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41.
42.
分析了温度漂移对声表面波谐振器(SAWR)及其声表面波振荡器(SAWO)频率特性、以及对SAW加速度计测量准确性的影响,探讨了提高SAW加速度计测量准确度的方法,提出了一种基于浮动零点原理抑制温度共模干扰的双对SAWR加速度计设计方案.本方案不仅通过设置浮动零点SAWR抑制了SAWO频率-温度漂移对SAW加速度计测量准确度的干扰,还在一定程度上降低了对SAWR表面制造工艺的要求. 相似文献
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44.
A multiple linear regression model was developed for the prediction of the 28-day compressive strength of Portland Pozzolan
Cement (PPC) containing Santorin Earth as an admixture. The independent variables of the model were: (1) the compressive strength
at the age of 2 days, (2) the compressive strength after autoclave hydrothermal treatment at 2.07 N/mm2 (300 psi) and 214°C for 3 h, (3) the C3S/C2S ratio of the clinker, (4) the insoluble residue of the cement, (5) the pozzolanic activity factor and (6) the C3A content of the clinker. The evaluation of the proposed model was performed by various statistical tests, all of which were
successful. These tests included: multiple correlation, test of the significance of coefficients (t-test), estimation of confidence
intervals for coefficients, test for outliers and unusual residuals, test for influential points, conditional sums of squares,
R-squared and analysis of variance. There was very good agreement between the strength predicted by the multiple regression
model and experimental results.
Résumé Un modèle de régression multiple linéaire a été developpé pour la prédiction de la résistance en compression du ciment pozzolanique Portland, contenant de la Terre de Santorin comme mélange. Les variables indépendantes du modèle étaient: (1) la résistance en compression pour l’age de 2 jours, (2) la résistance en compression après un traitement de 3 heures dans un autoclave à 2,07 N/mm2 (300 psi) et 214°C, (3) le rapport C2S/C2S du clinker, (4) la quantité d’insolubles du ciment, (5) le facteur d’activité pozzolanique et (6) la quantité de C3A du clinker. L’évaluation du modèle proposé à été effectuée par une série d’essais statistiques: une corrélation multiple, un essai de signification des coefficients (t-test), estimation des intervalles de confiance pour les coefficients, essai pour les substances étrangères et les résidus inhabituels, essai pour les points d’influence, somme des moindres carrés conditionnels, carré et une analyse de variance. Un très bon accord entre la résistance prévue par le modèle de régression et les résultats expérimentaux, a été constaté.相似文献
45.
In this paper discrete-time bilinear systems are considered. Necessary and sufficient conditions are developed which ensure that for any constant input in an unbounded control domain, the trajectories of the system tend to the origin as time increases. 相似文献
46.
KA Birkness M Deslauriers JH Bartlett EH White CH King FD Quinn 《Canadian Metallurgical Quarterly》1999,67(2):653-658
A tissue culture bilayer system that mimics some aspects of early alveolar infection by Mycobacterium tuberculosis was developed. This model incorporates human lung epithelial type II pneumocyte (A549) (upper chamber) and endothelial cell (lower chamber) layers separated by a microporous membrane. This construction makes it possible to observe and quantify the passage of bacteria through the two layers, to observe the interaction of the bacteria with the various cell types, and to examine the basic mechanisms of immune cell recruitment to the site of infection. After 10(7) organisms were added to the upper chamber we microscopically observed large numbers of bacteria attached to and within the pneumocytes and we determined by viable-cell counting that a small percentage of the inoculum (0.02 to 0.43%) passed through the bilayer into the lower chamber. When peripheral blood mononuclear cells were added to the lower chamber, microscopic examination indicated a migration of the mononuclear cells through the bilayer to the apical surface, where they were seen associated with the mycobacteria on the pneumocytes. The added complexity of the bilayer system offers an opportunity to define more precisely the roles of the various lung cell types in the pathogenesis of early tuberculosis. 相似文献
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48.
CH Bird VR Sutton J Sun CE Hirst A Novak S Kumar JA Trapani PI Bird 《Canadian Metallurgical Quarterly》1998,18(11):6387-6398
Cytotoxic lymphocytes (CLs) induce caspase activation and apoptosis of target cells either through Fas activation or through release of granule cytotoxins, particularly granzyme B. CLs themselves resist granule-mediated apoptosis but are eventually cleared via Fas-mediated apoptosis. Here we show that the CL cytoplasmic serpin proteinase inhibitor 9 (PI-9) can protect transfected cells against apoptosis induced by either purified granzyme B and perforin or intact CLs. A PI-9 P1 mutant (Glu to Asp) is a 100-fold-less-efficient granzyme B inhibitor that no longer protects against granzyme B-mediated apoptosis. PI-9 is highly specific for granzyme B because it does not inhibit eight of the nine caspases tested or protect transfected cells against Fas-mediated apoptosis. In contrast, the P1(Asp) mutant is an effective caspase inhibitor that protects against Fas-mediated apoptosis. We propose that PI-9 shields CLs specifically against misdirected granzyme B to prevent autolysis or fratricide, but it does not interfere with homeostatic deletion via Fas-mediated apoptosis. 相似文献
49.
G. Von Freymann CH. Adelmann G. Scheiber TH. Schimmel & M. Wegener 《Journal of microscopy》1999,194(2-3):491-494
The depolarization near-field scanning optical microscope allows for sub-wavelength optical resolution with uncoated optical fibre tips. We show by a simple thought experiment, by numerical solution of the Maxwell equations for a realistic geometry, and by direct experiments, that this novel apparatus images gradients of the dielectric function of a sample in the direction of the incident electric field vector. The near-field images obtained from experiment and theory agree well. 相似文献
50.
Type-specific serologic assays for herpes simplex virus (HSV) types 1 and 2 based on glycoprotein G-1 (gG-1) (HSV-1) and gG-2 (HSV-2) discriminate between antibodies against HSV-1 and HSV-2. We previously developed a Western blot assay using gG-1 and gG-2 expressed in baculovirus, performed extensive validation studies, and determined that it was both sensitive and specific for type-specific detection of HSV antibody. Here we report that, among a cohort of Thai military recruits, the serostatus of some individuals changed from positive to negative over time (6.6% among those ever positive for HSV-1, and 14.9% among those ever positive for HSV-2). We tested a subset of these specimens in three other gG-based assays: an enzyme-linked immunosorbent assay, an immunoblot strip assay, and a Western blot assay. Positive-to-negative shifts occurred in every assay; the frequency of the shifts ranged from 6. 1% to 21.2% of the specimen sets tested. There was only limited agreement among the assays concerning which individuals lost reactivity. This inaccuracy, exhibited by all of the assay protocols, was not predicted by validation studies employing specimens from cross-sectional studies and was most pronounced in HSV-2 testing. This argues for the inclusion of serial blood specimens in serologic assay validation procedures. 相似文献