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101.
Lars Nolle Alec Goodyear Adrian A. Hopgood Phil D. Picton Nicholas ST. J. Braithwaite 《工程优选》2013,45(5):463-477
In a previous investigation, a simulated annealing (SA) method was developed to optimize 14 Fourier terms in a radio-frequency waveform for active compensation of a Langmuir probe system. This approach was shown to find better solutions in less time than skilled human operators. However, variations in fitness indicated that the SA algorithm did not always find the precise global solution, although it came consistently close to it. This variability was caused by the limited number of fitness evaluations available due to time constraints. In this research, the chosen maximum step width has been shown to have a significant effect on the overall performance of the algorithm. A scaling function has been developed to adapt the maximum step width of the SA algorithm, on-line, as a function of the number of elapsed iterations. The modified algorithm has been shown to find fitter solutions with reduced variability in fitness. 相似文献
102.
Washburn ST Bingman TS Braithwaite SK Buck RC Buxton LW Clewell HJ Haroun LA Kester JE Rickard RW Shipp AM 《Environmental science & technology》2005,39(11):3904-3910
An exposure assessment and risk characterization was conducted to better understand the potential human health significance of trace levels of perfluorooctanoate (PFO) detected in certain consumer articles. PFO is the anion of perfluorooctanoic acid (PFOA). Concentrations of PFO in the consumer articles were determined from extraction tests and product formulation information. Potential exposures during consumer use of the articles were quantified based on an assessment of behavior patterns and regulatory guidance. Health benchmarks were developed and then compared to the exposure estimates to yield margins of exposure (MOEs). A simple one-compartment model was also developed to estimate contributions of potential consumer exposures to PFO concentrations in serum. While there are considerable uncertainties in this assessment, it indicates that exposures to PFO during consumer use of the articles evaluated in this study are not expected to cause adverse human health effects in infants, children, adolescents, adult residents, or professionals nor result in quantifiable levels of PFO in human serum. 相似文献