THC-induced place and taste aversions in Lewis and Sprague-Dawley rats.

The hedonic properties of delta-9-tetrahydrocannabinol (THC) were assessed in place and taste conditioning paradigms in both Lewis and Sprague-Dawley rat strains. THC produced place avoidance, taste avoidance, and aversive taste reactivity responses in both strains. The Lewis strain displayed more aversive taste reactions and a stronger taste avoidance when conditioned with lower doses of THC than did the Sprague-Dawley strain of rats. THC is an anomalous drug of abuse that appears to be aversive to rats when assessed by these measures. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Access to hypertensive care. Effects of income, insurance, and source of care

BACKGROUND: This study examines the relationship between income, health insurance, and usual source of care characteristics and screening and management of hypertension. METHODS: This is a secondary analysis of data from the 1987 National Medical Expenditure Survey. Adult survey respondents constitute a sample representative of the total adult noninstitutionalized US population. Screening, follow-up care, and pharmacologic treatment for hypertension were examined among low income individuals, the uninsured, those without a usual source of care place, and those without a particular usual source of care physician. RESULTS: The uninsured, individuals without a usual source of care place, and those without a particular usual source of care physician received less screening, follow-up care, and pharmacologic treatment for hypertension. Income did not affect receipt of hypertensive care. CONCLUSIONS: Lack of health insurance and lack of a usual source of care are barriers to hypertensive care. Policies that increase access to health insurance or to usual source of care physicians may enable more individuals to attain control of hypertension.     

Ambient, biological, and biological effect monitoring of exposure to polycyclic aromatic hydrocarbons (PAHs)

A novel strategy was utilised to assess the risk to health from exposure to polycyclic aromatic hydrocarbons (PAHs). Ambient monitoring was carried out by personal sampling. Urinary thioethers (UTh) and urinary 1-hydroxypyrene (1-HP) were utilised for biological monitoring. Urinary d-glucaric acid (UDGA) and sister chromatid exchange (SCE) in peripheral blood lymphocytes were used as biological effect markers. The population was categorised into exposed and control groups according to the external dose of PAHs. The excretion of 1-HP in the controls over the 3-day period showed a relatively stable baseline, while the exposed showed a significant increase over the same period of time. SCE frequency in the exposed population was significantly different from controls.     

基于多分辨率的图象压缩系统结构分析

本文着重对图象多分辨率技术进行分析，并提出了相应的系统结构成框架，同时还探讨了以图象多分辨率处理为核心，采用了 新的压缩编码的可能性。     

Intermediate-term outcome of cervical spinal cord-injured patients older than 50 years of age

STUDY DESIGN: This study retrospectively reviewed the intermediate-term clinical outcome of patients who were 50 years of age or older at the time they experienced their cervical spinal cord injury. OBJECTIVES: To establish reasonable expectations for the functional outcome in the older patient with cervical spinal cord injury. BACKGROUND DATA: The long-term morbidity and mortality of large groups of patients with spinal cord injury have been reported. The specific functional ability, disposition, morbidity, and mortality of this group of older patients injured after 50 years of age, however, have been less well defined. METHODS: Forty-one consecutive patients older than 50 years of age at the time of cervical cord injury were studied, and functional abilities, independence, need for assistance in activities of daily living, disposition, morbidity, and mortality were assessed. All patients had more than 2 years of follow-up examinations (mean, 5.5 years) by the same spine injury service. RESULTS: There were 13 complete and 28 incomplete cervical cord lesions. The mean age of the patients at follow-up examination was 67.5 years. The average follow-up period was 5.5 years after injury. None of the patients with complete cord injury improved, and all required extensive care. Twenty-one (80%) of 26 of the patients with incomplete cord injury were able to ambulate with some assistance. Nineteen of 26 patients had independent or near-independent abilities with activities of daily living. Twenty (77%) of 26 were able to return home. All patients with complete cord injury (13 of 13) had died by the time of the follow-up visit. Seventy-seven percent (10 of 13) of this patient group had died within the first year. Those surviving lived an average of 3.5 years after their injury. Fourteen of 28 patients with incomplete cord injury (50%) had died by the time of the follow-up visit. Six (43%) of the 14 deaths were attributed to complications of their spinal cord injury. CONCLUSION: The functional outcome of the person older than 50 years with a complete cervical cord injury is poor. Of the 14% who survived the first year, all required extensive attendant care, and no neurologic improvement was seen. The patient with an incomplete cord injury has an overall good outcome regarding ambulation and returning to home.     

COAEs and SSOAEs in adults with increased age

OBJECTIVE: The purpose of this study was to compare click-evoked otoacoustic emissions (COAEs) of subjects having similar auditory thresholds but different age ranges. It is well known that elevated hearing thresholds are common with increasing age and that deterioration of outer hair cells is often noted in cases of hearing loss due to increased age. It has also been reported that evoked otoacoustic emissions (EOAEs) decrease with increased age. However, there is still some question whether changes in EOAEs with aging are associated with the increased hearing threshold or whether there is some additional effect of aging that enfluences EOAEs. DESIGN: COAE input/output functions and synchronized spontaneous OAEs (SSOAEs) were measured in two groups of subjects having similar auditory thresholds, one ranging in age from 19 to 29 yr, the other ranging in age from 40 to 61 yr. Mixed-model ANOVAs were performed to determine whether there were any statistically significant differences in COAEs based on age group. RESULTS: There were no statistically significant differences in COAE level or COAE threshold between age groups. Significant differences in COAEs were found for subjects based on whether they had measurable SSOAEs, regardless of age. CONCLUSIONS: Age does not significantly reduce COAE level nor increase COAE threshold. Other factors, such as presence of SSOAEs and hearing loss, undoubtedly have more influence on COAEs than the factor of age.     

Dynamic digital holographic wavelength filtering

This paper describes the theory and results of a new generic technology for use in optical telecommunications and wavelength division multiplexing (WDM): dynamic digital holographic wavelength filtering. The enabling component is a polarization-insensitive ferroelectric liquid crystal (FLC) spatial light modulator (SLM) in conjunction with a highly wavelength-dispersive fixed diffractive element. The technology has been used to perform demultiplexing of single or multiple WDM signals, dynamic erbium doped fiber amplifier (EDFA) gain equalization and channel management, and used to tune an erbium-doped fiber laser (EDFL) functioning as a high power, very narrow linewidth WDM source