cohort Investigator Group 《International journal of molecular sciences》2022,23(14)
Obstructive sleep apnea (OSA), a disease associated with excessive sleepiness and increased cardiovascular risk, affects an estimated 1 billion people worldwide. The present study examined proteomic biomarkers indicative of presence, severity, and treatment response in OSA. Participants (n = 1391) of the Stanford Technology Analytics and Genomics in Sleep study had blood collected and completed an overnight polysomnography for scoring the apnea–hypopnea index (AHI). A highly multiplexed aptamer-based array (SomaScan) was used to quantify 5000 proteins in all plasma samples. Two separate intervention-based cohorts with sleep apnea (n = 41) provided samples pre- and post-continuous/positive airway pressure (CPAP/PAP). Multivariate analyses identified 84 proteins (47 positively, 37 negatively) associated with AHI after correction for multiple testing. Of the top 15 features from a machine learning classifier for AHI ≥ 15 vs. AHI < 15 (Area Under the Curve (AUC) = 0.74), 8 were significant markers of both AHI and OSA from multivariate analyses. Exploration of pre- and post-intervention analysis identified 5 of the 84 proteins to be significantly decreased following CPAP/PAP treatment, with pathways involving endothelial function, blood coagulation, and inflammatory response. The present study identified PAI-1, tPA, and sE-Selectin as key biomarkers and suggests that endothelial dysfunction and increased coagulopathy are important consequences of OSA, which may explain the association with cardiovascular disease and stroke. 相似文献