Relationship between internal calcium and outward current in mammalian ventricular muscle; a mechanism for the control of the action potential duration?

In sheep and calf ventricular bundles, increasing the internal calcium by increasing the frequency of voltage-clamping to plateau range potentials increased the time-independent outward current. This effect was more marked with higher [Ca]o, and was reduced if the Ca current blockers Verapamil or D 600 were used. 2. If the internal Ca was increased by the addition of cyanide and reduction of external sodium the outward current was also increased. The frequency-dependent increase in outward current also occurred in this Na-poor (12 mM) solution. 3. Tension measurement on the ventricular bundles showed that a Na-free solution with cyanide did not cause a contracture. On changing from Tyrode to a Na-free solution containing cyanide, and on changing back to Tyrode there was a potentiation of the twitch. 4. In Na-poor solution with cyanide, although no contracture was found, ECa was less positive, suggesting that under these circumstances Ca accumulates at the inner side of the membrane, but not around the myofibrils. 5. The prolongation of the action potential in Cl-free solution is frequency-dependent. A greater prolongation is seen at lower frequencies suggesting that Cl current is relatively more important for repolarization at lower frequencies of stimulation. 6. It is suggested that calcium at the inner side of the membrane sets the level of the background outward current. A feed-back mechanism on this basis is proposed for the control of the action potential duration. Various factors that could influence this basic mechanism are discussed.     

A case study of defects due to process marginalities in deep sub-micron technology

The difficulties in identifying the precise defect location and real leakage path is increasing as the integrated circuit design and process have become more and more complicated in and below deep sub-micron technology node. Most of the defects causing chip leakage are detectable with only one of the failure analysis (FA) tools such as liquid crystal detection (LCD) or photon emission microscope (PEM). However, due to process marginalities some defects are often not detectable with only one FA tool [Hung-Sung Lin, Wen-Tung Chang, Chun-Lin Chen, Tsui-Hua Huang, Vivian Chiang, Chun-Ming Chen. A study of asymmetrical behaviour in advanced nano SRAM devices. In: 13th IPFA proceedings; July 2006. p. 63–6; Kruseman Bram, Majhi Ananta, Hora Camelia, Eichenberger Stefan, Meirlevede Johan. Systematic defects in deep sub-micron technologies. ITC international test conference, 2004. p. 290–9.]. This paper present an example of an abnormal power consumption process related defect which could only be detected with more advanced FA tools.     

Stability of discrete-time bilinear systems with constant inputs

In this paper discrete-time bilinear systems are considered. Necessary and sufficient conditions are developed which ensure that for any constant input in an unbounded control domain, the trajectories of the system tend to the origin as time increases.     

Development of a multiple linear regression model for predicting the 28-day compressive strength of Portland pozzolan cement

A multiple linear regression model was developed for the prediction of the 28-day compressive strength of Portland Pozzolan Cement (PPC) containing Santorin Earth as an admixture. The independent variables of the model were: (1) the compressive strength at the age of 2 days, (2) the compressive strength after autoclave hydrothermal treatment at 2.07 N/mm² (300 psi) and 214°C for 3 h, (3) the C₃S/C₂S ratio of the clinker, (4) the insoluble residue of the cement, (5) the pozzolanic activity factor and (6) the C₃A content of the clinker. The evaluation of the proposed model was performed by various statistical tests, all of which were successful. These tests included: multiple correlation, test of the significance of coefficients (t-test), estimation of confidence intervals for coefficients, test for outliers and unusual residuals, test for influential points, conditional sums of squares, R-squared and analysis of variance. There was very good agreement between the strength predicted by the multiple regression model and experimental results.

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Résumé Un modèle de régression multiple linéaire a été developpé pour la prédiction de la résistance en compression du ciment pozzolanique Portland, contenant de la Terre de Santorin comme mélange. Les variables indépendantes du modèle étaient: (1) la résistance en compression pour l’age de 2 jours, (2) la résistance en compression après un traitement de 3 heures dans un autoclave à 2,07 N/mm² (300 psi) et 214°C, (3) le rapport C₂S/C₂S du clinker, (4) la quantité d’insolubles du ciment, (5) le facteur d’activité pozzolanique et (6) la quantité de C₃A du clinker. L’évaluation du modèle proposé à été effectuée par une série d’essais statistiques: une corrélation multiple, un essai de signification des coefficients (t-test), estimation des intervalles de confiance pour les coefficients, essai pour les substances étrangères et les résidus inhabituels, essai pour les points d’influence, somme des moindres carrés conditionnels, carré et une analyse de variance. Un très bon accord entre la résistance prévue par le modèle de régression et les résultats expérimentaux, a été constaté.

     

基于最优矢量量化零树编码的多小波图像压缩

提出一种基于多小波变换的矢量量化零树编码方案.利用多小波变换后各个子块之间的相关性,把图像的多小波分解看成是矢量四叉树结构,通过对多小波系数重排来保持小波系数的零树特征.对图像进行压缩仿真试验,结果表明多小波变换的图像压缩结果优于传统的小波变换结果.     

用浮动零点法消除温度对SAW加速度计测量准确度的影响

分析了温度漂移对声表面波谐振器(SAWR)及其声表面波振荡器(SAWO)频率特性、以及对SAW加速度计测量准确性的影响,探讨了提高SAW加速度计测量准确度的方法,提出了一种基于浮动零点原理抑制温度共模干扰的双对SAWR加速度计设计方案.本方案不仅通过设置浮动零点SAWR抑制了SAWO频率-温度漂移对SAW加速度计测量准确度的干扰,还在一定程度上降低了对SAWR表面制造工艺的要求.