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71.
OBJECTIVE: The authors examined the efficacy of intramuscular flunitrazepam compared with intramuscular haloperidol for the immediate control of agitated or aggressive behavior in acutely psychotic patients. METHOD: Twenty-eight actively psychotic inpatients, aged 20-60 years, who were under treatment with neuroleptic agents were selected for the study. Each was randomly assigned on a double-blind basis to receive either 5 mg i.m. of haloperidol (N=13) or 1 mg i.m. of flunitrazepam (N=15) during an aggressive event. Verbal and physical aggression was measured over time with the Overt Aggression Scale. Patients were also rated with the Brief Psychiatric Rating Scale and the Clinical Global Impression scale. RESULTS: Both flunitrazepam and haloperidol exhibited acute antiaggressive activity. This beneficial effect, as assessed by the Overt Aggression Scale, was obtained within 30 minutes. CONCLUSIONS: Intramuscular flunitrazepam may serve as a convenient, rapid, safe, and effective adjunct to neuroleptics in reducing aggressive behavior in emergency psychiatric settings. 相似文献
72.
The effect of blanching on the retention of β-carotene and ascorbic acid, and non-enzymatic browning (NEB) during storage
of dehydrated carrot slices was studied. Blanched carrots contained higher β-carotene but lower ascorbic acid than their unblanched
counterpart just after drying, whereas NEB was unaffected by blanching. During storage of dehydrated carrots a decrease in
β-carotene and ascorbic acid content with an increase in NEB values was observed. Blanching was helpful in limiting the loss
of quality parameters irrespective of storage and packaging conditions.
Received: 22 May 2000 / Revised version: 11 October 2000 相似文献
73.
PURPOSE: To evaluate the efficacy of topical mitomycin C in treating conjunctival and corneal epithelial dysplasia and neoplasia. METHODS: Seven eyes of seven patients with conjunctival and corneal epithelial dysplasia and neoplasia were treated with one drop of topical mitomycin C 0.04% four times a day for 7 days in alternate weeks. The patients' charts were reviewed retrospectively. Patients with either multiple recurrences or extensive ocular surface involvement were treated. In all eyes, the diagnosis of epithelial dysplasia or neoplasia was confirmed by histopathology before the onset of therapy. Patients were examined at least every 14 days during treatment and examined at intervals after completion of treatment. RESULTS: With topical mitomycin C, six eyes of seven patients had complete clinical regression of their conjunctival and corneal epithelial dysplasia and neoplasia. One eye of one patient had partial clinical regression of conjunctival and corneal epithelial dysplasia. Follow-up after completion of topical mitomycin C therapy and excision of residual disease ranged from 2 to 16 months (mean, 9 months; SD, 4.3 months) and was without clinical sign of recurrence. Topical mitomycin C therapy was associated with transitory ocular discomfort, conjunctival injection, tearing, photophobia, and punctate epithelial keratopathy. CONCLUSION: In this small series of eyes, topical mitomycin C was effective as a treatment for conjunctival and corneal epithelial dysplasia and neoplasia. 相似文献
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76.
Devender S. Negi Felix Sobotka Tobias Kimmel Günter Wozny Reinhard Schomäcker 《Journal of the American Oil Chemists' Society》2007,84(1):83-90
The present work focused on the glycerolysis of fatty acid methyl esters. The aim was to develop and test a kinetic model
that could be used to reliably simulate different process alternatives for this reaction. A prerequisite was the identification
and characterization of the factors that affect the reaction kinetics. Experiments were carried out in a batch reactor with
and without forced removal of methanol, which is one of the reaction products. Concentrations of all components in the two-phase
system were measured. It was found that the methanol concentration has a strong effect on the reaction rate and equilibrium
conversion. Near-complete conversions were obtained by stripping methanol with an inert gas. The glycerol concentration in
the ester phase was found to increase as the reaction proceeds, which also accelerates the reaction. Effects of mass transfer
on the reaction rate were not found to control the reaction rate under well-agitated conditions. A semi-empirical model was
used to simulate the reaction. The results from the semi-empirical model show good agreement with experimental results. 相似文献
77.
Bal K Agrawal S Agrawal P S Yadav S Kumar J S Negi Namrata Varshney 《Bulletin of Materials Science》1991,14(4):967-971
In the series of the layered highT
c
superconductors (A)1,2 B2Ca
n−1Cu
n
O2n+3,4 (A=Tl or Bi;B=Ba or Sr), withn=number of consecutive Cu-O layers, the electron energy states of some of the Tl-based systems have been investigated. The
electron and phonon dispersion curves have been obtained. The electronic states near the Fermi level are dominated by the
hybridized Cu(d) and the O(p) orbitals. The dispersion curves are highly two-dimensional with very small dispersion alongc-axis. The number of bands is enhanced with increase in the number of the consecutive Cu-O planes (n). The present results agree with those obtained earlier for other superconducting phases. The phonons are overall dominated
by the vibrations of the light mass oxygen atom modes both lying in or outside the Cu-O planes. The low-frequency phonons
involve the motions of the heavier Tl, Ba atoms etc. 相似文献
78.
BS Glatt DB Sarwer DE O'Hara C Hamori LP Bucky D LaRossa 《Canadian Metallurgical Quarterly》1999,103(1):76-82; discussion 83-5
Reduction mammaplasty is performed typically to alleviate the painful physical symptoms of macromastia. Women who suffer from macromastia also frequently present to the plastic surgeon with heightened body image dissatisfaction and maladaptive behavioral changes in response to their breast size. Numerous investigations have demonstrated improvement in physical symptoms after breast reduction surgery. Studies have also suggested that psychological improvement occurs postoperatively; however, they have not used well-validated, standardized psychological measures. The present study is a retrospective analysis of the physical and psychological status of women who underwent reduction mammaplasty. One hundred ten patients who underwent a reduction mammaplasty between 1982 and 1996 were mailed a packet of questionnaires designed to assess current physical symptoms and body image. Sixty-one of the 110 patients (55 percent) responded. The vast majority reported substantial improvement or elimination of neck, back, shoulder, and breast pain, grooving from bra straps, poor posture, skin irritation, and social embarrassment. In addition, they reported significantly less dissatisfaction with their breasts as compared with a sample of breast reduction patients assessed preoperatively. Symptom relief and improved body image occurred independently of preoperative body weight, as we found few significant differences between obese and non-obese women concerning the resolution of physical symptoms or improvement in body image. Results provide further evidence of the efficacy of reduction mammaplasty not only for relief of physical symptoms but also for alleviation of body image dissatisfaction. 相似文献
79.
BS Iyengar RT Dorr DS Alberts EM Hersh SE Salmon WA Remers 《Canadian Metallurgical Quarterly》1999,42(3):510-514
A set of 20 2-cyanoaziridine-1-carboxamides was synthesized from 2-cyanoaziridine and appropriate isocyanates. These compounds were active against a variety of solid and hematological tumor cells in culture, including strains resistant to doxorubicin and mitoxantrone. Their potencies in these assays correlated with the lipophilicity of substituents. The N-phenyl derivative was more potent and equally effective to imexon, a cyclized 2-cyanoaziridine-1-carboxamide of clinical interest, against cloned fresh human tumors. 相似文献
80.