Method for monitoring positions in three dimensions

This article presents a fundamentally new method for controlling the position of an object in three-dimensional space by using a microinterferometer. This method assures high accuracy and efficiency. The method can be used for verifying accuracy of contact gauges in position-measuring machinery. Translated from Izmeritel'naya Tekhnika, No. 4, pp. 17–18, April, 1996.     

Effect of naftidrofuryl (LS129) on axonal growth

Wistar rats, eight days old, were subjected to permanent bilateral forebrain ischemia, followed by hypoxia for 15 minutes. A cerebral infarct, mainly involving the cerebral neocortex, hippocampus, amygdala, striatum and subcortical white matter was produced. Neurons and glia showing punctate chromatin condensation and karyorrhectic cells were observed 12 hours after hypoxia-ischemia. Their number increased during the first two days and recruitment of cells with degenerating nuclei occurred until day five. In situ labeling of nuclear DNA fragmentation stained many normal-appearing nuclei, as well as punctate chromatin condensations and nuclear fragments in karyorrhectic cells. Delayed neuronal death in the CA1 area of the hippocampus was observed after 20 minutes of transient forebrain ischemia in the adult gerbil. In situ labeling of nuclear DNA fragmentation demonstrated stained punctate chromatin condensation in a few degenerating cells at 48 hours post-ischemia. Substantial labeling of CA1 neurons occurred in the fourth day. Agarose gel electrophoresis of extracted brain DNA from ischemic infant rats and adult gerbils showed a ladder-type pattern which is typical of nuclear DNA fragmentation into oligonucleosomal fragments (internucleosomal cleavage). These findings suggest that endonuclease(s) activation may play a role in cell death induced by different forms of hypoxia-ischemia.     

A unique property of a plasma proteoglycan, the C1q inhibitor. An anticoagulant state resulting from its binding to fibrinogen

The C1q inhibitor, C1qI, an approximately 30-kD circulating chondroitin-4 sulfate proteoglycan, displayed concentration-dependent prolongation of plasma and fibrinogen solution clotting times. Under factor XIIIa catalyzed cross-linking conditions and maximum C1qI concentrations, minor amounts of clot formed displaying complete gamma-gamma dimer formation but virtually no alpha-polymer formation. The anticoagulant effect was undiminished by its binding to C1q, by increased ionic strength, and by CaCl2, but was abolished by incubation of C1qI with chondroitinase ABC. 125I-labeled C1qI bound to immobilized fibrinogen, fibrin monomer, fibrinogen plasmic fragments D1 and E, and fibrin polymers. Occupancy on the E domain required uncleaved fibrinopeptides together with another structure(s), and it did not decrease binding of thrombin to fibrinogen. Occupancy on the D domain did not decrease the fibrinogen binding to fibrin monomer. We conclude that the E domain occupancy impaired fibrinopeptide cleavage, and occupancy on the D domain impaired polymerization, both steric hindrance effects. C1qI binding to fibrinogen explains at least in part the well-known fibrin(ogen) presence in immune complex-related lesions, and the fibrinogen presence in vascular basement membranes and atheromata. We postulate that fibrin binding by resident basement membrane proteoglycans provides dense anchoring of thrombus, substantially enhancing its hemostatic function.     

Charge-based capacitance measurements (CBCM) on MOS devices

A new simple method of measuring capacitance-voltage characteristics of MOS devices is presented. Proceeding from the charge-based capacitance measurement technique suggested recently, a compact test structure with high resolution has been developed, which only requires measurement of do quantities. The method was tested on a 0.6-μm CMOS process with small and large area capacitors and compared to well-known high-frequency capacitance-voltage results. Beside using a reference structure, a second means of extracting parasitic effects is demonstrated for small structures. The test structure allows measurements in a wide frequency range with high accuracy and low noise contribution at small capacitance levels     

Influence of body segment dynamics on loads at the lumbar spine during lifting.

Flexion-extension moments acting at the L5/S1 level and hip joints were calculated using three different techniques; a pure static analysis, a static analysis including the inertial force of the load, and a dynamic analysis. Ten subjects participated in the study and were asked to lift a box weighing either 50 N or 150 N, using a freestyle technique. The lifts were performed at normal and fast speed. The intra-subject lifting techniques were consistent when lifting the same loads. The moments predicted by the dynamic analysis and the static analysis were the same when holding weights in static postures. When performing the lifts, differences in the peak moments occurred between static and dynamic analyses. These differences were influenced by external load and by lifting speed. Taking the effect of the inertia of load into account in the static analysis resulted in an increase in the moment magnitude, but the predicted moment was still much less than in the dynamic analysis which yielded the largest moment magnitudes. The difference between dynamic and static analysis was greatest when lifting 50 N at fast speed; an 87% increase in L5/S1 moment and a 95% increase in hip moment was observed when replacing the pure static with a dynamic analysis.     

Queueing analyses of traffic access control strategies withpreemptive and nonpreemptive disciplines in wideband integrated networks

A multiserver queueing model of access control strategies for a wideband integrated services digital network (ISDN) is considered. There are two types of service requests (SRs): Type 1 SR requires b servers (basic bandwidth units, BBUs) of the c available servers, while Type 2 SR requires a single server. Both types of SRs are queuable in two separate infinite-size buffers. A Type 1 SR is allowed to seize d(⩽b) servers at first and then acquire additional servers as they become available to meet the original requirement of b servers. The arrival processes of both types of SRs are Poisson and the service times are exponentially distributed with mean b/dμ₁ and 1/μ₂ for Type 1 SR and Type 2 SR, respectively. Preemptive and nonpreemptive priority disciplines with movable boundary are analyzed using the Neuts' matrix-analytic approach. Numerical examples of the queue length distribution and the mean waiting time of the SRs are presented     

Organized media for fluorescence analysis of complex samples: comparison of bile salt and conventional detergent micelles in coal liquids.

Accurate quantitative determinations are often difficult to obtain from fluorescence analysis of complex samples due to sample matrix effects and intermolecular interactions between solutes. Organized media can be used to minimize these unwanted processes without physical separation or extraction of the analytes from the sample matrix by isolating the analyte molecules in a uniform microenvironment within the sample. The advantages of bile salt micellar media over conventional detergent micelles are demonstrated for analysis of coal liquids. The bile salt media is shown to increase the sensitivity and dynamic range of fluorescence measurements relative to simple ethanolic solutions, without promoting gound-state and excited-state interactions that occur in the detergent micellar media.     

Phonons and spin excitations in the extended t-J model

We consider the effects of spin-phonon coupling within the slave-boson mean-field treatment of the extended t-J model. With no additional assumptions the theory is found to give a semi-quantitative account of the frequency and linewidth anomalies observed for certain phonon modes in Y Ba₂Cu₃O₇ at the superconducting transition. We report also investigations of the role of this coupling in affecting thermodynamic properties and spin dynamics.     

Performance analysis of a class of transient detection algorithms-aunified framework

The detection of short-duration nonstationary signals, which are commonly referred to as transients, is often performed in the time-frequency-transform domain. An analytical framework within which the performance of different detectors based on linear transforms can be easily compared, for different classes of signals, is developed. A given class of transients is modeled as a signal existing in a linear subspace, plus a mismatch signal. Closed-form expressions are derived for the best and the worst detection performance for all possible transients in a given class. Using this framework, the performance of detectors based on the Gabor transform and on the short-time Fourier transform is evaluated and compared     

Nonlinear magnetic field calculation using dipole approximation

A program for calculating static magnetic fields using an integral method for the iron contribution to the field is presented. To calculate the magnetic coefficients one essentially uses a simple dipole approximation. The developed formalism is applied to compute the magnetic field of toroidally shaped iron geometries. Using this formalism a program tractable on microcomputers was written with a discretization of the iron in up to 1600 elements. The results agree well with those obtained with the program TOSCA