<Emphasis FontCategory="SansSerif">LRE</Emphasis>-<Emphasis FontCategory="SansSerif">TL</Emphasis>: an optimal multiprocessor algorithm for sporadic task sets with unconstrained deadlines

This article presents a detailed discussion of LRE-TL (Local Remaining Execution-TL-plane), an algorithm that schedules hard real-time periodic and sporadic task sets with unconstrained deadlines on identical multiprocessors. The algorithm builds upon important concepts such as the TL-plane construct used in the development of the LLREF algorithm (Largest Local Remaining Execution First). This article identifies the fundamental TL-plane scheduling principles used in the construction of LLREF . These simple principles are examined, identifying methods of simplifying the algorithm and allowing it to handle a more general task model. For example, we identify the principle that total local utilization can never increase within any TL-plane as long as a minimal number of tasks are executing. This observation leads to a straightforward approach for scheduling task arrivals within a TL-plane. In this manner LRE-TL can schedule sporadic tasks and tasks with unconstrained deadlines. Like LLREF, the LRE-TL scheduling algorithm is optimal for task sets with implicit deadlines. In addition, LRE-TL can schedule task sets with unconstrained deadlines provided they satisfy the density test for multiprocessor systems. While LLREF has a O(n ²) runtime per TL-plane, LRE-TL’s runtime is O(nlog n) per TL-plane.     

Exploring schema-driven differences in situation awareness between road users: an on-road study of driver,cyclist and motorcyclist situation awareness

Collisions between different road users make a substantial contribution to road trauma. Although evidence suggests that different road users interpret the same road situations differently, it is not clear how road users' situation awareness differs, nor is it clear which differences might lead to conflicts. This article presents the findings from an on-road study conducted to examine driver, motorcyclist and cyclist situation awareness in different road environments. The findings suggest that, in addition to minor differences in the structure of different road users' situation awareness (i.e. amount of information and how it is integrated), the actual content of situation awareness in terms of road user schemata, the resulting interaction with the world and the information underpinning situation awareness is markedly different. Further examination indicates that the differences are likely to be compatible along arterial roads, shopping strips and at roundabouts, but that they may create conflicts between different road users at intersections. Interventions designed to support compatible situation awareness and behaviour between different road users are discussed.     

Eleostearic acid derivatives. I. Reactions at the carboxyl group

Nine C₁ substituted derivatives of eleostearic acid have been prepared and characterized by elemental analyses and spectrophotometric data. The preparation of two additional derivatives is indicated by infrared spectroscopy, but difficulties in purification precluded elemental analysis data. Comments are made concerning conditions for product stability and reaction environment.     

The effects of sleep loss on component movements of human motion.

Does sleep loss produce differential effects on component movements of motion? Without a control group, 19 college students were given "several special tests of perceptual and motor functions in a 5-day training period, in a 3-day sleep loss period, and in a 2-day recovery period." Manipulation and travel movements in a panel-control task, speed of performance in a test of bimanual and unimanual coordination, speed of discrete leg movements, and critical flicker frequency all decreased. Contacts in a test of hand steadiness showed irregular change. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Action of cholecystokinin and cholinergic agents on membrane-bound calcium in dispersed pancreatic acinar cells

In dispersed acinar cells prepared from guinea pig pancreas, cellular uptake of 45Ca was moderately rapid and reached a steady state by 60 min. At the steady state, 69% of total cellular 45Ca was membrane-bound. In acinar cells preloaded with 45Ca and then incubated with COOH-terminal octapeptide of cholecystokinin (CCK-OP) or carbamylcholine, total cellular 45Ca decreased by approximately 40% within 5-10 min and then steadily increased to control values by 60 min. Under identical conditions, membrane-bound 45Ca decreased by 40% within 5-10 min and remained constant for the duration of the incubation. Free cellular 45Ca did not change during the initial 30 min but then increased steadily to values three times those in control cells by 60 min. In cells preloaded with 45Ca and then incubated with EDTA, the loss of total cellular radioactivity stimulated by CCK-OP could be accounted for by loss of membrane-bound 45Ca. CCK-OP failed to alter total cellular uptake of 45Ca when both tracer and peptide were added at the beginning of the incubation. Under identical conditions, membrane-bound 45Ca was not altered by CCK-OP during the first 30 min of incubation but was significantly below control values after this time. The effect of CCK-OP on free cellular 45Ca was the same as in cells preloaded with the tracer. These results suggest that CCK-OP causes release of 45Ca from a membrane-bound compartment that equilibrates slowly with extracellular fluid and that the change in free cellular 45Ca is a secondary effect.     

Solution-phase deposition and nanopatterning of GeSbSe phase-change materials

Chalcogenide films with reversible amorphous-crystalline phase transitions have been commercialized as optically rewritable data-storage media, and intensive effort is now focused on integrating them into electrically addressed non-volatile memory devices (phase-change random-access memory or PCRAM). Although optical data storage is accomplished by laser-induced heating of continuous films, electronic memory requires integration of discrete nanoscale phase-change material features with read/write electronics. Currently, phase-change films are most commonly deposited by sputter deposition, and patterned by conventional lithography. Metal chalcogenide films for transistor applications have recently been deposited by a low-temperature, solution-phase route. Here, we extend this methodology to prepare thin films and nanostructures of GeSbSe phase-change materials. We report the ready tuneability of phase-change properties in GeSbSe films through composition variation achieved by combining novel precursors in solution. Rapid, submicrosecond phase switching is observed by laser-pulse annealing. We also demonstrate that prepatterned holes can be filled to fabricate phase-change nanostructures from hundreds down to tens of nanometres in size, offering enhanced flexibility in fabricating PCRAM devices with reduced current requirements.     

Properties of Lead Fluorosilicate Glasses

Lead fluorosilicate glasses containing up to 25 mol% PbF₂ were prepared. The dc electrical conductivity, thermal expansion, and transformation-range viscosity of these glasses indicate that they are anionic conductors and that fluorine significantly decreases the continuity of the vitreous network.     

Synthesis and characterization of pendent hydroxy fluoroesters of secondary high molecular weight guayule rubber

The epoxidation of secondary high molecular weight guayule rubber (SHMWGR) and subsequent ring opening with fluoroacids to give hydroxyfluoroesters (FGR) is reported. Structural characterization was performed with FTIR; ¹H-, ¹³C-, and ¹⁹F-NMR; and DSC. The percent epoxidation was quantitatively determined by ¹H-NMR. It was noted that the glass transition temperatures (T_g) of the FGR polymers increased with increasing fluoro acid content; however, reactions with longer chain, highly fluorinated acids lowered the T_g. © 1997 John Wiley & Sons, Inc. J Appl Polym Sci 63: 1077–1089, 1997     

Challenges in Biomaterial-Based Drug Delivery Approach for the Treatment of Neurodegenerative Diseases: Opportunities for Extracellular Vesicles

Biomaterials have been the subject of numerous studies to pursue potential therapeutic interventions for a wide variety of disorders and diseases. The physical and chemical properties of various materials have been explored to develop natural, synthetic, or semi-synthetic materials with distinct advantages for use as drug delivery systems for the central nervous system (CNS) and non-CNS diseases. In this review, an overview of popular biomaterials as drug delivery systems for neurogenerative diseases is provided, balancing the potential and challenges associated with the CNS drug delivery. As an effective drug delivery system, desired properties of biomaterials are discussed, addressing the persistent challenges such as targeted drug delivery, stimuli responsiveness, and controlled drug release in vivo. Finally, we discuss the prospects and limitations of incorporating extracellular vesicles (EVs) as a drug delivery system and their use for biocompatible, stable, and targeted delivery with limited immunogenicity, as well as their ability to be delivered via a non-invasive approach for the treatment of neurodegenerative diseases.     

Effects of morphology on the micro-compression response of carbon nanotube forests

This study reports the mechanical response of distinct carbon nanotube (CNT) morphologies as revealed by flat punch in situ nanoindentation in a scanning electron microscope. We find that the location of incipient deformation varies significantly by changing the CNT growth parameters. The initial buckles formed close to the growth substrate in 70 and 190 μm tall CNT forests grown with low pressure chemical vapor deposition (LPCVD) and moved to ～100 μm above the growth substrate when the height increased to 280 μm. Change of the recipe from LPCVD to CVD at pressures near atmospheric changed the location of the initial buckling event from the bottom half to the top half of the CNT forest. Plasma pretreatment of the catalyst also resulted in a unique CNT forest morphology in which deformation started by bending and buckling of the CNT tips. We find that the vertical gradients in CNT morphology dictate the location of incipient buckling. These new insights are critical in the design of CNT forests for a variety of applications where mechanical contact is important.