全文获取类型
收费全文 | 252041篇 |
免费 | 3772篇 |
国内免费 | 1045篇 |
专业分类
电工技术 | 4327篇 |
综合类 | 201篇 |
化学工业 | 37110篇 |
金属工艺 | 8221篇 |
机械仪表 | 7265篇 |
建筑科学 | 6785篇 |
矿业工程 | 541篇 |
能源动力 | 7236篇 |
轻工业 | 28637篇 |
水利工程 | 2120篇 |
石油天然气 | 1852篇 |
武器工业 | 5篇 |
无线电 | 33393篇 |
一般工业技术 | 46176篇 |
冶金工业 | 46455篇 |
原子能技术 | 3366篇 |
自动化技术 | 23168篇 |
出版年
2021年 | 1799篇 |
2020年 | 1346篇 |
2019年 | 1666篇 |
2018年 | 2571篇 |
2017年 | 2593篇 |
2016年 | 2875篇 |
2015年 | 2163篇 |
2014年 | 3655篇 |
2013年 | 11954篇 |
2012年 | 6754篇 |
2011年 | 9664篇 |
2010年 | 7445篇 |
2009年 | 8395篇 |
2008年 | 8917篇 |
2007年 | 8931篇 |
2006年 | 8278篇 |
2005年 | 7486篇 |
2004年 | 7208篇 |
2003年 | 7094篇 |
2002年 | 6591篇 |
2001年 | 7021篇 |
2000年 | 6324篇 |
1999年 | 6822篇 |
1998年 | 16377篇 |
1997年 | 11367篇 |
1996年 | 8581篇 |
1995年 | 6543篇 |
1994年 | 5707篇 |
1993年 | 5566篇 |
1992年 | 3996篇 |
1991年 | 3775篇 |
1990年 | 3549篇 |
1989年 | 3369篇 |
1988年 | 3276篇 |
1987年 | 2589篇 |
1986年 | 2487篇 |
1985年 | 3156篇 |
1984年 | 2797篇 |
1983年 | 2559篇 |
1982年 | 2344篇 |
1981年 | 2390篇 |
1980年 | 2201篇 |
1979年 | 2048篇 |
1978年 | 1879篇 |
1977年 | 2176篇 |
1976年 | 2724篇 |
1975年 | 1584篇 |
1974年 | 1489篇 |
1973年 | 1558篇 |
1972年 | 1144篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
981.
Kalichman Seth C.; Russell Robert L.; Hunter Tricia L.; Sarwer David B. 《Canadian Metallurgical Quarterly》1993,61(5):887
The effects of celebrity self-disclosure of HIV seropositivity on perceptions of HIV and AIDS were investigated. AIDS-related interest and knowledge measures were collected from 468 men before and after basketball star Earvin "Magic" Johnson's self-disclosure of HIV seropositivity. Increased interest in AIDS paralleled media coverage of the announcement, with the most substantial effects occurring within 2 wks. Perceived impact of the disclosure was greatest among African-American men and men who had not previously known someone with HIV/AIDS. Celebrity self-disclosure appears to affect perceptions through mechanisms similar to those involved in personally knowing someone infected with HIV. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
982.
The potency of a series of anticholinesterase (anti-ChE) agents and serotonin-related amines as inhibitors of the aryl acylamidase (AAA) activity associated with electric eel acetylcholinesterase (AChE) (EC 3.1.1.7) and horse serum butyrylcholinesterase (BuChE) (EC 3.1.1.8) was examined and compared with the potency of the same compounds as ChE inhibitors. Neostigmine, physostigmine, BW 284C51, (+/-)-huperzine A, E2020, tacrine, edrophonium and heptyl-physostigmine were, in that order, the most potent in inhibiting eel AChE-associated AAA activity, their inhibitor constant (Ki) values being in the range 0.02-0.37 microM. The rank order of the same compounds as AChE inhibitors basically paralleled that of AAA, although they were in general stronger on AChE (Ki = 0.001-0.05). The peripheral anionic site inhibitors propidium and gallamine were inactive on AChE-associated AAA. Serotonin and its derivatives were slightly stronger on AAA (Ki = 7.5-30 microM) than on AChE (Ki = 20-140 microM). Tacrine (IC50 = 0.03 microM), diisopropylfluorophosphate (IC50 = 0.04 microM), heptyl-physostigmine (IC50 = 0.11 microM), physostigmine (IC50 = 0.15 microM) and tetra-iso-propylpyrophosphoramide (iso-OMPA) (IC50 = 0.75 microM) were the most potent in inhibiting horse serum BuChE-associated AAA activity. Serotonin and related amines were very weak on BuChE-associated AAA activity. These results indicate that the inhibitory potencies of the active site anti-ChE agents on the AAA activity associated with eel AChE and horse serum BuChE are closely correlated with their action on the respective ChE. In addition, the efficacy of tacrine, E2020, heptyl-physostigmine and (+/-)-huperzine A in the treatment of Alzheimer's disease is unlikely to be related to the action of these drugs on ChE-associated AAA. 相似文献
983.
984.
P Hourdequin L Bednarczyk R Gabriel G Harika C Quereux P Wahl 《Canadian Metallurgical Quarterly》1996,25(5):528-532
We report three cases of pulmonary edema associated with prolonged intravenous tocolytic therapy with beta 2-adrenergic agonists among patients with multiple pregnancies. Although beta 2-adrenergic agonists may have direct myocardial side-effects, the underlying pathophysiologic mechanisms are mainly noncardiogenic. The most important one appears to be the fluid overload, related to amounts of fluids given intravenously and to direct result of beta-sympathomimetic therapy on renal excretion of sodium and water. Neonatal benefit of prolonged tocolytic therapy remains hypothetical. If this strategy is used, the prevention of cardiovascular adverse effects requires an intensive maternal supervision, especially in case of multiple pregnancy, the use of beta 2-adrenergic agonists in concentrated solution in order to reduce the amounts of fluids given intravenously, and the association with progesterone therapy which can reduce the infusion rate and the duration of tocolytic therapy. 相似文献
985.
AR Hart B Jestico C Antill M Taylor JF Mayberry 《Canadian Metallurgical Quarterly》1996,110(4):247-249
We studied 100 healthy children looking for lactose malabsortion. We performed in all of them the lactose breath test. We found a 10% with lactose malabsortion. There was no correlation between lactose breath test and fecal reducing substances. 相似文献
986.
Eroding poly(DL-lactide-co-glycolide)(PDLLG) washers were observed chronically in vitro and in vivo following loading in a bone chamber tibial implant (BCI). Images were recorded using intravital microscopy of the implanted rabbit and direct pH measurements were obtained of the tissue in the bone chamber using a combination probe-reference microelectrode. While statistically significant pH differences were found between the control (unloaded) and experimental (PDLLG-bearing) BCIs, they were only of the order of 0.2 pH units. This value proved to be physiologically insignificant as no statistically significant difference in bone defect healing, as indicated by angiogenesis, was detected. It was shown that the measured small pH changes during PDLLG washers erosion would result whether the buffer was phosphate-buffered saline replaced weekly or interstitial fluid subject to vascular exchanges. 相似文献
987.
A de Meester C Six P Henin C Scavée R Luwaert JM Chaudron 《Canadian Metallurgical Quarterly》1996,89(12):1673-1676
The authors report the case of a 32 year old woman who was shot with a shotgun. Acute inferior wall infarction was detected fortuitously on electrocardiography and coronary angiography showed occlusion of the right coronary artery with lead shot. The single coronary lesion, absence, of other cardiac complications (haemopericardium, cardiac perforation, ...) and the favourable outcome with conservative medical treatment has not been previously reported to the authors' knowledge. 相似文献
988.
989.
C Bokemeyer O K?hrmann J Tischler L Weissbach U R?th A Haupt P Sch?ffski A Harstrick HJ Schmoll 《Canadian Metallurgical Quarterly》1996,7(10):1015-1021
BACKGROUND: Cisplatin-based combination chemotherapy will cure 70% to 80% of patients with metastatic non-seminomatous germ cell tumors but is associated with the possibility of severe neuro-, oto- and nephro-toxicities. Carboplatin, a cisplatin analogue, is an active drug in testicular cancer with a more favourable spectrum of side effects. In a randomized trial, the German Testicular Cancer Study Group compared a combination regimen of carboplatin, etoposide and bleomycin (CEB) to standard cisplatin, etoposide and bleomycin (PEB) chemotherapy for patients with 'minimal-' and moderate-disease' non-seminomatous germ cell tumors, according to the Indiana University classification. PATIENTS AND METHODS: PEB was given for three cycles at standard doses (given days 1-5), and the CEB regimen consisted of carboplatin (target AUC of 5 mg/ml x min) on day 1, etoposide 120 mg/m2 on days 1 to 3 and bleomycin 30 mg on days 1, 8 and 15. Four cycles of CEB were given, with the omission of bleomycin in the fourth cycle. Thus, the cumulative doses of etoposide and bleomycin applied in the two treatment arms were comparable. Fifty-four patients were entered on the trial, 29 were treated with PEB and 25 with CEB chemotherapy. Patients were stratified according to disease extent (minimal versus moderate) and the degree of tumor marker elevation. Thirty-two patients (59%) belonged to the group with minimal disease and low markers. RESULTS: No significant difference in response to chemotherapy was seen between the two arms, with CR rates of 81% for the PEB arm and 76% for CEB treatment. However, more patients treated with CEB (32% versus 13%) have relapsed after therapy, and 4 patients (16%) have died of disease progression after CEP in contrast to 1 (3%) after PEB therapy. The first interim analysis of negative events (relapse, vital tumor at secondary resection, death from disease and therapy-associated death) showed a significantly higher rate after CEB than after PEB therapy, and the trial was terminated early. After a median follow-up of 33 months for all patients, the calculation of negative events is still significantly in favour of PEB-treated patient, particularly since three late relapses > 2 years have been observed in the CEB arm (P = 0.03). CONCLUSION: This randomized trial demonstrates that even with the use of adequate doses of etoposide and full-dose bleomycin, carboplatin cannot altogether replace cisplatin in patients with testicular cancer. Treatment with the PEB regimen remains the standard approach in patients with 'good-risk' non-seminomatous germ cell tumors. 相似文献
990.
G. Carelli N. Ioli J. C. S. Moraes A. Moretti F. Strumia G. E. Annino A. Bertolini 《Journal of Infrared, Millimeter and Terahertz Waves》1996,17(6):1023-1030
The results described in this work are part of a systematic search for long wavelength laser lines to be used in high magnetic field EPR applications and in plasma diagnostic. Four new far-infrared laser lines of CH2 = CF2 (1,1 difluoroethylene), optically pumped by a waveguide CO2 laser, have been discovered and characterized in wavelength, polarization relative to the pumping radiation and offset relative to the CO2 center frequency. New measurements of polarization and offset of 5 already known laser lines are also reported. A table of all of the known CO2 pumped FIR laser lines from this molecule is given. 相似文献